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Reviewed, UniProtKB/Swiss-Prot Q42553 (IDI2_ARATH)

Last modified June 16, 2009. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Isopentenyl-diphosphate Delta-isomerase II
    EC=5.3.3.2
Alternative name(s):
    Isopentenyl pyrophosphate isomerase II
      Short name=IPP isomerase II
Gene names
Name: IPP2
Ordered Locus Names: At3g02780
ORF Names: F13E7.28
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length284 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) By similarity.

Catalytic activity

Isopentenyl diphosphate = dimethylallyl diphosphate.

Cofactor

Binds 1 magnesium ion per subunit By similarity.

Pathway

Isoprenoid biosynthesis; dimethylallyl-PP biosynthesis; dimethylallyl-PP from isopentenyl-PP: step 1/1.

Porphyrin biosynthesis; chlorophyll biosynthesis.

Sequence similarities

Belongs to the IPP isomerase type 1 family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 284284Isopentenyl-diphosphate Delta-isomerase II
PRO_0000205233

Sites

Active site1391 By similarity
Active site2011 By similarity
Metal binding921Magnesium By similarity
Metal binding1041Magnesium By similarity
Metal binding1991Magnesium By similarity
Metal binding2011Magnesium By similarity
Binding site881Substrate By similarity
Binding site1231Substrate By similarity
Binding site1271Substrate By similarity
Binding site1401Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q42553-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 614D02F354E242FF

FASTA28432,607
        10         20         30         40         50         60 
MSASSLFNLP LIRLRSLALS SSFSSFRFAH RPLSSISPRK LPNFRAFSGT AMTDTKDAGM 

        70         80         90        100        110        120 
DAVQRRLMFE DECILVDETD RVVGHDSKYN CHLMENIEAK NLLHRAFSVF LFNSKYELLL 

       130        140        150        160        170        180 
QQRSNTKVTF PLVWTNTCCS HPLYRESELI QDNALGVRNA AQRKLLDELG IVAEDVPVDE 

       190        200        210        220        230        240 
FTPLGRMLYK APSDGKWGEH ELDYLLFIVR DVKVQPNPDE VAEIKYVSRE ELKELVKKAD 

       250        260        270        280 
AGEEGLKLSP WFRLVVDNFL MKWWDHVEKG TLVEAIDMKT IHKL

« Hide

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References

« Hide 'large scale' references
[1]"Analysis of the isopentenyl diphosphate isomerase gene family from Arabidopsis thaliana."
Campbell M., Hahn F.M., Poulter C.D., Leustek T.
Plant Mol. Biol. 36:323-328(1998) [PubMed: 9484444] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed: 11130713] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

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Cross-references

Sequence databases

U49259 mRNA. Translation: AAC49920.1.
AC018363 Genomic DNA. Translation: AAF26982.1.
AF428343 mRNA. Translation: AAL16273.1.
AY127023 mRNA. Translation: AAM83247.1.
AY143845 mRNA. Translation: AAN28784.1.
IPIIPI00516444.
PIRS71370.
RefSeqNP_186927.1.
UniGeneAt.10819

3D structure databases

HSSPHSSP built from PDB template 1NFZ based on UniProtKB Q46822.
ModBaseSearch...

Proteomic databases

PRIDEQ42553.

Genome annotation databases

GeneID820960.
GenomeReviewsGene locus AT3G02780 in contig BA000014_GR.
KEGGath:AT3G02780.
NMPDRfig|3702.1.peg.12225.

Organism-specific databases

TAIRAt3g02780.

Phylogenomic databases

OMAQ42553. NENEVAE.

Enzyme and pathway databases

BioCycMetaCyc:AT3G02780-MON.
BRENDA5.3.3.2. 302.

Gene expression databases

ArrayExpressQ42553.
GermOnlineAT3G02780. Arabidopsis thaliana.

Family and domain databases

InterProIPR011876. IsopentenylPP_isomerase_typ1.
IPR000086. NUDIX_hydrolase_core.
[Graphical view]
Gene3DG3DSA:3.90.79.10. NUDIX_hydrolase. 1 hit.
PANTHERPTHR10885. IPP_isom_1. 1 hit.
PfamPF00293. NUDIX. 1 hit.
[Graphical view]
PIRSFPIRSF018427. Isopntndiph_ism. 1 hit.
ProDomPD004109. IPP_isomerase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR02150. IPP_isom_1. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameIDI2_ARATH
AccessionPrimary (citable) accession number: Q42553
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: June 16, 2009
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents