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Q41436

- CHSA_SOLTU

UniProt

Q41436 - CHSA_SOLTU

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Protein
Chalcone synthase 1A
Gene
CHS1A
Organism
Solanum tuberosum (Potato)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 1A (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 1A
Gene namesi
Name:CHS1A
OrganismiSolanum tuberosum (Potato)
Taxonomic identifieri4113 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanum
ProteomesiUP000011115: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Chalcone synthase 1A
PRO_0000216052Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ41436.
SMRiQ41436. Positions 3-388.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00660.

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q41436-1 [UniParc]FASTAAdd to Basket

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MVTVEEYRKA QRAEGPATIL AIGTSTPSNC VDQSTYPDYY FRITNSEHKT    50
ELKEKFKRMC DKSMIKKRYM HLTEEILKEN PNMCAYMAPS LDARQDIVVV 100
EVPKLGKEAA QKAIKEWGQP KSKITHLVFC TTSGVDMPGC DYQLAKLLGL 150
RPSVKRLMMY QQGCFVGGTV LRLAKDLAEN NKGARVLVVC SEITAVTFRG 200
PSESHLDSLV GQALFGDGAA AIIMGSDPII GVERPLFELV SAAQTLVPDS 250
EGAIDGHLRE VGLTFHLLKD VPGLISKNIE KSLLEAFQPL GISDWNSLFW 300
IAHPGGPAIL DQVELKLGLK QEKLRATREV LSNYGNMSSA CVLFILDEMR 350
KASTNEGLGT TGEGLEWGVL FGFGPGLTVE TVVLHSVAT 389
Length:389
Mass (Da):42,562
Last modified:November 1, 1996 - v1
Checksum:iB181D9C6B9170A34
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U47739 mRNA. Translation: AAB67734.1.
RefSeqiNP_001275352.1. NM_001288423.1.
UniGeneiStu.186.

Genome annotation databases

GeneIDi102577871.
KEGGisot:102577871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U47739 mRNA. Translation: AAB67734.1 .
RefSeqi NP_001275352.1. NM_001288423.1.
UniGenei Stu.186.

3D structure databases

ProteinModelPortali Q41436.
SMRi Q41436. Positions 3-388.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 102577871.
KEGGi sot:102577871.

Phylogenomic databases

KOi K00660.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterization of two members of the chalcone synthase gene family from Solanum tuberosum L."
    Jeon J.-H., Kim H.-S., Choi K.-H., Joung Y.-H., Joung H., Byun S.-M.
    Plant Gene Register PGR96-027
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Red Pontiac.

Entry informationi

Entry nameiCHSA_SOLTU
AccessioniPrimary (citable) accession number: Q41436
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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