Reviewed,
UniProtKB/Swiss-Prot Q42472 (DCE2_ARATH)
Last modified
February 9, 2010.
Version 64.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Glutamate decarboxylase 2 Short name=GAD 2 EC=4.1.1.15 | ||||||||
| Gene names |
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| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 494 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Catalyzes the production of GABA. The calmodulin-binding is calcium-dependent and it is proposed that this may, directly or indirectly, form a calcium regulated control of GABA biosynthesis By similarity. |
| Catalytic activity | L-glutamate = 4-aminobutanoate + CO2. |
| Cofactor | Pyridoxal phosphate. |
| Sequence similarities | Belongs to the group II decarboxylase family. |
Ontologies
| Keywords | |
|---|---|
| Coding sequence diversity | Alternative splicing |
| Ligand | Calmodulin-binding Pyridoxal phosphate |
| Molecular function | Decarboxylase Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glutamate metabolic process Ref.1 Inferred from direct assay. Source: TAIR |
| Molecular function | calmodulin binding Inferred from electronic annotation. Source: UniProtKB-KW glutamate decarboxylase activity Ref.1Inferred from direct assay. Source: TAIR pyridoxal phosphate bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Alternative products
| This entry describes 1 isoform produced by alternative splicing. [Select] Note: A number of isoforms are produced. According to EST sequences. | ||||||
| Isoform 1 (identifier: Q42472-1) This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. |
Sequence annotation (Features)
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U49937 mRNA. Translation: AAC31617.1. U46665 mRNA. Translation: AAC33485.1. AC009513 Genomic DNA. Translation: AAF06056.1. AF428372 mRNA. Translation: AAL16302.1. AY124873 mRNA. Translation: AAM70582.1. |
| IPI | IPI00534442. |
| PIR | H96683. |
| RefSeq | NP_001117556.1. |
| UniGene | At.19149 At.20543 At.24993 At.66846 Rra.1909 Rra.3867 Rra.851 Rsa.18186 Rsa.22073 Rsa.2344 |
3D structure databases | |
| SMR | Q42472. Positions 10-447. |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | Q42472. |
| ProMEX | Q42472. |
Genome annotation databases | |
| GeneID | 842908. |
| GenomeReviews | Gene locus AT1G65960 in contig CT485782_GR. |
| KEGG | ath:AT1G65960. |
| NMPDR | fig|3702.1.peg.6017. |
Organism-specific databases | |
| TAIR | At1g65960. |
Phylogenomic databases | |
| eggNOG | KOG1383. |
| HOGENOM | HBG365574. |
| InParanoid | Q42472. |
| PhylomeDB | Q42472. |
Enzyme and pathway databases | |
| BRENDA | 4.1.1.15. 302. |
Gene expression databases | |
| Genevestigator | Q42472. |
| GermOnline | AT1G65960. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view] |
| Gene3D | G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. |
| PANTHER | PTHR11999:SF1. Glu_decarb_GAD. 1 hit. PTHR11999. Pyridoxal_deC. 1 hit. |
| Pfam | PF00282. Pyridoxal_deC. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01788. Glu-decarb-GAD. 1 hit. |
| PROSITE | PS00392. DDC_GAD_HDC_YDC. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DCE2_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q42472 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


