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Protein

Defensin-like protein 195

Gene

ATTI1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei48 – 49Reactive bondBy similarity2

GO - Molecular functioni

  • ion channel inhibitor activity Source: InterPro
  • serine-type endopeptidase inhibitor activity Source: TAIR

GO - Biological processi

  • defense response Source: TAIR
  • defense response to fungus Source: TAIR
  • killing of cells of other organism Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Fungicide

Keywords - Biological processi

Plant defense

Protein family/group databases

MEROPSiI18.001.

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-like protein 195
Alternative name(s):
ATTp
Trypsin inhibitor ATTI-1
diDi 4T-1
Gene namesi
Name:ATTI1
Ordered Locus Names:At2g43510
ORF Names:T01O24.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G43510.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000003109328 – 89Defensin-like protein 195Add BLAST62

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi32 ↔ 841 Publication
Disulfide bondi45 ↔ 691 Publication
Disulfide bondi54 ↔ 791 Publication
Disulfide bondi58 ↔ 811 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ42328.

Expressioni

Gene expression databases

GenevisibleiQ42328. AT.

Interactioni

Protein-protein interaction databases

BioGridi4288. 4 interactors.
IntActiQ42328. 7 interactors.
STRINGi3702.AT2G43510.1.

Structurei

Secondary structure

189
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni42 – 44Combined sources3
Helixi53 – 61Combined sources9
Beta strandi65 – 69Combined sources5
Beta strandi74 – 77Combined sources4
Beta strandi79 – 83Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JXCNMR-A22-89[»]
ProteinModelPortaliQ42328.
SMRiQ42328.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ42328.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JS1T. Eukaryota.
ENOG4111CSI. LUCA.
HOGENOMiHOG000090027.
InParanoidiQ42328.
OMAiEAQGNEC.
OrthoDBiEOG09360WS9.
PhylomeDBiQ42328.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR003614. Scorpion_toxin-like.
IPR002061. Scorpion_toxinL/defensin.
[Graphical view]
PfamiPF00537. Toxin_3. 1 hit.
[Graphical view]
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q42328-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKAIVSIFV VFFIFFLVIS DVPEIEAQGN ECLKEYGGDV GFGFCAPRIF
60 70 80
PTICYTRCRE NKGAKGGRCR WGQGSNVKCL CDFCDDTPQ
Length:89
Mass (Da):9,885
Last modified:January 10, 2003 - v3
Checksum:iC4FA5D0B3ABB03D5
GO

Sequence cautioni

The sequence CAA86849 differs from that shown. Reason: Frameshift at positions 10, 12, 15 and 23.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti85D → G in CAA86849 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti6V → I in strain: cv. Goe-0. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46816 mRNA. Translation: CAA86849.1. Frameshift.
AJ249958 mRNA. Translation: CAB62548.1.
AJ632250 Genomic DNA. Translation: CAG15155.1.
AJ632251 Genomic DNA. Translation: CAG15160.1.
AJ632252 Genomic DNA. Translation: CAG15165.1.
AJ632253 Genomic DNA. Translation: CAG15170.1.
AJ632254 Genomic DNA. Translation: CAG15175.1.
AJ632255 Genomic DNA. Translation: CAG15181.1.
AJ632256 Genomic DNA. Translation: CAG15187.1.
AJ632257 Genomic DNA. Translation: CAG15193.1.
AJ632258 Genomic DNA. Translation: CAG15198.1.
AJ632259 Genomic DNA. Translation: CAG15203.1.
AJ632260 Genomic DNA. Translation: CAG15208.1.
AJ632261 Genomic DNA. Translation: CAG15213.1.
AJ632262 Genomic DNA. Translation: CAG15218.1.
AJ632263 Genomic DNA. Translation: CAG15223.1.
AJ632264 Genomic DNA. Translation: CAG15228.1.
AJ632265 Genomic DNA. Translation: CAG15233.1.
AJ632266 Genomic DNA. Translation: CAG15238.1.
AC002335 Genomic DNA. Translation: AAB64325.1.
CP002685 Genomic DNA. Translation: AEC10284.1.
AY050789 mRNA. Translation: AAK92724.1.
AY096456 mRNA. Translation: AAM20096.1.
PIRiA84867.
RefSeqiNP_181879.1. NM_129912.4.
UniGeneiAt.10318.

