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Protein

Syntaxin-related protein KNOLLE

Gene

KN

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in cytokinesis. Acts as a cell plate-specific syntaxin, required for the fusion of vesicles at the plane of cell division.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-449836 Other interleukin signaling

Protein family/group databases

TCDBi8.A.91.1.1 the syntaxin (syntaxin) family

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-related protein KNOLLE
Alternative name(s):
Syntaxin-111
Short name:
AtSYP111
Gene namesi
Name:KN
Synonyms:SYP111
Ordered Locus Names:At1g08560
ORF Names:F22O13.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G08560
TAIRilocus:2025620 AT1G08560

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 283CytoplasmicSequence analysisAdd BLAST283
Transmembranei284 – 304Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini305 – 310VesicularSequence analysis6

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002102441 – 310Syntaxin-related protein KNOLLEAdd BLAST310

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ42374

PTM databases

iPTMnetiQ42374

Expressioni

Tissue specificityi

Abundant in flowers and developing siliques. A low level expression is seen in the seedlings, roots, and leaves.

Developmental stagei

It is detected throughout embryogenesis until expression declines in mature embryo. During embryogenesis it is detected in patches of single cells or small cell groups.

Inductioni

At or soon after the onset of mitosis.

Gene expression databases

ExpressionAtlasiQ42374 baseline and differential
GenevisibleiQ42374 AT

Interactioni

Subunit structurei

Interacts with SNAP33 and/or NPSN11 to form a t-SNARE complex and with KEULE.3 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi22619, 27 interactors
IntActiQ42374, 22 interactors
MINTiQ42374
STRINGi3702.AT1G08560.1

Structurei

3D structure databases

ProteinModelPortaliQ42374
SMRiQ42374
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini212 – 274t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili94 – 159Sequence analysisAdd BLAST66

Sequence similaritiesi

Belongs to the syntaxin family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0810 Eukaryota
COG5074 LUCA
HOGENOMiHOG000238904
InParanoidiQ42374
KOiK08486
OMAiGEHPDEE
OrthoDBiEOG09360O8W
PhylomeDBiQ42374

Family and domain databases

InterProiView protein in InterPro
IPR010989 SNARE
IPR006012 Syntaxin/epimorphin_CS
IPR006011 Syntaxin_N
IPR000727 T_SNARE_dom
PfamiView protein in Pfam
PF05739 SNARE, 1 hit
PF00804 Syntaxin, 1 hit
SMARTiView protein in SMART
SM00503 SynN, 1 hit
SM00397 t_SNARE, 1 hit
SUPFAMiSSF47661 SSF47661, 1 hit
PROSITEiView protein in PROSITE
PS00914 SYNTAXIN, 1 hit
PS50192 T_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

Q42374-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDLMTKSFM SYVDLKKAAM KDMEAGPDFD LEMASTKADK MDENLSSFLE
60 70 80 90 100
EAEYVKAEMG LISETLARIE QYHEESKGVH KAESVKSLRN KISNEIVSGL
110 120 130 140 150
RKAKSIKSKL EEMDKANKEI KRLSGTPVYR SRTAVTNGLR KKLKEVMMEF
160 170 180 190 200
QGLRQKMMSE YKETVERRYF TVTGEHANDE MIEKIITDNA GGEEFLTRAI
210 220 230 240 250
QEHGKGKVLE TVVEIQDRYD AAKEIEKSLL ELHQVFLDMA VMVESQGEQM
260 270 280 290 300
DEIEHHVINA SHYVADGANE LKTAKSHQRN SRKWMCIGII VLLLIILIVV
310
IPIITSFSSS
Length:310
Mass (Da):35,275
Last modified:November 1, 1996 - v1
Checksum:iF97909E27835DD87
GO

Sequence cautioni

The sequence AAF99783 differs from that shown. Reason: Frameshift at position 250.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39452 Genomic DNA Translation: AAC49163.1
U39451 mRNA Translation: AAC49162.1
AC003981 Genomic DNA Translation: AAF99783.1 Frameshift.
CP002684 Genomic DNA Translation: AEE28306.1
BT000970 mRNA Translation: AAN41370.1
PIRiD86218
T00709
RefSeqiNP_172332.1, NM_100729.4
UniGeneiAt.10802

Genome annotation databases

EnsemblPlantsiAT1G08560.1; AT1G08560.1; AT1G08560
GeneIDi837378
GrameneiAT1G08560.1; AT1G08560.1; AT1G08560
KEGGiath:AT1G08560

Similar proteinsi

Entry informationi

Entry nameiSY111_ARATH
AccessioniPrimary (citable) accession number: Q42374
Secondary accession number(s): Q8VXY8, Q9FRS8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health