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Protein

Thionin BTH7

Gene
N/A
Organism
Hordeum vulgare (Barley)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Toxin

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Thionin BTH7
Cleaved into the following 2 chains:
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeHordeinaeHordeum

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 7446Thionin BTH7PRO_0000034122Add
BLAST
Chaini75 – 13763Acidic proteinPRO_0000034123Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi31 ↔ 68By similarity
Disulfide bondi32 ↔ 60By similarity
Disulfide bondi40 ↔ 58By similarity
Disulfide bondi44 ↔ 54By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ42838.
SMRiQ42838. Positions 29-74.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.30.1350.10. 1 hit.
InterProiIPR001010. Thionin.
[Graphical view]
PfamiPF00321. Thionin. 1 hit.
[Graphical view]
PRINTSiPR00287. THIONIN.
SUPFAMiSSF57429. SSF57429. 1 hit.
PROSITEiPS00271. THIONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q42838-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATNKSIKSV VICVLILGLV LEQVQVEGKS CCKNTTGRNC YNACRFAGGS
60 70 80 90 100
RPVCATACGC KIISGPTCPR DYPKLNLLPE SGEPNVTEYC TIGCRTSVCD
110 120 130
NMDNVSRGQE MKFDMGLCSN ACARFCNDGE VIQSVEA
Length:137
Mass (Da):14,676
Last modified:November 1, 1996 - v1
Checksum:i7BDBAF7082F205BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L36883 Genomic DNA. Translation: AAA91048.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L36883 Genomic DNA. Translation: AAA91048.1.

3D structure databases

ProteinModelPortaliQ42838.
SMRiQ42838. Positions 29-74.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.1350.10. 1 hit.
InterProiIPR001010. Thionin.
[Graphical view]
PfamiPF00321. Thionin. 1 hit.
[Graphical view]
PRINTSiPR00287. THIONIN.
SUPFAMiSSF57429. SSF57429. 1 hit.
PROSITEiPS00271. THIONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Specific and distinct expression patterns of two members of the thionin multigene family of barley in transgenic tobacco."
    Holtorf S., Schuetz C., Apel K., Bohlmann H.
    Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiTHN7_HORVU
AccessioniPrimary (citable) accession number: Q42838
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: November 1, 1996
Last modified: February 17, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.