Genome annotation databases

EnsemblPlantsiAT2G43510.1; AT2G43510.1; AT2G43510.
GeneIDi818952.
GrameneiAT2G43510.1; AT2G43510.1; AT2G43510.
KEGGiath:AT2G43510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46816 mRNA. Translation: CAA86849.1. Frameshift.
AJ249958 mRNA. Translation: CAB62548.1.
AJ632250 Genomic DNA. Translation: CAG15155.1.
AJ632251 Genomic DNA. Translation: CAG15160.1.
AJ632252 Genomic DNA. Translation: CAG15165.1.
AJ632253 Genomic DNA. Translation: CAG15170.1.
AJ632254 Genomic DNA. Translation: CAG15175.1.
AJ632255 Genomic DNA. Translation: CAG15181.1.
AJ632256 Genomic DNA. Translation: CAG15187.1.
AJ632257 Genomic DNA. Translation: CAG15193.1.
AJ632258 Genomic DNA. Translation: CAG15198.1.
AJ632259 Genomic DNA. Translation: CAG15203.1.
AJ632260 Genomic DNA. Translation: CAG15208.1.
AJ632261 Genomic DNA. Translation: CAG15213.1.
AJ632262 Genomic DNA. Translation: CAG15218.1.
AJ632263 Genomic DNA. Translation: CAG15223.1.
AJ632264 Genomic DNA. Translation: CAG15228.1.
AJ632265 Genomic DNA. Translation: CAG15233.1.
AJ632266 Genomic DNA. Translation: CAG15238.1.
AC002335 Genomic DNA. Translation: AAB64325.1.
CP002685 Genomic DNA. Translation: AEC10284.1.
AY050789 mRNA. Translation: AAK92724.1.
AY096456 mRNA. Translation: AAM20096.1.
PIRiA84867.
RefSeqiNP_181879.1. NM_129912.4.
UniGeneiAt.10318.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JXCNMR-A22-89[»]
ProteinModelPortaliQ42328.
SMRiQ42328.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4288. 4 interactors.
IntActiQ42328. 7 interactors.
STRINGi3702.AT2G43510.1.

Protein family/group databases

MEROPSiI18.001.

Proteomic databases

PaxDbiQ42328.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G43510.1; AT2G43510.1; AT2G43510.
GeneIDi818952.
GrameneiAT2G43510.1; AT2G43510.1; AT2G43510.
KEGGiath:AT2G43510.

Organism-specific databases

TAIRiAT2G43510.

Phylogenomic databases

eggNOGiENOG410JS1T. Eukaryota.
ENOG4111CSI. LUCA.
HOGENOMiHOG000090027.
InParanoidiQ42328.
OMAiEAQGNEC.
OrthoDBiEOG09360WS9.
PhylomeDBiQ42328.

Miscellaneous databases

EvolutionaryTraceiQ42328.
PROiQ42328.

Gene expression databases

GenevisibleiQ42328. AT.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR003614. Scorpion_toxin-like.
IPR002061. Scorpion_toxinL/defensin.
[Graphical view]
PfamiPF00537. Toxin_3. 1 hit.
[Graphical view]
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDF195_ARATH
AccessioniPrimary (citable) accession number: Q42328
Secondary accession number(s): O22865, Q6ZZP6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 10, 2003
Last modified: November 30, 2016
This is version 117 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

Was (Ref. 1, PubMed:15082560 and PubMed:12369816) thought to be a protease inhibitor.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.