Q41290 (Q41290_SORBI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Dhurrinase EMBL AAC49177.1
Organism	Sorghum bicolor (Sorghum) (Sorghum vulgare) EMBL AAC49177.1
Taxonomic identifier	4558 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogoneae › Sorghum

Protein attributes

Sequence length	565 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 1 family. RuleBase RU003690

Ontologies

Keywords
Molecular function	Glycosidase RuleBase RU004468 Hydrolase
Technical term	3D-structure PDB 1V03 PDB 1V02
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q41290 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 29DCFAC3665C9809	FASTA	565	63,780
	10 20 30 40 50 60 MALLLASAIN HTAHPAGLRS HPNNESFSRH HLCSSPQNIS KRRSNLSFRP RAQTISSESA 70 80 90 100 110 120 GIHRLSPWEI PRRDWFPPSF LFGAATSAYQ IEGAWNEDGK GPSTWDHFCH NFPEWIVDRS 130 140 150 160 170 180 NGDVAADSYH MYAEDVRLLK EMGMDAYRFS ISWPRILPKG TLAGGINEKG VEYYNKLIDL 190 200 210 220 230 240 LLENGIEPYI TIFHWDTPQA LVDAYGGFLD EEDYKDYTDF AKVCFEKFGK TVKNWLTFNE 250 260 270 280 290 300 PETFCSVSYG TGVLAPGRCS PGVSCAVPTG NSLSEPYIVA HNLLRAHAET VDIYNKYHKG 310 320 330 340 350 360 ADGRIGLALN VFGRVPYTNT FLDQQAQERS MDKCLGWFLE PVVRGDYPFS MRVSARDRVP 370 380 390 400 410 420 YFKEKEQEKL VGSYDMIGIN YYTSTFSKHI DLSPNNSPVL NTDDAYASQE TKGPDGNAIG 430 440 450 460 470 480 PPTGNAWINM YPKGLHDILM TMKNKYGNPP MYITENGMGD IDKGDLPKPV ALEDHTRLDY 490 500 510 520 530 540 IQRHLSVLKQ SIDLGADVRG YFAWSLLDNF EWSSGYTERF GIVYVDRENG CERTMKRSAR 550 560 WLQEFNGAAK KVENNKILTP AGQLN

References

[1]	"Cloning and Sequencing of a cDNA Coding for Beta-Glucosidase (Dhurrinase) from Sorghum bicolor (L) Moench 1 (Accession No. U33817) (PGR95-097)." Cicek M., Esen A. Plant Physiol. 109:1497-1497(1995) [PubMed: 8539300] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: P721N EMBL AAC49177.1. Tissue: Etiolated shoots EMBL AAC49177.1.
[2]	"Structural determinants of substrate specificity in family 1 beta-glucosidases: novel insights from the crystal structure of sorghum dhurrinase-1, a plant beta-glucosidase with strict specificity, in complex with its natural substrate." Verdoucq L., Moriniere J., Bevan D.R., Esen A., Vasella A., Henrissat B., Czjzek M. J. Biol. Chem. 279:31796-31803(2004) [PubMed: 15148317] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U33817 mRNA. Translation: AAC49177.1.

PIR

T14732.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1V02	X-ray	1.80	A/B/C/D/E/F	1-565	[»]
1V03	X-ray	2.00	A	1-565	[»]

ProteinModelPortal

Q41290.

SMR

Q41290. Positions 64-547.

ModBase

Search...

Protein family/group databases

CAZy

GH1. Glycoside Hydrolase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Organism-specific databases

Gramene

Q41290.

Phylogenomic databases

GeneTree

EPGT00070000027915.

Family and domain databases

InterPro

IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

Gene3D

G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.

PANTHER

PTHR10353. Glyco_hydro_1. 1 hit.

Pfam

PF00232. Glyco_hydro_1. 1 hit.
[Graphical view]

PRINTS

PR00131. GLHYDRLASE1.

SUPFAM

SSF51445. Glyco_hydro_cat. 1 hit.

PROSITE

PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q41290_SORBI

Accession

Primary (citable) accession number: Q41290

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	November 16, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)