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Protein

Defensin-like protein 4

Gene

PDF2.1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Confers broad-spectrum resistance to pathogens.

GO - Biological processi

  • defense response Source: TAIR
  • defense response to fungus Source: UniProtKB-KW
  • killing of cells of other organism Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Fungicide

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-like protein 4
Alternative name(s):
Low-molecular-weight cysteine-rich protein 70
Short name:
Protein LCR70
Plant defensin 2.1
Gene namesi
Name:PDF2.1
Synonyms:LCR70
Ordered Locus Names:At2g02120
ORF Names:F5O4.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G02120.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence analysisAdd
BLAST
Chaini31 – 7747Defensin-like protein 4PRO_0000007025Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi33 ↔ 77By similarity
Disulfide bondi44 ↔ 64By similarity
Disulfide bondi50 ↔ 71By similarity
Disulfide bondi54 ↔ 73By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ41914.
PRIDEiQ41914.

Expressioni

Tissue specificityi

Expressed in roots, siliques and seeds.1 Publication

Gene expression databases

GenevisibleiQ41914. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G02120.1.

Structurei

3D structure databases

ProteinModelPortaliQ41914.
SMRiQ41914. Positions 30-77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DEFL family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J2FQ. Eukaryota.
ENOG410YXD4. LUCA.
HOGENOMiHOG000238637.
InParanoidiQ41914.
OMAiRRRCFCA.
PhylomeDBiQ41914.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008177. G_Purothionin.
IPR008176. Gamma-thionin.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PRINTSiPR00288. PUROTHIONIN.
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q41914-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFSMRLISA VLFLVMIFVA TGMGPVTVEA RTCASQSQRF KGKCVSDTNC
60 70
ENVCHNEGFP GGDCRGFRRR CFCTRNC
Length:77
Mass (Da):8,578
Last modified:December 1, 2000 - v2
Checksum:iFB7BE5AF727A9A45
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti19 – 191V → D in CAA79029 (PubMed:8281187).Curated
Sequence conflicti69 – 691R → G in CAA79029 (PubMed:8281187).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005936 Genomic DNA. Translation: AAC97222.1.
CP002685 Genomic DNA. Translation: AEC05548.1.
AK117966 mRNA. Translation: BAC42603.1.
BT004647 mRNA. Translation: AAO42893.1.
Z17665 mRNA. Translation: CAA79029.1.
PIRiB84433.
RefSeqiNP_178320.1. NM_126272.3.
UniGeneiAt.42941.

Genome annotation databases

EnsemblPlantsiAT2G02120.1; AT2G02120.1; AT2G02120.
GeneIDi814743.
GrameneiAT2G02120.1; AT2G02120.1; AT2G02120.
KEGGiath:AT2G02120.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005936 Genomic DNA. Translation: AAC97222.1.
CP002685 Genomic DNA. Translation: AEC05548.1.
AK117966 mRNA. Translation: BAC42603.1.
BT004647 mRNA. Translation: AAO42893.1.
Z17665 mRNA. Translation: CAA79029.1.
PIRiB84433.
RefSeqiNP_178320.1. NM_126272.3.
UniGeneiAt.42941.

3D structure databases

ProteinModelPortaliQ41914.
SMRiQ41914. Positions 30-77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G02120.1.

Proteomic databases

PaxDbiQ41914.
PRIDEiQ41914.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G02120.1; AT2G02120.1; AT2G02120.
GeneIDi814743.
GrameneiAT2G02120.1; AT2G02120.1; AT2G02120.
KEGGiath:AT2G02120.

Organism-specific databases

TAIRiAT2G02120.

Phylogenomic databases

eggNOGiENOG410J2FQ. Eukaryota.
ENOG410YXD4. LUCA.
HOGENOMiHOG000238637.
InParanoidiQ41914.
OMAiRRRCFCA.
PhylomeDBiQ41914.

Miscellaneous databases

PROiQ41914.

Gene expression databases

GenevisibleiQ41914. AT.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008177. G_Purothionin.
IPR008176. Gamma-thionin.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PRINTSiPR00288. PUROTHIONIN.
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
    Tissue: Green siliques.
  6. "Tissue-specific expression of plant defensin genes PDF2.1 and PDF2.2 in Arabidopsis thaliana."
    Thomma B.P.H.J., Broekaert W.F.
    Plant Physiol. Biochem. 36:533-537(1998)
    Cited for: TISSUE SPECIFICITY.
  7. "Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response."
    Vanoosthuyse V., Miege C., Dumas C., Cock J.M.
    Plant Mol. Biol. 46:17-34(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  8. Cited for: GENE FAMILY, NOMENCLATURE.
  9. "Genome organization of more than 300 defensin-like genes in Arabidopsis."
    Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.
    Plant Physiol. 138:600-610(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiDEF04_ARATH
AccessioniPrimary (citable) accession number: Q41914
Secondary accession number(s): Q541X5, Q9ZUL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: February 17, 2016
This is version 112 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.