Reviewed, UniProtKB/Swiss-Prot Q42840 (HEM6_HORVU)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen III oxidase, chloroplastic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:

CPX

Organism

Hordeum vulgare (Barley)

Taxonomic identifier

4513 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Hordeum

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	Plastid › chloroplastProbable.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Heme biosynthesis Porphyrin biosynthesis
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	heme biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Chloroplast Potential
	Chain	? – 391		Coproporphyrinogen III oxidase, chloroplastic		PRO_0000006032

Sequences

	Sequence		Length	Mass (Da)
	Q42840-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: BD3549559F2EB2CB	FASTA	391	43,556
	10 20 30 40 50 60 MASSLLTTPS QTLAPNPAAA RARRSSPAAA QVSFSSPLLP GRRALRCARP VAIEKEVPEK 70 80 90 100 110 120 EAPTTFLRED GSGAGSGSVR ERFEGMIRRV QGEICAALEE ADGSGKRFVE DVWSRPGGVC 130 140 150 160 170 180 VHSRVLQDGN VFEKAGVNVS AVIGVCPRSA YRAAKGAAKN GAADGHKAGP VPFFSAGISS 190 200 210 220 230 240 VLHPKNPFAP TLHFNYRYFE TDAPKDVPGA PRSWWFGGGT DLTPSYLIEE DVKHFHSVQK 250 260 270 280 290 300 QTCDKFDPSF YPRFKKWCDD YFYIKHRNER RGLGGIFFDD LNDYDQDMLL NFATECAGSV 310 320 330 340 350 360 IPAYIPIIER RKDTPFNEEQ KAWQQVRRGR YVEFNLVYDR GTTFGLKTGG RIESILVSLP 370 380 390 LTARWEYDHK PEEGSEEWKL LDACINPKEW L

References

[1]	"Coproporphyrinogen III oxidase from barley and tobacco -- sequence analysis and initial expression studies." Kruse E., Mock H.-P., Grimm B. Planta 196:796-803(1995) [PubMed: 7580857] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Svalofs Bonus. Tissue: Leaf.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X82830 mRNA. Translation: CAA58037.1.
PIR	T04486.
3D structure databases
ModBase	Search...
Organism-specific databases
Gramene	Q42840.
Family and domain databases
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_HORVU

Accession

Primary (citable) accession number: Q42840

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	November 25, 2008
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)