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Q41247 (AL7A1_BRANA) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aldehyde dehydrogenase family 7 member A1

EC=1.2.1.3
Alternative name(s):
Antiquitin-1
Brassica turgor-responsive/drought-induced gene 26 protein
Short name=Btg-26
Gene names
Name:BTG-26
OrganismBrassica napus (Rape)
Taxonomic identifier3708 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Protein attributes

Sequence length494 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Subunit structure

Homotetramer By similarity. UniProtKB P83402

Induction

By water stress, low temperature, heat shock, high salt and abscisic acid. Ref.1

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   Biological processStress response
   LigandNAD
   Molecular functionOxidoreductase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.2
Chain2 – 494493Aldehyde dehydrogenase family 7 member A1
PRO_0000056496

Regions

Nucleotide binding247 – 2526NAD By similarity UniProtKB Q56694

Sites

Active site2691Proton acceptor By similarity UniProtKB Q56694
Active site3031Nucleophile By similarity UniProtKB Q56694
Site1681Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q41247 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 13ED0096563BAE13

FASTA49452,688
        10         20         30         40         50         60 
MGSASKEYEF LSEIGLSSSH NLGNYVGGKW LGNGPLVSTL NPANNQVLPI AQVVEASLED 

        70         80         90        100        110        120 
YEIGLKACEE AAKTWMQVPA PKRGDIVRQI GDALRSKLDY LGRLLSLEMG KILAEGIGEV 

       130        140        150        160        170        180 
QEVIDMCDFA VGLSRQLNGS VIPSERPNHM MLEMWNPLGI VGVITAFNFP CAVLGWNACI 

       190        200        210        220        230        240 
ALVCGNCVVW KGAPTTPLIT IAMTKLVAEV LEKNHLPGAI FTAMCGGAEI GEAIAKDTRI 

       250        260        270        280        290        300 
PLVSFTGSSK VGLTVQQTVS ARSGKTLLEL SGNNAIIVMD DADIQLAARS VLFAAVGTAG 

       310        320        330        340        350        360 
QRCTTCRRLL LHESVYDKVL EQLLTSYKQV KIGDPLEKGT LLGPLHTPES KKNFEKGIEV 

       370        380        390        400        410        420 
IKSQGGKVLT GGKAVEGEGN FVEPTIIEIS SDAAVVKEEL FAPVLYALKF KTFEEAVAIN 

       430        440        450        460        470        480 
NSVPQGLSSS IFTRSPDNIF KWIGPMGSDC GIVNVNIPTN GAEIGGAFGG EKATGGGREA 

       490 
GSDSWKQYMR RSTW 

« Hide

References

[1]"Molecular cloning and expression of a turgor-responsive gene in Brassica napus."
Stroeher V.L., Boothe J.G., Good A.G.
Plant Mol. Biol. 27:541-551(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION.
Strain: cv. Bridger.
Tissue: Leaf.
[2]"First purification of the antiquitin protein and demonstration of its enzymatic activity."
Tang W.-K., Cheng C.H.K., Fong W.-P.
FEBS Lett. 516:183-186(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-16.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S77096 Genomic DNA. Translation: AAB33843.1.
PIRS53503.

3D structure databases

ProteinModelPortalQ41247.
SMRQ41247. Positions 7-493.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ41247.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAL7A1_BRANA
AccessionPrimary (citable) accession number: Q41247
Entry history
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 23, 2007
Last modified: March 19, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families