ID   PFPB_RICCO              Reviewed;         552 AA.
AC   Q41141;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 51.
DE   RecName: Full=Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta;
DE            Short=PFP;
DE            EC=2.7.1.90;
DE   AltName: Full=6-phosphofructokinase, pyrophosphate dependent;
DE   AltName: Full=Pyrophosphate-dependent 6-phosphofructose-1-kinase;
DE   AltName: Full=PPi-PFK;
GN   Name=PFP-BETA;
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids I; Malpighiales; Euphorbiaceae; Acalyphoideae;
OC   Acalypheae; Ricinus.
OX   NCBI_TaxID=3988;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   MEDLINE=95137384; PubMed=7835697; DOI=10.1016/0378-1119(94)00646-A;
RA   Todd J.F., Blakeley S.D., Dennis D.T.;
RT   "Structure of the genes encoding the alpha- and beta-subunits of
RT   castor pyrophosphate-dependent phosphofructokinase.";
RL   Gene 152:181-186(1995).
CC   -!- CATALYTIC ACTIVITY: Diphosphate + D-fructose 6-phosphate =
CC       phosphate + D-fructose 1,6-bisphosphate.
CC   -!- ENZYME REGULATION: Fru-2,6-P is an activator of the plant enzyme.
CC   -!- SUBUNIT: Tetramer of two alpha and two beta chains (By
CC       similarity).
CC   -!- MISCELLANEOUS: The active site might be on the beta subunit.
CC   -!- SIMILARITY: Belongs to the pyrophosphate-dependent
CC       phosphofructokinase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; Z32850; CAA83683.1; -; Genomic_DNA.
DR   PIR; T10107; T10107.
DR   HSSP; P70826; 1KZH.
DR   BRENDA; 2.7.1.90; 816.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047334; F:diphosphate-fructose-6-phosphate 1-phosphot...; IEA:EC.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR011183; PfpB_PPi_PFK.
DR   InterPro; IPR000023; Phosphofructokinase.
DR   Pfam; PF00365; PFK; 1.
DR   PIRSF; PIRSF005677; PPi_PFK_PfpB; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   ProDom; PD000707; Ppfruckinase; 1.
DR   TIGRFAMs; TIGR02477; PFKA_PPi; 1.
PE   3: Inferred from homology;
KW   Allosteric enzyme; ATP-binding; Glycolysis; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN         1    552       Pyrophosphate--fructose 6-phosphate 1-
FT                                phosphotransferase subunit beta.
FT                                /FTId=PRO_0000112049.
FT   ACT_SITE    214    214       Proton acceptor (By similarity).
SQ   SEQUENCE   552 AA;  60114 MW;  E4DC19ADB6317A8E CRC64;
     MATPNSGRAA SVYSEVQSSR IEHVLPLPSV LNHPFKIVQG PPSSAAGNPD EIAKLFPNLF
     GQPSAMLVPD VADSLDSNQQ LKIGLVLSGG QAPGGHNVIS GIFDYLQDRA KGSILYGFRG
     GPAGIMKCNY VQLTADYIHP YRNQGGFDMI CSGRDKIETP EQFKQAEETA GKLDLNGLVV
     IGGDDSNTNA CLLAENFRSK NLKTRVIGCP KTIDGDLKCK EVPTSFGFDT ACKIYSEMIG
     NVMIDARSTG KYYHFVRLMG RAASHITLEC ALQTHPNITI IGEEVAAKKL ALKDVTDYIV
     DVICKRADLG YNYGVILIPE GLIDFIPEVQ NLIAELNEIL AHDVVDEGGL WKKKLTSQSL
     QLFEFLPVAI QEQLMLERDP HGNVQVAKIE TEKMLIQMVE TELEKRKQQG TYKAHFKGQS
     HFFGYEGRCG LPTNFDSTYC YALGYAAGAL LHSGKTGLIS SVGNLGAPVA EWTVGGTALT
     SLMDVERRHG KFKPVIKKAM VELEGAPFKK FASLREEWAL KNRYVSPGPI QFMGPGSDAA
     SHTLLLELGS VA
//