Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q42059

- GUN6_ARATH

UniProt

Q42059 - GUN6_ARATH

Protein

Endoglucanase 6

Gene

At1g64390

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 2 (05 Sep 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei411 – 4111By similarity
    Active sitei463 – 4631By similarity
    Active sitei472 – 4721By similarity

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    BioCyciARA:AT1G64390-MONOMER.

    Protein family/group databases

    CAZyiCBM49. Carbohydrate-Binding Module Family 49.
    GH9. Glycoside Hydrolase Family 9.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase 6 (EC:3.2.1.4)
    Alternative name(s):
    Endo-1,4-beta glucanase 6
    Gene namesi
    Ordered Locus Names:At1g64390
    ORF Names:F15H21.9
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G64390.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 620598Endoglucanase 6PRO_0000249259Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi554 – 5541N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi564 – 5641N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ42059.
    PRIDEiQ42059.

    Expressioni

    Gene expression databases

    GenevestigatoriQ42059.

    Structurei

    3D structure databases

    ProteinModelPortaliQ42059.
    SMRiQ42059. Positions 24-490.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG05134.
    HOGENOMiHOG000021033.
    InParanoidiQ42059.
    OMAiYRYSTIV.
    PhylomeDBiQ42059.

    Family and domain databases

    Gene3Di1.50.10.10. 1 hit.
    InterProiIPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR019028. CBM_49.
    IPR001701. Glyco_hydro_9.
    IPR018221. Glyco_hydro_9_AS.
    [Graphical view]
    PfamiPF09478. CBM49. 1 hit.
    PF00759. Glyco_hydro_9. 1 hit.
    [Graphical view]
    SMARTiSM01063. CBM49. 1 hit.
    [Graphical view]
    SUPFAMiSSF48208. SSF48208. 1 hit.
    PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
    PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q42059-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEKFAPVAAL LLLLLCFPVA FSGHDYGQAL SKSLLFFEAQ RSGVLPRNQR    50
    VTWRSHSGLT DGKSSGVNLV GGYYDAGDNV KFGLPMAFTV TMMAWSVIEY 100
    GNQLQANGEL GNSIDAIKWG TDYFIKAHPE PNVLYGEVGD GNTDHYCWQR 150
    PEEMTTDRKA YRIDPSNPGS DLAGETAAAM AAASIVFRRS NPVYSRLLLT 200
    HAYQLFDFAD KYRGKYDSSI TVAQKYYRSV SGYNDELLWA AAWLYQASNN 250
    QFYLDYLGRN GDAMGGTGWS MTEFGWDVKY AGVQTLVAKF LMQGKAGRHA 300
    PVFRKYQEKA DSFMCSLLGK SSRNIQKTPG GLIFRQRWNN MQFVTSASFL 350
    TTVYSDYLTS SRSNLRCAAG NVAPSQLLSF AKSQVDYILG DNPRATSYMV 400
    GYGNNFPQRV HHRGSSIVSV KVDRTFVTCR GGYATWFSRK GSDPNLLTGA 450
    IVGGPDAYDN FADRRDNYEQ TEPATYNNAP LLGVLARLSS GHSGYSQFLP 500
    VVPAPVVRRP MPIRRPKVTT PVRASGPVAI VQKITSSWVS KGRTYYRYST 550
    TVINKSSRPL KSLNLSIKNL YGPIWGLSRS GNSFGLPSWM HSLPSGKSLE 600
    FVYIHSTTPA NVAVSSYTLA 620
    Length:620
    Mass (Da):68,592
    Last modified:September 5, 2006 - v2
    Checksum:i57847AE1990D427F
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti196 – 1961R → K in AAN31840. (PubMed:14593172)Curated
    Sequence conflicti442 – 4421S → V in CAA81116. (PubMed:8580968)Curated
    Sequence conflicti511 – 5144MPIR → NAYS in CAA81116. (PubMed:8580968)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC066689 Genomic DNA. Translation: AAG51703.1.
    CP002684 Genomic DNA. Translation: AEE34236.1.
    AF372940 mRNA. Translation: AAK50080.1.
    AY143945 mRNA. Translation: AAN28884.1.
    BT000696 mRNA. Translation: AAN31840.1.
    Z25957 mRNA. Translation: CAA81116.1.
    PIRiA96668.
    RefSeqiNP_176621.1. NM_105114.2.
    UniGeneiAt.17827.
    At.37005.
    At.72671.

    Genome annotation databases

    EnsemblPlantsiAT1G64390.1; AT1G64390.1; AT1G64390.
    GeneIDi842747.
    KEGGiath:AT1G64390.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC066689 Genomic DNA. Translation: AAG51703.1 .
    CP002684 Genomic DNA. Translation: AEE34236.1 .
    AF372940 mRNA. Translation: AAK50080.1 .
    AY143945 mRNA. Translation: AAN28884.1 .
    BT000696 mRNA. Translation: AAN31840.1 .
    Z25957 mRNA. Translation: CAA81116.1 .
    PIRi A96668.
    RefSeqi NP_176621.1. NM_105114.2.
    UniGenei At.17827.
    At.37005.
    At.72671.

    3D structure databases

    ProteinModelPortali Q42059.
    SMRi Q42059. Positions 24-490.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi CBM49. Carbohydrate-Binding Module Family 49.
    GH9. Glycoside Hydrolase Family 9.

    Proteomic databases

    PaxDbi Q42059.
    PRIDEi Q42059.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G64390.1 ; AT1G64390.1 ; AT1G64390 .
    GeneIDi 842747.
    KEGGi ath:AT1G64390.

    Organism-specific databases

    TAIRi AT1G64390.

    Phylogenomic databases

    eggNOGi NOG05134.
    HOGENOMi HOG000021033.
    InParanoidi Q42059.
    OMAi YRYSTIV.
    PhylomeDBi Q42059.

    Enzyme and pathway databases

    BioCyci ARA:AT1G64390-MONOMER.

    Gene expression databases

    Genevestigatori Q42059.

    Family and domain databases

    Gene3Di 1.50.10.10. 1 hit.
    InterProi IPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR019028. CBM_49.
    IPR001701. Glyco_hydro_9.
    IPR018221. Glyco_hydro_9_AS.
    [Graphical view ]
    Pfami PF09478. CBM49. 1 hit.
    PF00759. Glyco_hydro_9. 1 hit.
    [Graphical view ]
    SMARTi SM01063. CBM49. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48208. SSF48208. 1 hit.
    PROSITEi PS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
    PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 397-514.
      Strain: cv. Columbia.
      Tissue: Shoot.
    5. "Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
      Libertini E., Li Y., McQueen-Mason S.J.
      J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.

    Entry informationi

    Entry nameiGUN6_ARATH
    AccessioniPrimary (citable) accession number: Q42059
    Secondary accession number(s): Q8H160, Q9C7W3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 106 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3