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Q41436

- CHSA_SOLTU

UniProt

Q41436 - CHSA_SOLTU

Protein

Chalcone synthase 1A

Gene

CHS1A

Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    • Comment

    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase 1A (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase 1A
    Gene namesi
    Name:CHS1A
    OrganismiSolanum tuberosum (Potato)
    Taxonomic identifieri4113 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
    ProteomesiUP000011115: Unplaced

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 389389Chalcone synthase 1APRO_0000216052Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ41436.
    SMRiQ41436. Positions 3-388.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Phylogenomic databases

    KOiK00660.

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q41436-1 [UniParc]FASTAAdd to Basket

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    MVTVEEYRKA QRAEGPATIL AIGTSTPSNC VDQSTYPDYY FRITNSEHKT    50
    ELKEKFKRMC DKSMIKKRYM HLTEEILKEN PNMCAYMAPS LDARQDIVVV 100
    EVPKLGKEAA QKAIKEWGQP KSKITHLVFC TTSGVDMPGC DYQLAKLLGL 150
    RPSVKRLMMY QQGCFVGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG 200
    PSESHLDSLV GQALFGDGAA AIIMGSDPII GVERPLFELV SAAQTLVPDS 250
    EGAIDGHLRE VGLTFHLLKD VPGLISKNIE KSLLEAFQPL GISDWNSLFW 300
    IAHPGGPAIL DQVELKLGLK QEKLRATREV LSNYGNMSSA CVLFILDEMR 350
    KASTNEGLGT TGEGLEWGVL FGFGPGLTVE TVVLHSVAT 389
    Length:389
    Mass (Da):42,562
    Last modified:November 1, 1996 - v1
    Checksum:iB181D9C6B9170A34
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U47739 mRNA. Translation: AAB67734.1.
    RefSeqiNP_001275352.1. NM_001288423.1.
    UniGeneiStu.186.

    Genome annotation databases

    GeneIDi102577871.
    KEGGisot:102577871.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U47739 mRNA. Translation: AAB67734.1 .
    RefSeqi NP_001275352.1. NM_001288423.1.
    UniGenei Stu.186.

    3D structure databases

    ProteinModelPortali Q41436.
    SMRi Q41436. Positions 3-388.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 102577871.
    KEGGi sot:102577871.

    Phylogenomic databases

    KOi K00660.

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of two members of the chalcone synthase gene family from Solanum tuberosum L."
      Jeon J.-H., Kim H.-S., Choi K.-H., Joung Y.-H., Joung H., Byun S.-M.
      Plant Gene Register PGR96-027
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Red Pontiac.

    Entry informationi

    Entry nameiCHSA_SOLTU
    AccessioniPrimary (citable) accession number: Q41436
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1999
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3