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Protein

Aquaporin PIP1-1

Gene

PIP1-1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Water channel required to facilitate the transport of water across cell membrane. Active as heteromers with PIP1-2, but not as homomers.1 Publication

GO - Molecular functioni

GO - Biological processi

  • protein heterotetramerization Source: AgBase
  • protein homotetramerization Source: AgBase

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Aquaporin PIP1-1
Alternative name(s):
Plasma membrane intrinsic protein 1-1
ZmPIP1-1
ZmPIP1;1
ZmPIP1a
Gene namesi
Name:PIP1-1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei57 – 77Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei92 – 114Helical; Name=2Sequence analysisAdd BLAST23
Transmembranei134 – 154Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei176 – 196Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei210 – 230Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei258 – 278Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi245V → I: Active as heteromers with PIP2-5; when associated with R-249; D-250 and N-254. 1 Publication1
Mutagenesisi249Q → R: Active as heteromers with PIP2-5; when associated with V-245; D-250 and N-254. 1 Publication1
Mutagenesisi250H → D: Active as heteromers with PIP2-5; when associated with V-245; R-249; and N-254. 1 Publication1
Mutagenesisi254A → N: Active as heteromers with PIP2-5; when associated with V-245; R-249 and D-250. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002860131 – 287Aquaporin PIP1-1Add BLAST287

Proteomic databases

PRIDEiQ41870

Expressioni

Tissue specificityi

Highly expressed in roots, shoots and developing tassels, and at lower levels in leaves.1 Publication

Inductioni

Expressed in roots with a circadian rhythm showing an increase at the end of the night period, a peak during the first part of the light period and then a decrease.1 Publication

Gene expression databases

ExpressionAtlasiQ41870 differential

Interactioni

Subunit structurei

May interact with PIP1-2 to form heteromers.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ41870
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi115 – 117NPA 1By similarity3
Motifi236 – 238NPA 2By similarity3

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0223 Eukaryota
COG0580 LUCA

Family and domain databases

CDDicd00333 MIP, 1 hit
Gene3Di1.20.1080.10, 1 hit
InterProiView protein in InterPro
IPR023271 Aquaporin-like
IPR034294 Aquaporin_transptr
IPR000425 MIP
IPR022357 MIP_CS
PANTHERiPTHR19139 PTHR19139, 1 hit
PfamiView protein in Pfam
PF00230 MIP, 1 hit
PRINTSiPR00783 MINTRINSICP
SUPFAMiSSF81338 SSF81338, 1 hit
TIGRFAMsiTIGR00861 MIP, 1 hit
PROSITEiView protein in PROSITE
PS00221 MIP, 1 hit

Sequencei

Sequence statusi: Complete.

Q41870-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGKEEDVRL GANKFSERHA IGTAAQGTDD KDYKEPPPAP LFEPGELKSW
60 70 80 90 100
SFYRPGIAEF VATFLFLYIS ILTVMGVSKS TSKCATVGIQ GIAWSFGGMI
110 120 130 140 150
LALVYCTAGI SGHINPAVTF GLFLARKLSL TRAVFYIIMQ CLGAICGRGV
160 170 180 190 200
VKGFQQGLYM GNGGRRNVVA PGYTKGDGLG AEIVGTFILV YTVFSATDAK
210 220 230 240 250
RRARDSHVPI LAPLPIGFAV FLVHLATMGI TGTGINPARS LGAAVIYNQH
260 270 280
HAWADHWIFW VGPFIGAALA AIYHQVIIRA IPFKSRS
Length:287
Mass (Da):30,885
Last modified:November 1, 1996 - v1
Checksum:i0F46696F5D64FA47
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X82633 mRNA Translation: CAA57955.1
PIRiS60455
UniGeneiZm.160910
Zm.181

Similar proteinsi

Entry informationi

Entry nameiPIP11_MAIZE
AccessioniPrimary (citable) accession number: Q41870
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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