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Q41247

- AL7A1_BRANA

UniProt

Q41247 - AL7A1_BRANA

Protein

Aldehyde dehydrogenase family 7 member A1

Gene

BTG-26

Organism
Brassica napus (Rape)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei168 – 1681Transition state stabilizerBy similarity
    Active sitei269 – 2691Proton acceptorPROSITE-ProRule annotation
    Active sitei303 – 3031NucleophilePROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi247 – 2526NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Stress response

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
    Alternative name(s):
    Antiquitin-1
    Brassica turgor-responsive/drought-induced gene 26 protein
    Short name:
    Btg-26
    Gene namesi
    Name:BTG-26
    OrganismiBrassica napus (Rape)Imported
    Taxonomic identifieri3708 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 494493Aldehyde dehydrogenase family 7 member A1PRO_0000056496Add
    BLAST

    Proteomic databases

    PRIDEiQ41247.

    Expressioni

    Inductioni

    By water stress, low temperature, heat shock, high salt and abscisic acid.1 Publication

    Interactioni

    Subunit structurei

    Homotetramer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ41247.
    SMRiQ41247. Positions 7-493.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q41247-1 [UniParc]FASTAAdd to Basket

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    MGSASKEYEF LSEIGLSSSH NLGNYVGGKW LGNGPLVSTL NPANNQVLPI    50
    AQVVEASLED YEIGLKACEE AAKTWMQVPA PKRGDIVRQI GDALRSKLDY 100
    LGRLLSLEMG KILAEGIGEV QEVIDMCDFA VGLSRQLNGS VIPSERPNHM 150
    MLEMWNPLGI VGVITAFNFP CAVLGWNACI ALVCGNCVVW KGAPTTPLIT 200
    IAMTKLVAEV LEKNHLPGAI FTAMCGGAEI GEAIAKDTRI PLVSFTGSSK 250
    VGLTVQQTVS ARSGKTLLEL SGNNAIIVMD DADIQLAARS VLFAAVGTAG 300
    QRCTTCRRLL LHESVYDKVL EQLLTSYKQV KIGDPLEKGT LLGPLHTPES 350
    KKNFEKGIEV IKSQGGKVLT GGKAVEGEGN FVEPTIIEIS SDAAVVKEEL 400
    FAPVLYALKF KTFEEAVAIN NSVPQGLSSS IFTRSPDNIF KWIGPMGSDC 450
    GIVNVNIPTN GAEIGGAFGG EKATGGGREA GSDSWKQYMR RSTW 494
    Length:494
    Mass (Da):52,688
    Last modified:January 23, 2007 - v3
    Checksum:i13ED0096563BAE13
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S77096 Genomic DNA. Translation: AAB33843.1.
    PIRiS53503.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    S77096 Genomic DNA. Translation: AAB33843.1 .
    PIRi S53503.

    3D structure databases

    ProteinModelPortali Q41247.
    SMRi Q41247. Positions 7-493.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q41247.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning and expression of a turgor-responsive gene in Brassica napus."
      Stroeher V.L., Boothe J.G., Good A.G.
      Plant Mol. Biol. 27:541-551(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION.
      Strain: cv. Bridger.
      Tissue: Leaf.
    2. "First purification of the antiquitin protein and demonstration of its enzymatic activity."
      Tang W.-K., Cheng C.H.K., Fong W.-P.
      FEBS Lett. 516:183-186(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-16.

    Entry informationi

    Entry nameiAL7A1_BRANA
    AccessioniPrimary (citable) accession number: Q41247
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 15, 2002
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 77 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3