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Q42059 (GUN6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 105. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase 6

EC=3.2.1.4
Alternative name(s):
Endo-1,4-beta glucanase 6
Gene names
Ordered Locus Names:At1g64390
ORF Names:F15H21.9
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length620 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 9 (cellulase E) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cell wall biogenesis/degradation
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncarbohydrate binding

Inferred from electronic annotation. Source: InterPro

cellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 620598Endoglucanase 6
PRO_0000249259

Sites

Active site4111 By similarity
Active site4631 By similarity
Active site4721 By similarity

Amino acid modifications

Glycosylation5541N-linked (GlcNAc...) Potential
Glycosylation5641N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict1961R → K in AAN31840. Ref.3
Sequence conflict4421S → V in CAA81116. Ref.4
Sequence conflict511 – 5144MPIR → NAYS in CAA81116. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q42059 [UniParc].

Last modified September 5, 2006. Version 2.
Checksum: 57847AE1990D427F

FASTA62068,592
        10         20         30         40         50         60 
MEKFAPVAAL LLLLLCFPVA FSGHDYGQAL SKSLLFFEAQ RSGVLPRNQR VTWRSHSGLT 

        70         80         90        100        110        120 
DGKSSGVNLV GGYYDAGDNV KFGLPMAFTV TMMAWSVIEY GNQLQANGEL GNSIDAIKWG 

       130        140        150        160        170        180 
TDYFIKAHPE PNVLYGEVGD GNTDHYCWQR PEEMTTDRKA YRIDPSNPGS DLAGETAAAM 

       190        200        210        220        230        240 
AAASIVFRRS NPVYSRLLLT HAYQLFDFAD KYRGKYDSSI TVAQKYYRSV SGYNDELLWA 

       250        260        270        280        290        300 
AAWLYQASNN QFYLDYLGRN GDAMGGTGWS MTEFGWDVKY AGVQTLVAKF LMQGKAGRHA 

       310        320        330        340        350        360 
PVFRKYQEKA DSFMCSLLGK SSRNIQKTPG GLIFRQRWNN MQFVTSASFL TTVYSDYLTS 

       370        380        390        400        410        420 
SRSNLRCAAG NVAPSQLLSF AKSQVDYILG DNPRATSYMV GYGNNFPQRV HHRGSSIVSV 

       430        440        450        460        470        480 
KVDRTFVTCR GGYATWFSRK GSDPNLLTGA IVGGPDAYDN FADRRDNYEQ TEPATYNNAP 

       490        500        510        520        530        540 
LLGVLARLSS GHSGYSQFLP VVPAPVVRRP MPIRRPKVTT PVRASGPVAI VQKITSSWVS 

       550        560        570        580        590        600 
KGRTYYRYST TVINKSSRPL KSLNLSIKNL YGPIWGLSRS GNSFGLPSWM HSLPSGKSLE 

       610        620 
FVYIHSTTPA NVAVSSYTLA 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Further progress towards a catalogue of all Arabidopsis genes: analysis of a set of 5000 non-redundant ESTs."
Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C., Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R., Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J. expand/collapse author list , Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D., Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P., Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H.
Plant J. 9:101-124(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 397-514.
Strain: cv. Columbia.
Tissue: Shoot.
[5]"Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
Libertini E., Li Y., McQueen-Mason S.J.
J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC066689 Genomic DNA. Translation: AAG51703.1.
CP002684 Genomic DNA. Translation: AEE34236.1.
AF372940 mRNA. Translation: AAK50080.1.
AY143945 mRNA. Translation: AAN28884.1.
BT000696 mRNA. Translation: AAN31840.1.
Z25957 mRNA. Translation: CAA81116.1.
PIRA96668.
RefSeqNP_176621.1. NM_105114.2.
UniGeneAt.17827.
At.37005.
At.72671.

3D structure databases

ProteinModelPortalQ42059.
SMRQ42059. Positions 24-490.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyCBM49. Carbohydrate-Binding Module Family 49.
GH9. Glycoside Hydrolase Family 9.

Proteomic databases

PaxDbQ42059.
PRIDEQ42059.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G64390.1; AT1G64390.1; AT1G64390.
GeneID842747.
KEGGath:AT1G64390.

Organism-specific databases

TAIRAT1G64390.

Phylogenomic databases

eggNOGNOG05134.
HOGENOMHOG000021033.
InParanoidQ42059.
OMAYRYSTIV.
PhylomeDBQ42059.

Enzyme and pathway databases

BioCycARA:AT1G64390-MONOMER.

Gene expression databases

GenevestigatorQ42059.

Family and domain databases

Gene3D1.50.10.10. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR019028. CBM_49.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamPF09478. CBM49. 1 hit.
PF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SMARTSM01063. CBM49. 1 hit.
[Graphical view]
SUPFAMSSF48208. SSF48208. 1 hit.
PROSITEPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
PS00698. GLYCOSYL_HYDROL_F9_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN6_ARATH
AccessionPrimary (citable) accession number: Q42059
Secondary accession number(s): Q8H160, Q9C7W3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names