Reviewed, UniProtKB/Swiss-Prot Q42896 (SCRK2_SOLLC)

Names and origin

Protein names

Recommended name:
    Fructokinase-2
    EC=2.7.1.4

Gene names

Name:

FRK2

Organism

Solanum lycopersicum (Tomato) (Lycopersicon esculentum)

Taxonomic identifier

4081 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon

Protein attributes

Sequence length	328 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	May play an important role in maintaining the flux of carbon towards starch formation By similarity.
Catalytic activity	ATP + D-fructose = ADP + D-fructose 6-phosphate.
Pathway	Glycan biosynthesis; starch biosynthesis.
Sequence similarities	Belongs to the carbohydrate kinase pfkB family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Gene Ontology (GO)
Biological process	D-ribose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW fructokinase activity Inferred from electronic annotation. Source: EC ribokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 328	328	Fructokinase-2		PRO_0000252670

Sequences

	Sequence		Length	Mass (Da)
	Q42896-1 [UniParc]. Last modified July 1, 1997. Version 2. Checksum: B4EA6456D439B4F4	FASTA	328	34,763
	10 20 30 40 50 60 MAVNGASSSG LIVSFGEMLI DFVPTVSGVS LAEAPGFLKA PGGAPANVAI AVTRLGGKSA 70 80 90 100 110 120 FVGKLGDDEF GHMLAGILKT NGVQAEGINF DKGARTALAF VTLRADGERE FMFYRNPSAD 130 140 150 160 170 180 MLLTPAELNL DLIRSAKVFH YGSISLIVEP CRAAHMKAME VAKEAGALLS YDPNLRLPLW 190 200 210 220 230 240 PSAEEAKKQI KSIWDSADVI KVSDVELEFL TGSNKIDDES AMSLWHPNLK LLLVTLGEKG 250 260 270 280 290 300 CNYYTKKFHG TVGGFHVKTV DTTGAGDSFV GALLTKIVDD QTILEDEARL KEVLRFSCAC 310 320 GAITTTKKGA IPALPTASEA LTLLKGGA

References

[1]	"Molecular cloning and analysis of fructokinase expression in tomato (Lycopersicon esculentum Mill.)." Martinez-Barajas E., Luethy M.H., Randall D.D. Plant Sci. 125:13-20(1997) Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Divergent fructokinase genes are differentially expressed in tomato." Kanayama Y., Dai N., Granot D., Petreikov M., Schaffer A., Bennett A.B. Plant Physiol. 113:1379-1384(1997) [PubMed: 9112782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U62329 mRNA. Translation: AAB51108.1. U64818 mRNA. Translation: AAB57734.1.
UniGene	Les.135
3D structure databases
HSSP	HSSP built from PDB template 1LII based on UniProtKB Q9TVW2.
ModBase	Search...
2-D gel databases
ANU-2DPAGE	Q42896.
Family and domain databases
InterPro	IPR011611. Carb/pur_kinase. IPR002173. Carboh/pur_kinase_PfkB_CS. IPR002139. Ribokinase. [Graphical view]
Pfam	PF00294. PfkB. 1 hit. [Graphical view]
PRINTS	PR00990. RIBOKINASE.
PROSITE	PS00583. PFKB_KINASES_1. 1 hit. PS00584. PFKB_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCRK2_SOLLC

Accession

Primary (citable) accession number: Q42896
Secondary accession number(s): O04994

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	July 1, 1997
Last modified:	June 16, 2009
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)