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Protein

Aldehyde dehydrogenase family 7 member A1

Gene

BTG-26

Organism
Brassica napus (Rape)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei168 – 1681Transition state stabilizerBy similarity
Active sitei269 – 2691Proton acceptorPROSITE-ProRule annotation
Active sitei303 – 3031NucleophilePROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi247 – 2526NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Stress response

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
Alternative name(s):
Antiquitin-1
Brassica turgor-responsive/drought-induced gene 26 protein
Short name:
Btg-26
Gene namesi
Name:BTG-26
OrganismiBrassica napus (Rape)Imported
Taxonomic identifieri3708 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 494493Aldehyde dehydrogenase family 7 member A1PRO_0000056496Add
BLAST

Proteomic databases

PRIDEiQ41247.

Expressioni

Inductioni

By water stress, low temperature, heat shock, high salt and abscisic acid.1 Publication

Interactioni

Subunit structurei

Homotetramer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ41247.
SMRiQ41247. Positions 7-493.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q41247-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSASKEYEF LSEIGLSSSH NLGNYVGGKW LGNGPLVSTL NPANNQVLPI
60 70 80 90 100
AQVVEASLED YEIGLKACEE AAKTWMQVPA PKRGDIVRQI GDALRSKLDY
110 120 130 140 150
LGRLLSLEMG KILAEGIGEV QEVIDMCDFA VGLSRQLNGS VIPSERPNHM
160 170 180 190 200
MLEMWNPLGI VGVITAFNFP CAVLGWNACI ALVCGNCVVW KGAPTTPLIT
210 220 230 240 250
IAMTKLVAEV LEKNHLPGAI FTAMCGGAEI GEAIAKDTRI PLVSFTGSSK
260 270 280 290 300
VGLTVQQTVS ARSGKTLLEL SGNNAIIVMD DADIQLAARS VLFAAVGTAG
310 320 330 340 350
QRCTTCRRLL LHESVYDKVL EQLLTSYKQV KIGDPLEKGT LLGPLHTPES
360 370 380 390 400
KKNFEKGIEV IKSQGGKVLT GGKAVEGEGN FVEPTIIEIS SDAAVVKEEL
410 420 430 440 450
FAPVLYALKF KTFEEAVAIN NSVPQGLSSS IFTRSPDNIF KWIGPMGSDC
460 470 480 490
GIVNVNIPTN GAEIGGAFGG EKATGGGREA GSDSWKQYMR RSTW
Length:494
Mass (Da):52,688
Last modified:January 23, 2007 - v3
Checksum:i13ED0096563BAE13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S77096 Genomic DNA. Translation: AAB33843.1.
PIRiS53503.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S77096 Genomic DNA. Translation: AAB33843.1.
PIRiS53503.

3D structure databases

ProteinModelPortaliQ41247.
SMRiQ41247. Positions 7-493.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ41247.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning and expression of a turgor-responsive gene in Brassica napus."
    Stroeher V.L., Boothe J.G., Good A.G.
    Plant Mol. Biol. 27:541-551(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION.
    Strain: cv. Bridger.
    Tissue: Leaf.
  2. "First purification of the antiquitin protein and demonstration of its enzymatic activity."
    Tang W.-K., Cheng C.H.K., Fong W.-P.
    FEBS Lett. 516:183-186(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-16.

Entry informationi

Entry nameiAL7A1_BRANA
AccessioniPrimary (citable) accession number: Q41247
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 23, 2007
Last modified: January 7, 2015
This is version 78 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.