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Reviewed, UniProtKB/Swiss-Prot Q42403 (TRXH3_ARATH)

Last modified December 16, 2008. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Thioredoxin H-type 3
      Short name=Trx-H-3
Gene names
Name: TRX3
Ordered Locus Names: At5g42980
ORF Names: MBD2.18
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length118 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The H form is known to activate a number of cytosolic enzymes By similarity.

Subcellular location

CytoplasmBy similarity.

Sequence similarities

Belongs to the thioredoxin family. Plant H-type subfamily.

Contains 1 thioredoxin domain.

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

O228701EBI-449157,EBI-449404
P284931EBI-449157,EBI-449524
P938191EBI-449157,EBI-449310
Q8L9K51EBI-449157,EBI-449250
Q8LCQ91EBI-449157,EBI-449272
Q8RWV01EBI-449157,EBI-449231
Q93Z051EBI-449157,EBI-449302
Q9FJY61EBI-449157,EBI-449539
Q9SAU21EBI-449157,EBI-449241
Q9XI011EBI-449157,EBI-449394
ALAAT1Q9LKJ41EBI-449157,EBI-449292
ALDH11A3Q1WIQ61EBI-449157,EBI-449197
ALEUQ8H1661EBI-449157,EBI-449450
APX1Q054311EBI-449157,EBI-449365
At1g09310Q9ZPZ41EBI-449157,EBI-449584
At1g32060P256971EBI-449157,EBI-449190
At1g43670Q9MA791EBI-449157,EBI-449204
At1g65930Q9SRZ61EBI-449157,EBI-449319
At2g47400/T8I13.24O229141EBI-449157,EBI-449213
At3g18490Q8RXI11EBI-449157,EBI-449501
At3g23940Q94BS61EBI-449157,EBI-449458
At3g55800P462831EBI-449157,EBI-449184
AT4g26530O655811EBI-449157,EBI-449257
At5g16705Q8LE521EBI-449157,EBI-449357
At5g53490P817601EBI-449157,EBI-449573
CA1P271401EBI-449157,EBI-449468
CA2P427371EBI-449157,EBI-449490
CAD1P427341EBI-449157,EBI-449530
CYP20-3P347911EBI-449157,EBI-449385
F8J2_100Q9LF981EBI-449157,EBI-449265
FD1O040901EBI-449157,EBI-449441
FD2P169721EBI-449157,EBI-449431
GDCSHP258551EBI-449157,EBI-449563
GLN2Q431271EBI-449157,EBI-449283
GST6Q962661EBI-449157,EBI-449374
LPD1Q9M5K31EBI-449157,EBI-449547
NIR1Q391611EBI-449157,EBI-449330
PMSRP541501EBI-449157,EBI-449349
PRXIIEQ949U71EBI-449157,EBI-449344
PSBO1P233211EBI-449157,EBI-449414
PSBO2Q9S8411EBI-449157,EBI-449424
RCAP108961EBI-449157,EBI-449165
T12C14_110Q9LZP91EBI-449157,EBI-449218
TGG1P377021EBI-449157,EBI-449510
TIMQ9SKP61EBI-449157,EBI-449224

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 118118Thioredoxin H-type 3
PRO_0000120048

Regions

Domain2 – 113112Thioredoxin

Amino acid modifications

Disulfide bond39 ↔ 42Redox-active By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q42403-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7AFCE291C3EB8FE2

FASTA11813,109
        10         20         30         40         50         60 
MAAEGEVIAC HTVEDWTEKL KAANESKKLI VIDFTATWCP PCRFIAPVFA DLAKKHLDVV 

        70         80         90        100        110 
FFKVDVDELN TVAEEFKVQA MPTFIFMKEG EIKETVVGAA KEEIIANLEK HKTVVAAA

« Hide

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References

« Hide 'large scale' references
[1]"Evidence for five divergent thioredoxin h sequences in Arabidopsis thaliana."
Rivera-Madrid R., Mestres D., Marinho P., Jacquot J.-P., Decottignies P., Miginiac-Maslow M., Meyer Y.
Proc. Natl. Acad. Sci. U.S.A. 92:5620-5624(1995) [PubMed: 7777559] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: cv. Columbia.
Tissue: Callus.
[2]"Intron position as an evolutionary marker of thioredoxins and thioredoxin domains."
Sahrawy M., Hecht V., Lopez Jaramillo J., Chueca A., Chartier Y., Meyer Y.
J. Mol. Evol. 42:422-431(1996) [PubMed: 8642611] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Landsberg erecta.
[3]"Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence features of the regions of 1,191,918 bp covered by seventeen physically assigned P1 clones."
Nakamura Y., Sato S., Kaneko T., Kotani H., Asamizu E., Miyajima N., Tabata S.
DNA Res. 4:401-414(1997) [PubMed: 9501997] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[6]"Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs."
Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C., Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R., Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J. expand/collapse author list , Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D., Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P., Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H.
Plant J. 9:101-124(1996) [PubMed: 8580968] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 33-105.
Strain: cv. Columbia.

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Cross-references

Sequence databases

Z35474 mRNA. Translation: CAA84611.1.
U35640 Genomic DNA. Translation: AAC49351.1.
AB008264 Genomic DNA. Translation: BAB09200.1.
AY059870 mRNA. Translation: AAL24352.1.
AY065098 mRNA. Translation: AAL38274.1.
AY093318 mRNA. Translation: AAM13317.1.
AY114566 mRNA. Translation: AAM47885.1.
AY085117 mRNA. Translation: AAM61671.1.
Z35335 mRNA. Translation: CAA84560.1.
PIRS58118.
RefSeqNP_199112.1.
UniGeneAt.24175

3D structure databases

HSSPHSSP built from PDB template 1EP7 based on UniProtKB P80028.
ModBaseSearch...

Protein-protein interaction databases

IntActQ42403. 50 interactions.

Proteomic databases

PRIDEQ42403.

Genome annotation databases

GeneID834313.
GenomeReviewsGene locus AT5G42980 in contig BA000015_GR.
KEGGath:AT5G42980.
NMPDRfig|3702.1.peg.26032.

Organism-specific databases

TAIRAt5g42980.

Gene expression databases

ArrayExpressQ42403.
GermOnlineAT5G42980. Arabidopsis thaliana.

Family and domain databases

InterProIPR006662. Thioredoxin-like.
IPR013766. Thioredoxin_dom.
IPR012335. Thioredoxin_fold.
IPR015467. Trx.
[Graphical view]
Gene3DG3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PANTHERPTHR10438. Trx. 1 hit.
PfamPF00085. Thioredoxin. 1 hit.
[Graphical view]
PRINTSPR00421. THIOREDOXIN.
PROSITEPS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameTRXH3_ARATH
AccessionPrimary (citable) accession number: Q42403
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: December 16, 2008
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents