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Q42806

- KPYC_SOYBN

UniProt

Q42806 - KPYC_SOYBN

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Protein
Pyruvate kinase, cytosolic isozyme
Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactori

Magnesium By similarity.
Potassium By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei51 – 511Substrate By similarity
Metal bindingi53 – 531Potassium By similarity
Metal bindingi55 – 551Potassium By similarity
Metal bindingi85 – 851Potassium By similarity
Metal bindingi86 – 861Potassium; via carbonyl oxygen By similarity
Sitei241 – 2411Transition state stabilizer By similarity
Metal bindingi243 – 2431Magnesium Reviewed prediction
Binding sitei266 – 2661Substrate; via amide nitrogen By similarity
Metal bindingi267 – 2671Magnesium By similarity
Binding sitei267 – 2671Substrate; via amide nitrogen By similarity
Binding sitei299 – 2991Substrate By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. magnesium ion binding Source: InterPro
  3. potassium ion binding Source: InterPro
  4. pyruvate kinase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
  2. response to cadmium ion Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium, Pyruvate

Enzyme and pathway databases

UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinase, cytosolic isozyme (EC:2.7.1.40)
Short name:
PK
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Chromosome 5

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: EnsemblPlants/Gramene
  2. plasma membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511Pyruvate kinase, cytosolic isozyme
PRO_0000112125Add
BLAST

Proteomic databases

PRIDEiQ42806.
ProMEXiQ42806.

Expressioni

Gene expression databases

GenevestigatoriQ42806.

Interactioni

Subunit structurei

Homotetramer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ42806.

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate kinase family.

Phylogenomic databases

KOiK00873.
OMAiVESDPTY.

Family and domain databases

Gene3Di2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.
PROSITEiPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q42806-1 [UniParc]FASTAAdd to Basket

« Hide

MANIDIEGIL KQQQPYDGRV PKTKIVCTLG PASRSVEMTE KLLRAGMNVA    50
RFNFSHGTHD YHQETLNNLK TAMHNTGILC AVMLDTKGPE IRTGFLKDGK 100
PIQLKEGQEV TITTDYDIKG DPEMISMSYK KLPVHLKPGN TILCSDGTIT 150
LTVLSCDPDA GTVRCRCENT ATLGERKNVN LPGVVVDLPT LTEKDKEDIL 200
GWGVPNKIDM IALSFVRKGS DLVNVRKVLG PHAKNIQLMS KVENQEGVLN 250
FDEILRETDA FMVARGDLGM EIPVEKIFLA QKMMIYKCNL VGKPVVTATQ 300
MLESMIKSPR PTRAEATDVA NAVLDGTDCV MLSGESAAGA YPELAVKIMA 350
RICIEAESSL DYGAIFKEMI RSTPLPMSPL ESLASSAVRT ANKAKAKLIV 400
VLTRGGSTAK LVAKYRPAVP ILSVVVPVLS TDSFDWTCSD ETPARHSLIY 450
RGLIPILGEG SAKATDAEST EVILEAALKS ATERALCKPG DAVVALHRIG 500
AASVIKICIV K 511
Length:511
Mass (Da):55,302
Last modified:November 1, 1996 - v1
Checksum:iBF0C06DAC6FD95F1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L08632 mRNA. Translation: AAA17000.1.
PIRiT07787.
RefSeqiNP_001237968.1. NM_001251039.1.
UniGeneiGma.4073.

Genome annotation databases

EnsemblPlantsiGLYMA05G09310.1; GLYMA05G09310.1; GLYMA05G09310.
GLYMA05G09310.2; GLYMA05G09310.2; GLYMA05G09310.
GeneIDi547791.
KEGGigmx:547791.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L08632 mRNA. Translation: AAA17000.1 .
PIRi T07787.
RefSeqi NP_001237968.1. NM_001251039.1.
UniGenei Gma.4073.

3D structure databases

ProteinModelPortali Q42806.
ModBasei Search...

Proteomic databases

PRIDEi Q42806.
ProMEXi Q42806.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi GLYMA05G09310.1 ; GLYMA05G09310.1 ; GLYMA05G09310 .
GLYMA05G09310.2 ; GLYMA05G09310.2 ; GLYMA05G09310 .
GeneIDi 547791.
KEGGi gmx:547791.

Phylogenomic databases

KOi K00873.
OMAi VESDPTY.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00188 .

Gene expression databases

Genevestigatori Q42806.

Family and domain databases

Gene3Di 2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProi IPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view ]
PANTHERi PTHR11817. PTHR11817. 1 hit.
Pfami PF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view ]
PRINTSi PR01050. PYRUVTKNASE.
SUPFAMi SSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsi TIGR01064. pyruv_kin. 1 hit.
PROSITEi PS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A pyruvate kinase cDNA from soybean somatic embryos."
    Ma H., McMullen M.D., Finer J.J.
    Plant Physiol. 102:1345-1345(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiKPYC_SOYBN
AccessioniPrimary (citable) accession number: Q42806
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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