ID   HEM6_HORVU              Reviewed;         391 AA.
AC   Q42840;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 54.
DE   RecName: Full=Coproporphyrinogen-III oxidase, chloroplastic;
DE            Short=Coproporphyrinogenase;
DE            Short=Coprogen oxidase;
DE            EC=1.3.3.3;
DE   Flags: Precursor;
GN   Name=CPX;
OS   Hordeum vulgare (Barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Pooideae; Triticeae; Hordeum.
OX   NCBI_TaxID=4513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Svalofs Bonus; TISSUE=Leaf;
RX   MEDLINE=96073433; PubMed=7580857; DOI=10.1007/BF00197347;
RA   Kruse E., Mock H.-P., Grimm B.;
RT   "Coproporphyrinogen III oxidase from barley and tobacco -- sequence
RT   analysis and initial expression studies.";
RL   Planta 196:796-803(1995).
CC   -!- CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) =
CC       protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
CC   -!- PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis;
CC       protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step
CC       1/1.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast (Probable).
CC   -!- SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase
CC       family.
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DR   EMBL; X82830; CAA58037.1; -; mRNA.
DR   PIR; T04486; T04486.
DR   Gramene; Q42840; -.
DR   BRENDA; 1.3.3.3; 283.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:EC.
DR   GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR001260; Coprogen_oxidas.
DR   InterPro; IPR018375; Coproporphyrinogen-3_ox_CS.
DR   Gene3D; G3DSA:3.40.1500.10; Coprogen_oxidas; 1.
DR   PANTHER; PTHR10755; Coprogen_oxidas; 1.
DR   Pfam; PF01218; Coprogen_oxidas; 1.
DR   PIRSF; PIRSF000166; Coproporphyri_ox; 1.
DR   PRINTS; PR00073; COPRGNOXDASE.
DR   PROSITE; PS01021; COPROGEN_OXIDASE; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Heme biosynthesis; Oxidoreductase; Plastid;
KW   Porphyrin biosynthesis; Transit peptide.
FT   TRANSIT       1      ?       Chloroplast (Potential).
FT   CHAIN         ?    391       Coproporphyrinogen-III oxidase,
FT                                chloroplastic.
FT                                /FTId=PRO_0000006032.
SQ   SEQUENCE   391 AA;  43556 MW;  BD3549559F2EB2CB CRC64;
     MASSLLTTPS QTLAPNPAAA RARRSSPAAA QVSFSSPLLP GRRALRCARP VAIEKEVPEK
     EAPTTFLRED GSGAGSGSVR ERFEGMIRRV QGEICAALEE ADGSGKRFVE DVWSRPGGVC
     VHSRVLQDGN VFEKAGVNVS AVIGVCPRSA YRAAKGAAKN GAADGHKAGP VPFFSAGISS
     VLHPKNPFAP TLHFNYRYFE TDAPKDVPGA PRSWWFGGGT DLTPSYLIEE DVKHFHSVQK
     QTCDKFDPSF YPRFKKWCDD YFYIKHRNER RGLGGIFFDD LNDYDQDMLL NFATECAGSV
     IPAYIPIIER RKDTPFNEEQ KAWQQVRRGR YVEFNLVYDR GTTFGLKTGG RIESILVSLP
     LTARWEYDHK PEEGSEEWKL LDACINPKEW L
//