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Q42806

- KPYC_SOYBN

UniProt

Q42806 - KPYC_SOYBN

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Protein

Pyruvate kinase, cytosolic isozyme

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactori

Magnesium.By similarity
Potassium.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei51 – 511SubstrateBy similarity
Metal bindingi53 – 531PotassiumBy similarity
Metal bindingi55 – 551PotassiumBy similarity
Metal bindingi85 – 851PotassiumBy similarity
Metal bindingi86 – 861Potassium; via carbonyl oxygenBy similarity
Sitei241 – 2411Transition state stabilizerBy similarity
Metal bindingi243 – 2431MagnesiumSequence Analysis
Binding sitei266 – 2661Substrate; via amide nitrogenBy similarity
Metal bindingi267 – 2671MagnesiumBy similarity
Binding sitei267 – 2671Substrate; via amide nitrogenBy similarity
Binding sitei299 – 2991SubstrateBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. magnesium ion binding Source: InterPro
  3. potassium ion binding Source: InterPro
  4. pyruvate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium, Pyruvate

Enzyme and pathway databases

UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinase, cytosolic isozyme (EC:2.7.1.40)
Short name:
PK
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Chromosome 5

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511Pyruvate kinase, cytosolic isozymePRO_0000112125Add
BLAST

Proteomic databases

PRIDEiQ42806.
ProMEXiQ42806.

Expressioni

Gene expression databases

GenevestigatoriQ42806.

Interactioni

Subunit structurei

Homotetramer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ42806.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyruvate kinase family.Curated

Phylogenomic databases

InParanoidiQ42806.
KOiK00873.
OMAiVESDPTY.

Family and domain databases

Gene3Di2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProiIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view]
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.
PROSITEiPS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q42806-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MANIDIEGIL KQQQPYDGRV PKTKIVCTLG PASRSVEMTE KLLRAGMNVA
60 70 80 90 100
RFNFSHGTHD YHQETLNNLK TAMHNTGILC AVMLDTKGPE IRTGFLKDGK
110 120 130 140 150
PIQLKEGQEV TITTDYDIKG DPEMISMSYK KLPVHLKPGN TILCSDGTIT
160 170 180 190 200
LTVLSCDPDA GTVRCRCENT ATLGERKNVN LPGVVVDLPT LTEKDKEDIL
210 220 230 240 250
GWGVPNKIDM IALSFVRKGS DLVNVRKVLG PHAKNIQLMS KVENQEGVLN
260 270 280 290 300
FDEILRETDA FMVARGDLGM EIPVEKIFLA QKMMIYKCNL VGKPVVTATQ
310 320 330 340 350
MLESMIKSPR PTRAEATDVA NAVLDGTDCV MLSGESAAGA YPELAVKIMA
360 370 380 390 400
RICIEAESSL DYGAIFKEMI RSTPLPMSPL ESLASSAVRT ANKAKAKLIV
410 420 430 440 450
VLTRGGSTAK LVAKYRPAVP ILSVVVPVLS TDSFDWTCSD ETPARHSLIY
460 470 480 490 500
RGLIPILGEG SAKATDAEST EVILEAALKS ATERALCKPG DAVVALHRIG
510
AASVIKICIV K
Length:511
Mass (Da):55,302
Last modified:November 1, 1996 - v1
Checksum:iBF0C06DAC6FD95F1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L08632 mRNA. Translation: AAA17000.1.
PIRiT07787.
RefSeqiNP_001237968.1. NM_001251039.1.
UniGeneiGma.4073.

Genome annotation databases

EnsemblPlantsiGLYMA05G09310.1; GLYMA05G09310.1; GLYMA05G09310.
GLYMA05G09310.2; GLYMA05G09310.2; GLYMA05G09310.
GeneIDi547791.
KEGGigmx:547791.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L08632 mRNA. Translation: AAA17000.1 .
PIRi T07787.
RefSeqi NP_001237968.1. NM_001251039.1.
UniGenei Gma.4073.

3D structure databases

ProteinModelPortali Q42806.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q42806.
ProMEXi Q42806.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi GLYMA05G09310.1 ; GLYMA05G09310.1 ; GLYMA05G09310 .
GLYMA05G09310.2 ; GLYMA05G09310.2 ; GLYMA05G09310 .
GeneIDi 547791.
KEGGi gmx:547791.

Phylogenomic databases

InParanoidi Q42806.
KOi K00873.
OMAi VESDPTY.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00188 .

Gene expression databases

Genevestigatori Q42806.

Family and domain databases

Gene3Di 2.40.33.10. 1 hit.
3.20.20.60. 2 hits.
3.40.1380.20. 1 hit.
InterProi IPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR015806. Pyrv_Knase_insert_dom.
[Graphical view ]
PANTHERi PTHR11817. PTHR11817. 1 hit.
Pfami PF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view ]
PRINTSi PR01050. PYRUVTKNASE.
SUPFAMi SSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsi TIGR01064. pyruv_kin. 1 hit.
PROSITEi PS00110. PYRUVATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A pyruvate kinase cDNA from soybean somatic embryos."
    Ma H., McMullen M.D., Finer J.J.
    Plant Physiol. 102:1345-1345(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiKPYC_SOYBN
AccessioniPrimary (citable) accession number: Q42806
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3