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Protein

ADP,ATP carrier protein 2, mitochondrial

Gene

ANT-G2

Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei104ADPBy similarity1
Binding sitei116ADPBy similarity1
Binding sitei261ADPBy similarity1

GO - Molecular functioni

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 2, mitochondrial
Alternative name(s):
ADP/ATP translocase 2
Adenine nucleotide translocator 2
Short name:
ANT 2
Gene namesi
Name:ANT-G2
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 58Helical; Name=1By similarityAdd BLAST28
Transmembranei99 – 123Helical; Name=2By similarityAdd BLAST25
Transmembranei132 – 152Helical; Name=3By similarityAdd BLAST21
Transmembranei202 – 223Helical; Name=4By similarityAdd BLAST22
Transmembranei237 – 257Helical; Name=5By similarityAdd BLAST21
Transmembranei297 – 317Helical; Name=6By similarityAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000019254? – 331ADP,ATP carrier protein 2, mitochondrial
Transit peptidei1 – ?Mitochondrion

Proteomic databases

PRIDEiQ41630

Expressioni

Gene expression databases

ExpressionAtlasiQ41630 baseline and differential

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ41630
SMRiQ41630
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati29 – 122Solcar 1Add BLAST94
Repeati134 – 226Solcar 2Add BLAST93
Repeati238 – 320Solcar 3Add BLAST83

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni261 – 266Important for transport activityBy similarity6

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi261 – 266Nucleotide carrier signature motifBy similarity6

Domaini

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. At least 2 of the odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.By similarity

Sequence similaritiesi

Keywords - Domaini

Repeat, Transit peptide, Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002113 Aden_trnslctor
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00927 ADPTRNSLCASE
PR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q41630-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQNLGISVP MMSSSPLFAN APPEKKGVKN FAIDFLMGGV SAAVSKTAAA
60 70 80 90 100
PIERVKLLIQ NQDEMIKAGR LSEPYKGIGD CFGRTIKDEG FGSLWRGNTA
110 120 130 140 150
NVIRYFPTQA LNFAFKDYFK RMFNFKKDKD GYWKWFGGNL ASGGAAGASS
160 170 180 190 200
LFFVYSLDYG RTRLANDAKA SKGGGDRQFN GLVDVYRKTL KSDGIAGLYR
210 220 230 240 250
GFNISCVGII VYRGLYFGLY DSLKPVLLTG TLQVCSFASF ALGWLITNGA
260 270 280 290 300
GLASYPIDTV RRRMMMTSGE AVKYKSSLDA FQQIPAKEGA KSLFKGAGAN
310 320 330
ILRAIAGAGV LSGYDQLQIL FFGKKYGSGG A
Length:331
Mass (Da):35,790
Last modified:November 1, 1996 - v1
Checksum:i265DE6AA41557908
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95864 Genomic DNA Translation: CAA65120.1

Similar proteinsi

Entry informationi

Entry nameiADT2_WHEAT
AccessioniPrimary (citable) accession number: Q41630
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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