ID   PLSC_LIMAL              Reviewed;         281 AA.
AC   Q42868;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 39.
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase;
DE            Short=1-AGP acyltransferase;
DE            Short=1-AGPAT;
DE            EC=2.3.1.51;
DE   AltName: Full=Lysophosphatidic acid acyltransferase;
DE            Short=LPAAT;
OS   Limnanthes alba (White meadowfoam).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids II; Brassicales; Limnanthaceae; Limnanthes.
OX   NCBI_TaxID=42439;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Alba;
RX   MEDLINE=96106201; PubMed=8539298; DOI=10.1104/pp.109.4.1389;
RA   Lassner M.W., Levering C.K., Davies H.M.D., Knutzon D.S.;
RT   "Lysophosphatidic acid acyltransferase from meadowfoam mediates
RT   insertion of erucic acid at the sn-2 position of triacylglycerol in
RT   transgenic rapeseed oil.";
RL   Plant Physiol. 109:1389-1394(1995).
CC   -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic
CC       acid by incorporating acyl moiety at the 2 position. This enzyme
CC       uses erucoyl-CoA as an acyl donor.
CC   -!- CATALYTIC ACTIVITY: Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate =
CC       CoA + 1,2-diacyl-sn-glycerol 3-phosphate.
CC   -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis;
CC       CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
CC       (Potential).
CC   -!- DOMAIN: The HXXXXD motif is essential for acyltransferase activity
CC       and may constitute the binding site for the phosphate moiety of
CC       the glycerol-3-phosphate (By similarity).
CC   -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC       acyltransferase family.
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DR   EMBL; U32988; AAC49185.1; -; mRNA.
DR   BRENDA; 2.3.1.51; 295322.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferas...; IEA:EC.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR002123; Acyltransferase.
DR   InterPro; IPR004552; AGP_acyltrans.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   SMART; SM00563; PlsC; 1.
DR   TIGRFAMs; TIGR00530; AGP_acyltrn; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Membrane; Phospholipid biosynthesis; Transferase;
KW   Transmembrane.
FT   CHAIN         1    281       1-acyl-sn-glycerol-3-phosphate
FT                                acyltransferase.
FT                                /FTId=PRO_0000208186.
FT   TRANSMEM     40     60       Potential.
FT   TRANSMEM     71     91       Potential.
FT   TRANSMEM    110    130       Potential.
FT   MOTIF       109    114       HXXXXD motif.
SQ   SEQUENCE   281 AA;  31665 MW;  2725B811777A6067 CRC64;
     MAKTRTSSLR NRRQLKTAVA ATADDDKDGI FMVLLSCFKI FVCFAIVLIT AVAWGLIMVL
     LLPWPYMRIR LGNLYGHIIG GLVIWLYGIP IEIQGSEHTK KRAIYISNHA SPIDAFFVMW
     LAPIGTVGVA KKEVIWYPLL GQLYTLAHHI RIDRSNPAAA IQSMKEAVRV ITEKNLSLIM
     FPEGTRSGDG RLLPFKKGFV HLALQSHLPI VPMILTGTHL AWRKGTFRVR PVPITVKYLP
     PINTDDWTVD KIDDYVKMIH DIYVRNLPAS QKPLGSTNRS K
//