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Q42540

- UBC7_ARATH

UniProt

Q42540 - UBC7_ARATH

Protein

Ubiquitin-conjugating enzyme E2 7

Gene

UBC7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 113 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Involved in the formation of multiubiquitin chains. Signal the protein for selective degradation.1 Publication

    Catalytic activityi

    ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei89 – 891Glycyl thioester intermediatePROSITE-ProRule annotation

    GO - Molecular functioni

    1. acid-amino acid ligase activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Ubl conjugation pathway

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G59300-MONOMER.
    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin-conjugating enzyme E2 7 (EC:6.3.2.19)
    Alternative name(s):
    Ubiquitin carrier protein 7
    Ubiquitin-protein ligase 7
    Gene namesi
    Name:UBC7
    Ordered Locus Names:At5g59300
    ORF Names:MNC17.21
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G59300.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 166166Ubiquitin-conjugating enzyme E2 7PRO_0000082586Add
    BLAST

    Proteomic databases

    PaxDbiQ42540.
    PRIDEiQ42540.

    Expressioni

    Gene expression databases

    GenevestigatoriQ42540.

    Structurei

    3D structure databases

    ProteinModelPortaliQ42540.
    SMRiQ42540. Positions 5-164.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG5078.
    HOGENOMiHOG000233454.
    InParanoidiQ42540.
    KOiK10575.
    PhylomeDBiQ42540.

    Family and domain databases

    Gene3Di3.10.110.10. 1 hit.
    InterProiIPR000608. UBQ-conjugat_E2.
    IPR023313. UBQ-conjugating_AS.
    IPR016135. UBQ-conjugating_enzyme/RWD.
    [Graphical view]
    PfamiPF00179. UQ_con. 1 hit.
    [Graphical view]
    SUPFAMiSSF54495. SSF54495. 1 hit.
    PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
    PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q42540-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASQASLLLQ KQLKDLCKHP VDGFSAGLVD EKNIFEWSVT IIGPPDTLYE    50
    GGFFNAIMTF PQNYPNSPPT VRFTSDMWHP NVYSDGRVCI SILHPPGDDP 100
    SGYELASERW TPVHTVESIM LSIISMLSGP NDESPANVEA AKEWRDKRDE 150
    FKKKVSRCVR KSQEMF 166
    Length:166
    Mass (Da):18,722
    Last modified:November 1, 1996 - v1
    Checksum:i967EF672ADBD6891
    GO

    Sequence cautioni

    The sequence AAL86003.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AAO64200.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AED97168.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33757 Genomic DNA. Translation: AAC49321.1.
    AB016890 Genomic DNA. Translation: BAB09775.1.
    CP002688 Genomic DNA. Translation: AED97168.1. Different initiation.
    AY080733 mRNA. Translation: AAL86003.1. Different initiation.
    BT005798 mRNA. Translation: AAO64200.1. Different initiation.
    PIRiS71209.
    RefSeqiNP_568902.2. NM_125320.2.
    UniGeneiAt.43359.

    Genome annotation databases

    EnsemblPlantsiAT5G59300.1; AT5G59300.1; AT5G59300.
    GeneIDi836048.
    KEGGiath:AT5G59300.

    Cross-referencesi

    Web resourcesi

    PlantsUBQ

    A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U33757 Genomic DNA. Translation: AAC49321.1 .
    AB016890 Genomic DNA. Translation: BAB09775.1 .
    CP002688 Genomic DNA. Translation: AED97168.1 . Different initiation.
    AY080733 mRNA. Translation: AAL86003.1 . Different initiation.
    BT005798 mRNA. Translation: AAO64200.1 . Different initiation.
    PIRi S71209.
    RefSeqi NP_568902.2. NM_125320.2.
    UniGenei At.43359.

    3D structure databases

    ProteinModelPortali Q42540.
    SMRi Q42540. Positions 5-164.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q42540.
    PRIDEi Q42540.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G59300.1 ; AT5G59300.1 ; AT5G59300 .
    GeneIDi 836048.
    KEGGi ath:AT5G59300.

    Organism-specific databases

    TAIRi AT5G59300.

    Phylogenomic databases

    eggNOGi COG5078.
    HOGENOMi HOG000233454.
    InParanoidi Q42540.
    KOi K10575.
    PhylomeDBi Q42540.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .
    BioCyci ARA:AT5G59300-MONOMER.

    Gene expression databases

    Genevestigatori Q42540.

    Family and domain databases

    Gene3Di 3.10.110.10. 1 hit.
    InterProi IPR000608. UBQ-conjugat_E2.
    IPR023313. UBQ-conjugating_AS.
    IPR016135. UBQ-conjugating_enzyme/RWD.
    [Graphical view ]
    Pfami PF00179. UQ_con. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54495. SSF54495. 1 hit.
    PROSITEi PS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
    PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Arabidopsis thaliana UBC7/13/14 genes encode a family of multiubiquitin chain-forming E2 enzymes."
      van Nocker S., Walker J.M., Vierstra R.D.
      J. Biol. Chem. 271:12150-12158(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
      Strain: cv. Columbia.
      Tissue: Seedling.
    2. "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence features of the regions of 1,081,958 bp covered by seventeen physically assigned P1 and TAC clones."
      Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N., Tabata S.
      DNA Res. 5:379-391(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.

    Entry informationi

    Entry nameiUBC7_ARATH
    AccessioniPrimary (citable) accession number: Q42540
    Secondary accession number(s): F4KHV0, Q8RXQ3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 23, 2003
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 113 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3