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Reviewed, UniProtKB/Swiss-Prot Q42649 (F16P2_BETVU)

Last modified June 16, 2009. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase, cytosolic
      Short name=FBPase
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase
OrganismBeta vulgaris (Sugar beet)
Taxonomic identifier161934 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › Caryophyllales › Amaranthaceae › Beta

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Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.

Cofactor

Binds 3 magnesium ions per subunit By similarity.

Subcellular location

Cytoplasm.

Miscellaneous

In plants there are two FBPase isozymes: one in the cytosol and the other in the chloroplast.

Sequence similarities

Belongs to the FBPase class 1 family.

Sequence caution

The sequence AAA32915.1 differs from that shown. Reason: Frameshift at position 8.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341Fructose-1,6-bisphosphatase, cytosolic
PRO_0000200513

Regions

Region124 – 1274Substrate binding By similarity

Sites

Metal binding711Magnesium 1 By similarity
Metal binding1001Magnesium 1 By similarity
Metal binding1001Magnesium 2 By similarity
Metal binding1211Magnesium 2 By similarity
Metal binding1211Magnesium 3 By similarity
Metal binding1231Magnesium 2; via carbonyl oxygen By similarity
Metal binding1241Magnesium 3 By similarity
Metal binding2831Magnesium 3 By similarity
Binding site2151Substrate By similarity
Binding site2471Substrate By similarity
Binding site2671Substrate By similarity
Binding site2771Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q42649-1 [UniParc].

Last modified September 27, 2005. Version 2.
Checksum: 7DCC6D68B7D3FC87

FASTA34137,247
        10         20         30         40         50         60 
MDHAADATRT DLMTITRFVL NEQSKRPESR GDFTILMSHI VLGCKFVCSA VNKAGLAKLI 

        70         80         90        100        110        120 
GLAGETNIQG EEQKKLDVLS NEVFIKALIS SGRTCILVSE EDEEATFVEP SLRGKYCVVF 

       130        140        150        160        170        180 
DPLDGCSNID CGVSIGTIFG IYMVKDLNNA TLDDVLQPGK NMVAAGYCMY GSSCTLVMST 

       190        200        210        220        230        240 
GSGVNGFTHD PSLGEFILTH PDIKIPKKGK IYSVNEGNAK NWDGPTTKYV EKCKFPKDGS 

       250        260        270        280        290        300 
SPKSLRYIGS MVADVHRTLL YGGIFMYPGD KKSPNGKLRV LYEVFPMSFL MEQAGGQAFT 

       310        320        330        340 
GEQRALDLVP KNIHDRSPVF LGSYDDVEDI KALYAAEQKN A

« Hide

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References

[1]"Cloning and nucleotide sequence of a cDNA encoding the cytosolic fructose-1,6-bisphosphatases of sugarbeet (Beta Vulgaris L.)."
Harn C.H., Daie J.
Submitted (MAR-1992) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Leaf.
[2]"Cloning and nucleotide sequence of a complementary DNA encoding the cytosolic fructose-1,6-bisphosphatase of sugar beet (Beta vulgaris L.)."
Harn C.H., Daie J.
Plant Physiol. 98:790-791(1992) [PubMed: 16668715] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

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Cross-references

Sequence databases

M80597 mRNA. Translation: AAA32915.1. Sequence problems.
AF317553 mRNA. Translation: AAG31813.1.

3D structure databases

HSSPHSSP built from PDB template 1DBZ based on UniProtKB P46275.
ModBaseSearch...

Enzyme and pathway databases

BRENDA3.1.3.11. 124.

Family and domain databases

InterProIPR000146. Fructose_bisphosphatase.
IPR017955. IMPase/FBPase.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. FBPHPHTASE.
PR00377. INFBPHPHTASE.
ProDomPD001491. In_FB_phphtase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameF16P2_BETVU
AccessionPrimary (citable) accession number: Q42649
Secondary accession number(s): Q9FUA5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: September 27, 2005
Last modified: June 16, 2009
This is version 52 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents