Reviewed, UniProtKB/Swiss-Prot Q41578 (PORA_WHEAT)

Names and origin

Protein names

Recommended name:
    Protochlorophyllide reductase A, chloroplastic
      Short name=PCR A
    EC=1.3.1.33
Alternative name(s):
    NADPH-protochlorophyllide oxidoreductase A
      Short name=POR A

Gene names

Name:

PORA

Organism

Triticum aestivum (Wheat)

Taxonomic identifier

4565 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
Catalytic activity	Chlorophyllide a + NADP+ = protochlorophyllide + NADPH.
Pathway	Porphyrin biosynthesis; chlorophyll biosynthesis.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.

Ontologies

Keywords
Biological process	Chlorophyll biosynthesis Photosynthesis
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	NADP
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW photosynthesis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	binding Inferred from electronic annotation. Source: InterPro protochlorophyllide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 74	74	Chloroplast By similarity
	Chain	75 – 388	314	Protochlorophyllide reductase A, chloroplastic		PRO_0000023297

Sequences

	Sequence		Length	Mass (Da)
	Q41578-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 86B9DB96BD085AB3	FASTA	388	41,156
	10 20 30 40 50 60 MALQLLPSTL SVPKKGSSMG AAAVKDTAAF LGVSSKAKKA SLAVRTQVAT APSSVTTSPG 70 80 90 100 110 120 SATAKPSGKK TLRQGVVVIT GASSGLGLAA AKALAETGKW HVVMACRDFL KASKAAKAAG 130 140 150 160 170 180 MADGSYTVMH LDLASLDSVR QFVDAFRRAE MPLDVLVCNA AIYRPTARTP TFTADGHEMS 190 200 210 220 230 240 VGVNHLGHFL LARLLMEDLQ KSDYPSRRMV IVGSITGNSN TLAGNVPPKA SLGDLRGLAG 250 260 270 280 290 300 GLSGASGSAM IDGDESFDGA KAYKDSKVCN MLTMQEFHRR YHEETGITFS SLYPGCIATT 310 320 330 340 350 360 GLFREHIPLF RTLFPPFQKF VTKGFVSEAE SGKRLAQVVA EPSLTKSGVY WSWNKDSASF 370 380 ENQLSQEASD PEKARKVWEL SEKLVGLA

References

[1]	"Cloning, characterization and import studies on protochlorophyllide reductase from wheat (Triticum aestivum)." Teakle G.R., Griffiths W.T. Biochem. J. 296:225-230(1993) [PubMed: 8250847] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Tissue: Shoot.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X76532 Genomic DNA. Translation: CAA54042.1.
PIR	S39394.
3D structure databases
HSSP	HSSP built from PDB template 1FDS based on UniProtKB P14061.
ModBase	Search...
Organism-specific databases
Gramene	Q41578.
Enzyme and pathway databases
BRENDA	1.3.1.33. 253.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR005979. Prochl_reduct. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR19410. ADH_short_C2. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR00081. GDHRDH.
TIGRFAMs	TIGR01289. LPOR. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PORA_WHEAT

Accession

Primary (citable) accession number: Q41578

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)