Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Major pollen allergen Pha a 1

Gene
N/A
Organism
Phalaris aquatica (Canary grass)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Pha a 1
Alternative name(s):
Allergen Pha a I
Allergen: Pha a 1
OrganismiPhalaris aquatica (Canary grass)
Taxonomic identifieri28479 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaePoodaePoeaePoeae Chloroplast Group 1 (Aveneae type)PhalaridinaePhalaris

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.1 Publication

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3486. Pha a 1.0101.
547. Pha a 1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 29291 PublicationAdd
BLAST
Chaini30 – 269240Major pollen allergen Pha a 1PRO_0000008718Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi38 – 381N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ41260.
SMRiQ41260. Positions 32-264.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini67 – 173107Expansin-like EG45PROSITE-ProRule annotationAdd
BLAST
Domaini187 – 26882Expansin-like CBDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the expansin family. Expansin B subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation
Contains 1 expansin-like EG45 domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR005795. LolPI.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01225. EXPANSNFAMLY.
PR00829. LOLP1ALLERGN.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q41260-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKMVCSSSS SSLLVVAALL AVFVGSAQGI AKVPPGPNIT AEYGDKWLDA
60 70 80 90 100
KSTWYGKPTG AGPKDNGGAC GYKDVDKAPF NGMTGCGNTP IFKDGRGCGS
110 120 130 140 150
CFELKCSKPE SCSGEPITVH ITDDNEEPIA PYHFDLSGHA FGSMAKKGEE
160 170 180 190 200
ENVRGAGELE LQFRRVKCKY PDGTKPTFHV EKGSNPNYLA LLVKYVDGDG
210 220 230 240 250
DVVAVDIKEK GKDKWIELKE SWGAIWRIDT PDKLTGPFTV RYTTEGGTKA
260
EFEDVIPEGW KADTHDASK
Length:269
Mass (Da):29,011
Last modified:November 1, 1997 - v1
Checksum:i05883A458ACE877F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti37 – 371P → G AA sequence (PubMed:7687099).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S80654 mRNA. Translation: AAB35984.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S80654 mRNA. Translation: AAB35984.1.

3D structure databases

ProteinModelPortaliQ41260.
SMRiQ41260. Positions 32-264.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3486. Pha a 1.0101.
547. Pha a 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR005795. LolPI.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01225. EXPANSNFAMLY.
PR00829. LOLP1ALLERGN.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMPAP1_PHAAQ
AccessioniPrimary (citable) accession number: Q41260
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 17, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.