Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q41342

- ETR1_SOLLC

UniProt

Q41342 - ETR1_SOLLC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ethylene receptor 1

Gene

ETR1

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.By similarity

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

Cofactori

Cu cationBy similarityNote: Binds 1 copper ion per dimer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi80 – 801CopperBy similarity
Metal bindingi84 – 841CopperBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. phosphorelay sensor kinase activity Source: InterPro

GO - Biological processi

  1. ethylene-activated signaling pathway Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Transferase

Keywords - Biological processi

Ethylene signaling pathway, Two-component regulatory system

Keywords - Ligandi

ATP-binding, Copper, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ethylene receptor 1 (EC:2.7.13.3)
Short name:
LeETR1
Gene namesi
Name:ETR1
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
ProteomesiUP000004994: Chromosome 12

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei38 – 5821HelicalSequence AnalysisAdd
BLAST
Transmembranei68 – 8821HelicalSequence AnalysisAdd
BLAST
Transmembranei108 – 12821HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum membrane Source: InterPro
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 754754Ethylene receptor 1PRO_0000081416Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi18 – 18InterchainBy similarity
Disulfide bondi20 – 20InterchainBy similarity
Modified residuei367 – 3671Phosphohistidine; by autocatalysisPROSITE-ProRule annotation
Modified residuei677 – 67714-aspartylphosphatePROSITE-ProRule annotation

Post-translational modificationi

Activation probably requires a transfer of a phosphate group between a His in the transmitter domain and an Asp of the receiver domain.By similarity

Keywords - PTMi

Disulfide bond, Phosphoprotein

Expressioni

Tissue specificityi

Leaves, flowers and fruits.

Developmental stagei

Expressed at all stages.

Inductioni

Constitutively expressed and accumulation not affected by ethylene, silver ions or auxin.

Interactioni

Subunit structurei

Homodimer; disulfide-linked.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
int106B6GVA22EBI-2407792,EBI-2407896

Protein-protein interaction databases

IntActiQ41342. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ41342.
SMRiQ41342. Positions 624-753.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini173 – 321149GAFAdd
BLAST
Domaini364 – 601238Histidine kinasePROSITE-ProRule annotationAdd
BLAST
Domaini629 – 746118Response regulatoryPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ethylene receptor family.Curated
Contains 1 GAF domain.Curated
Contains 1 histidine kinase domain.PROSITE-ProRule annotation
Contains 1 response regulatory domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ41342.
KOiK14509.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR004358. Sig_transdc_His_kin-like_C.
IPR014525. Sig_transdc_His_kin_hyb_Et-sen.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PIRSFiPIRSF026389. Ethyln_sen_HK. 1 hit.
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q41342-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSLLRMNRL LSSIVESCNC IIDPQLPADD LLMKYQYISD FFIALAYFSI
60 70 80 90 100
PVELIYFVKK SAVFPYRWVL VQFGAFIVLC GATHLINLWT FNMHTRNVAI
110 120 130 140 150
VMTTPKALTA LVSCITALML VHIIPDLLSV KTRELFLKKK AAQLDREMGI
160 170 180 190 200
IRTQEETGRH VRMLTHEIRS TLDRHTILKT TLVELGRTLA LEECALWMPT
210 220 230 240 250
RTGLELQLSY TLRHQNPVGL TVPIQLPVIN QVFGTNHVVK ISPNSPVARL
260 270 280 290 300
RPAGKYMPGE VVAVRVPLLH LSNFQINDWP ELSTKRYALM VLMLPSDSAR
310 320 330 340 350
QWHVHELELV EVVADQVAVA LSHAAILEES MRARDLLMEQ NVALDLARRE
360 370 380 390 400
AEMAVRARND FLAVMNHEMR TPMHAIIALS SLLQETDLTP EQRLMVETIL
410 420 430 440 450
KSSNLLATLI NDVLDLSRLE DGSLQLDIGT FNLHALFREV HSLIKPIASV
460 470 480 490 500
KKLFVTLSLS SDLPEYVIGD EKRLMQILLN VVGNAVKFSK EGNVSISAFV
510 520 530 540 550
AKSDSLRDPR APEFFAVPSE NHFYLRVQIK DTGIGITPQD IPNLFSKFTQ
560 570 580 590 600
SQALATTNSG GTGLGLAICK RFVNLMEGHI WIESEGLGKG STAIFIIKLG
610 620 630 640 650
IPGRANESKL PFVTKLPANH TQMSFQGLKV LVMDENGVSR MVTKGLLTHL
660 670 680 690 700
GCDVTTVGSR DECLRVVTHE HKVVIMDVSM QGIDCYEVAV VIHERFGKRH
710 720 730 740 750
GRPLIVALTG NTDRVTKENC MRVGMDGVIL KPVSVYKMRS VLSELLEHGV

VLES
Length:754
Mass (Da):84,202
Last modified:November 1, 1996 - v1
Checksum:iD7443B6517781D0A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti105 – 1051P → A in AAC02213. (PubMed:9721682)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41103 mRNA. Translation: AAA85479.1.
AF043084 mRNA. Translation: AAC02213.1.
PIRiS71783.
T52288.
RefSeqiNP_001234149.1. NM_001247220.1.
UniGeneiLes.3490.

Genome annotation databases

EnsemblPlantsiSolyc12g011330.2.1; Solyc12g011330.2.1; Solyc12g011330.2.
GeneIDi606298.
KEGGisly:606298.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41103 mRNA. Translation: AAA85479.1 .
AF043084 mRNA. Translation: AAC02213.1 .
PIRi S71783.
T52288.
RefSeqi NP_001234149.1. NM_001247220.1.
UniGenei Les.3490.

3D structure databases

ProteinModelPortali Q41342.
SMRi Q41342. Positions 624-753.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q41342. 2 interactions.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi Solyc12g011330.2.1 ; Solyc12g011330.2.1 ; Solyc12g011330.2 .
GeneIDi 606298.
KEGGi sly:606298.

Phylogenomic databases

InParanoidi Q41342.
KOi K14509.

Family and domain databases

Gene3Di 1.10.287.130. 1 hit.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
InterProi IPR011006. CheY-like_superfamily.
IPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR004358. Sig_transdc_His_kin-like_C.
IPR014525. Sig_transdc_His_kin_hyb_Et-sen.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view ]
Pfami PF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view ]
PIRSFi PIRSF026389. Ethyln_sen_HK. 1 hit.
PRINTSi PR00344. BCTRLSENSOR.
SMARTi SM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00448. REC. 1 hit.
[Graphical view ]
SUPFAMi SSF47384. SSF47384. 1 hit.
SSF52172. SSF52172. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEi PS50109. HIS_KIN. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The mRNA for an ETR1 homologue in tomato is constitutively expressed in vegetative and reproductive tissues."
    Zhou D., Kalaitzis P., Mattoo A.K., Tucker M.L.
    Plant Mol. Biol. 30:1331-1338(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Rutgers.
    Tissue: Abscission zone and Fruit.
  2. "Differential regulation of the tomato ETR gene family throughout plant development."
    Lashbrook C.C., Tieman D.M., Klee H.J.
    Plant J. 15:243-252(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Rutgers.
    Tissue: Root.

Entry informationi

Entry nameiETR1_SOLLC
AccessioniPrimary (citable) accession number: Q41342
Secondary accession number(s): O49186
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3