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Protein

Defensin-like protein 4

Gene

PDF2.1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Confers broad-spectrum resistance to pathogens.

GO - Biological processi

  • defense response Source: TAIR
  • defense response to fungus Source: UniProtKB-KW
  • killing of cells of other organism Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Fungicide

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-like protein 4
Alternative name(s):
Low-molecular-weight cysteine-rich protein 70
Short name:
Protein LCR70
Plant defensin 2.1
Gene namesi
Name:PDF2.1
Synonyms:LCR70
Ordered Locus Names:At2g02120
ORF Names:F5O4.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G02120.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence analysisAdd
BLAST
Chaini31 – 7747Defensin-like protein 4PRO_0000007025Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi33 ↔ 77By similarity
Disulfide bondi44 ↔ 64By similarity
Disulfide bondi50 ↔ 71By similarity
Disulfide bondi54 ↔ 73By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ41914.
PRIDEiQ41914.

Expressioni

Tissue specificityi

Expressed in roots, siliques and seeds.1 Publication

Gene expression databases

GenevisibleiQ41914. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G02120.1.

Structurei

3D structure databases

ProteinModelPortaliQ41914.
SMRiQ41914. Positions 30-77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DEFL family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J2FQ. Eukaryota.
ENOG410YXD4. LUCA.
HOGENOMiHOG000238637.
InParanoidiQ41914.
OMAiIVEARTC.
OrthoDBiEOG09360Y66.
PhylomeDBiQ41914.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008176. Defensin_plant.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PRINTSiPR00288. PUROTHIONIN.
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q41914-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFSMRLISA VLFLVMIFVA TGMGPVTVEA RTCASQSQRF KGKCVSDTNC
60 70
ENVCHNEGFP GGDCRGFRRR CFCTRNC
Length:77
Mass (Da):8,578
Last modified:December 1, 2000 - v2
Checksum:iFB7BE5AF727A9A45
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti19 – 191V → D in CAA79029 (PubMed:8281187).Curated
Sequence conflicti69 – 691R → G in CAA79029 (PubMed:8281187).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005936 Genomic DNA. Translation: AAC97222.1.
CP002685 Genomic DNA. Translation: AEC05548.1.
AK117966 mRNA. Translation: BAC42603.1.
BT004647 mRNA. Translation: AAO42893.1.
Z17665 mRNA. Translation: CAA79029.1.
PIRiB84433.
RefSeqiNP_178320.1. NM_126272.3.
UniGeneiAt.42941.

Genome annotation databases

EnsemblPlantsiAT2G02120.1; AT2G02120.1; AT2G02120.
GeneIDi814743.
GrameneiAT2G02120.1; AT2G02120.1; AT2G02120.
KEGGiath:AT2G02120.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005936 Genomic DNA. Translation: AAC97222.1.
CP002685 Genomic DNA. Translation: AEC05548.1.
AK117966 mRNA. Translation: BAC42603.1.
BT004647 mRNA. Translation: AAO42893.1.
Z17665 mRNA. Translation: CAA79029.1.
PIRiB84433.
RefSeqiNP_178320.1. NM_126272.3.
UniGeneiAt.42941.

3D structure databases

ProteinModelPortaliQ41914.
SMRiQ41914. Positions 30-77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G02120.1.

Proteomic databases

PaxDbiQ41914.
PRIDEiQ41914.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G02120.1; AT2G02120.1; AT2G02120.
GeneIDi814743.
GrameneiAT2G02120.1; AT2G02120.1; AT2G02120.
KEGGiath:AT2G02120.

Organism-specific databases

TAIRiAT2G02120.

Phylogenomic databases

eggNOGiENOG410J2FQ. Eukaryota.
ENOG410YXD4. LUCA.
HOGENOMiHOG000238637.
InParanoidiQ41914.
OMAiIVEARTC.
OrthoDBiEOG09360Y66.
PhylomeDBiQ41914.

Miscellaneous databases

PROiQ41914.

Gene expression databases

GenevisibleiQ41914. AT.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008176. Defensin_plant.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PRINTSiPR00288. PUROTHIONIN.
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDEF04_ARATH
AccessioniPrimary (citable) accession number: Q41914
Secondary accession number(s): Q541X5, Q9ZUL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: September 7, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.