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Protein

Syntaxin-related protein KNOLLE

Gene

KN

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in cytokinesis. Acts as a cell plate-specific syntaxin, required for the fusion of vesicles at the plane of cell division.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-449147. Signaling by Interleukins.

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-related protein KNOLLE
Alternative name(s):
Syntaxin-111
Short name:
AtSYP111
Gene namesi
Name:KN
Synonyms:SYP111
Ordered Locus Names:At1g08560
ORF Names:F22O13.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G08560.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 283283CytoplasmicSequence analysisAdd
BLAST
Transmembranei284 – 30421Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini305 – 3106VesicularSequence analysis

GO - Cellular componenti

  • cell plate Source: TAIR
  • endomembrane system Source: TAIR
  • integral component of membrane Source: GO_Central
  • phragmoplast Source: TAIR
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
  • SNARE complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 310310Syntaxin-related protein KNOLLEPRO_0000210244Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ42374.
PRIDEiQ42374.

PTM databases

iPTMnetiQ42374.

Expressioni

Tissue specificityi

Abundant in flowers and developing siliques. A low level expression is seen in the seedlings, roots, and leaves.

Developmental stagei

It is detected throughout embryogenesis until expression declines in mature embryo. During embryogenesis it is detected in patches of single cells or small cell groups.

Inductioni

At or soon after the onset of mitosis.

Gene expression databases

GenevisibleiQ42374. AT.

Interactioni

Subunit structurei

Interacts with SNAP33 and/or NPSN11 to form a t-SNARE complex and with KEULE.3 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi22619. 27 interactions.
IntActiQ42374. 22 interactions.
MINTiMINT-7712575.
STRINGi3702.AT1G08560.1.

Structurei

3D structure databases

ProteinModelPortaliQ42374.
SMRiQ42374. Positions 42-303.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini212 – 27463t-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili94 – 15966Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the syntaxin family.Curated
Contains 1 t-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0810. Eukaryota.
COG5074. LUCA.
HOGENOMiHOG000238904.
InParanoidiQ42374.
KOiK08486.
OMAiIEHHVIN.
OrthoDBiEOG09360O8W.
PhylomeDBiQ42374.

Family and domain databases

InterProiIPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PfamiPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTiSM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q42374-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDLMTKSFM SYVDLKKAAM KDMEAGPDFD LEMASTKADK MDENLSSFLE
60 70 80 90 100
EAEYVKAEMG LISETLARIE QYHEESKGVH KAESVKSLRN KISNEIVSGL
110 120 130 140 150
RKAKSIKSKL EEMDKANKEI KRLSGTPVYR SRTAVTNGLR KKLKEVMMEF
160 170 180 190 200
QGLRQKMMSE YKETVERRYF TVTGEHANDE MIEKIITDNA GGEEFLTRAI
210 220 230 240 250
QEHGKGKVLE TVVEIQDRYD AAKEIEKSLL ELHQVFLDMA VMVESQGEQM
260 270 280 290 300
DEIEHHVINA SHYVADGANE LKTAKSHQRN SRKWMCIGII VLLLIILIVV
310
IPIITSFSSS
Length:310
Mass (Da):35,275
Last modified:November 1, 1996 - v1
Checksum:iF97909E27835DD87
GO

Sequence cautioni

The sequence AAF99783 differs from that shown. Reason: Frameshift at position 250. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39452 Genomic DNA. Translation: AAC49163.1.
U39451 mRNA. Translation: AAC49162.1.
AC003981 Genomic DNA. Translation: AAF99783.1. Frameshift.
CP002684 Genomic DNA. Translation: AEE28306.1.
BT000970 mRNA. Translation: AAN41370.1.
PIRiD86218.
T00709.
RefSeqiNP_172332.1. NM_100729.3.
UniGeneiAt.10802.

Genome annotation databases

EnsemblPlantsiAT1G08560.1; AT1G08560.1; AT1G08560.
GeneIDi837378.
GrameneiAT1G08560.1; AT1G08560.1; AT1G08560.
KEGGiath:AT1G08560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39452 Genomic DNA. Translation: AAC49163.1.
U39451 mRNA. Translation: AAC49162.1.
AC003981 Genomic DNA. Translation: AAF99783.1. Frameshift.
CP002684 Genomic DNA. Translation: AEE28306.1.
BT000970 mRNA. Translation: AAN41370.1.
PIRiD86218.
T00709.
RefSeqiNP_172332.1. NM_100729.3.
UniGeneiAt.10802.

3D structure databases

ProteinModelPortaliQ42374.
SMRiQ42374. Positions 42-303.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi22619. 27 interactions.
IntActiQ42374. 22 interactions.
MINTiMINT-7712575.
STRINGi3702.AT1G08560.1.

PTM databases

iPTMnetiQ42374.

Proteomic databases

PaxDbiQ42374.
PRIDEiQ42374.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G08560.1; AT1G08560.1; AT1G08560.
GeneIDi837378.
GrameneiAT1G08560.1; AT1G08560.1; AT1G08560.
KEGGiath:AT1G08560.

Organism-specific databases

TAIRiAT1G08560.

Phylogenomic databases

eggNOGiKOG0810. Eukaryota.
COG5074. LUCA.
HOGENOMiHOG000238904.
InParanoidiQ42374.
KOiK08486.
OMAiIEHHVIN.
OrthoDBiEOG09360O8W.
PhylomeDBiQ42374.

Enzyme and pathway databases

ReactomeiR-ATH-449147. Signaling by Interleukins.

Miscellaneous databases

PROiQ42374.

Gene expression databases

GenevisibleiQ42374. AT.

Family and domain databases

InterProiIPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PfamiPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTiSM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSY111_ARATH
AccessioniPrimary (citable) accession number: Q42374
Secondary accession number(s): Q8VXY8, Q9FRS8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.