Q42377 (EC2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
EC protein homolog 2

Gene names

Ordered Locus Names:	At2g23240
ORF Names:	T20D16.13

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	85 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Binds 5 molecules of zinc. May have a role in Zn2+ homeostasis during embryogenesis By similarity.
Sequence similarities	Belongs to the metallothionein superfamily. Type 15 family.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Ligand	Metal-binding Metal-thiolate cluster Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	zinc ion transport Inferred from mutant phenotype PubMed 22014117. Source: TAIR
Cellular_component	cytoplasm Inferred from direct assay PubMed 22014117. Source: TAIR membrane Inferred from direct assay PubMed 22014117. Source: TAIR nucleus Inferred from direct assay PubMed 22014117. Source: TAIR
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q42377-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 85	85	EC protein homolog 2		PRO_0000197424

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 1, 2000. Version 2. Checksum: 3B4065F1CD427912	FASTA	85	8,437
	10 20 30 40 50 60 MADTGKGSAS ASCNDRCGCP SPCPGGESCR CKMMSEASGG DQEHNTCPCG EHCGCNPCNC 70 80 PKTQTQTSAK GCTCGEGCTC ATCAA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C. Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs." Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C., Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R., Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J. , Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D., Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P., Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H. Plant J. 9:101-124(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-85. Strain: cv. Columbia. Tissue: Dry seed.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC002391 Genomic DNA. Translation: AAB87107.1. CP002685 Genomic DNA. Translation: AEC07432.1. Z27049 mRNA. Translation: CAA81575.1. Z29896 mRNA. Translation: CAA82835.1.
IPI	IPI00548215.
PIR	T00508.
RefSeq	NP_179905.1. NM_127888.1.
UniGene	At.39319.
3D structure databases
ProteinModelPortal	Q42377.
SMR	Q42377. Positions 43-85.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT2G23240.1-P.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT2G23240.1; AT2G23240.1; AT2G23240.
GeneID	816856.
KEGG	ath:AT2G23240.
Organism-specific databases
TAIR	At2g23240.
Phylogenomic databases
eggNOG	NOG304685.
HOGENOM	HOG000243560.
InParanoid	Q42377.
OMA	CNCASCA.
PhylomeDB	Q42377.
ProtClustDB	CLSN2683807.
Gene expression databases
ArrayExpress	Q42377.
Genevestigator	Q42377.
Family and domain databases
InterPro	IPR000316. Metallthion_15. [Graphical view]
Pfam	PF02068. Metallothio_PEC. 1 hit. [Graphical view]
PRINTS	PR00877. MTPLANTPEC.
ProtoNet	Search...

Entry information

Entry name

EC2_ARATH

Accession

Primary (citable) accession number: Q42377
Secondary accession number(s): Q9SLN4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	December 1, 2000
Last modified:	May 1, 2013
This is version 82 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program