Q42881 (1A13_SOLLC) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 73.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 1-aminocyclopropane-1-carboxylate synthase 3 Short name=ACC synthase 3 EC=4.4.1.14 Alternative name(s): Le-ACS3 Short name=ACS-3 S-adenosyl-L-methionine methylthioadenosine-lyase 3 | ||
| Gene names |
| ||
| Organism | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [Reference proteome] | ||
| Taxonomic identifier | 4081 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Lycopersicon![]() |
Protein attributes
| Sequence length | 469 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants. |
| Catalytic activity | S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine. |
| Cofactor | Pyridoxal phosphate. |
| Pathway | |
| Subunit structure | Homodimer By similarity. |
| Induction | By flooding. |
| Sequence similarities | Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Ethylene biosynthesis Fruit ripening |
| Ligand | Pyridoxal phosphate S-adenosyl-L-methionine |
| Molecular function | Lyase |
| Technical term | Complete proteome Direct protein sequencing Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | 1-aminocyclopropane-1-carboxylate biosynthetic process Inferred from electronic annotation. Source: GOC ethylene biosynthetic processInferred from electronic annotation. Source: UniProtKB-UniPathway fruit ripeningInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular_function | 1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 469 | 469 | 1-aminocyclopropane-1-carboxylate synthase 3 | PRO_0000123913 | |||||
Amino acid modifications | |||||||||
| Modified residue | 272 | 1 | N6-(pyridoxal phosphate)lysine | ||||||
Experimental info | |||||||||
| Sequence conflict | 243 | 1 | F → L in AAB48945. Ref.2 | ||||||
| Sequence conflict | 335 | 1 | K → R in AAB48945. Ref.2 | ||||||
Sequences
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References
| [1] | "Analysis of LE-ACS3, a 1-aminocyclopropane-1-carboxylic acid synthase gene expressed during flooding in the roots of tomato plants." Olson D.C., Oetiker J.H., Yang S.F. J. Biol. Chem. 270:14056-14061(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. VFN8. Tissue: Leaf and Root. |
| [2] | "The tomato 1-aminocyclopropane-1-carboxylate (ACC) synthase multigene family is encoded by at least eight members." Kawakita K., Hennig L., Rottmann W.R., Yu G.X., Zarembinski T.I., Taylor L.D., Theologis A. Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Rutgers. |
| [3] | "Characterization and sequencing of the active site of 1-aminocyclopropane-1-carboxylate synthase." Yip W.K., Dong J.G., Kenny J.W., Thompson G.A., Yang S.F. Proc. Natl. Acad. Sci. U.S.A. 87:7930-7934(1990) [PubMed] [Europe PMC] [Abstract] Cited for: PARTIAL PROTEIN SEQUENCE. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L34171 Genomic DNA. Translation: AAA78789.1. U18055 Genomic DNA. Translation: AAB48946.1. U17972 mRNA. Translation: AAB48945.1. |
| PIR | A57540. |
| RefSeq | NP_001234026.1. NM_001247097.1. |
| UniGene | Les.3642. |
3D structure databases | |
| ProteinModelPortal | Q42881. |
| SMR | Q42881. Positions 12-428. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblPlants | Solyc02g091990.2.1; Solyc02g091990.2.1; Solyc02g091990.2. |
| GeneID | 778292. |
Enzyme and pathway databases | |
| BRENDA | 4.4.1.14. 3101. |
| UniPathway | UPA00384; UER00562. |
Family and domain databases | |
| Gene3D | 3.40.640.10. 1 hit. 3.90.1150.10. 1 hit. |
| InterPro | IPR004839. Aminotransferase_I/II. IPR004838. NHTrfase_class1_PyrdxlP-BS. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view] |
| Pfam | PF00155. Aminotran_1_2. 1 hit. [Graphical view] |
| SUPFAM | SSF53383. PyrdxlP-dep_Trfase_major. 1 hit. |
| PROSITE | PS00105. AA_TRANSFER_CLASS_1. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | 1A13_SOLLC | ||||||||
| Accession | Primary (citable) accession number: Q42881 Secondary accession number(s): Q96571 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Plant Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
