ID   INO1_PHAVU              Reviewed;         511 AA.
AC   Q41107;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 50.
DE   RecName: Full=Inositol-3-phosphate synthase;
DE            EC=5.5.1.4;
DE   AltName: Full=Myo-inositol-1-phosphate synthase;
DE            Short=MI-1-P synthase;
DE            Short=IPS;
OS   Phaseolus vulgaris (Kidney bean) (French bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   rosids; eurosids I; Fabales; Fabaceae; Papilionoideae; Phaseoleae;
OC   Phaseolus.
OX   NCBI_TaxID=3885;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Taylor's horticultural; TISSUE=Root;
RA   Wang X., Johnson M.D.;
RT   "An isoform of 1L-myo-Inositol 1-phosphate synthase (EC 5.5.1.4) from
RT   Phaseolus vulgaris.";
RL   (er) Plant Gene Register PGR95-121.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = 1D-myo-inositol 3-
CC       phosphate.
CC   -!- COFACTOR: NAD (By similarity).
CC   -!- PATHWAY: Polyol metabolism; myo-inositol biosynthesis; myo-
CC       inositol from D-glucose 6-phosphate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the myo-inositol-1-phosphate synthase
CC       family.
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DR   EMBL; U38920; AAA91164.1; -; mRNA.
DR   PIR; T10964; T10964.
DR   HSSP; P11986; 1P1J.
DR   BRENDA; 5.5.1.4; 8.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004512; F:inositol-3-phosphate synthase activity; IEA:EC.
DR   GO; GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR002587; Myo-inos-1-P_Synthase.
DR   InterPro; IPR013021; Myo-inos-1-P_Synthase_GAPDH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11510; Inos-1-P_synth; 1.
DR   Pfam; PF01658; Inos-1-P_synth; 1.
DR   Pfam; PF07994; NAD_binding_5; 1.
DR   PIRSF; PIRSF015578; Myoinos-ppht_syn; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Inositol biosynthesis; Isomerase; NAD;
KW   Phospholipid biosynthesis.
FT   CHAIN         1    511       Inositol-3-phosphate synthase.
FT                                /FTId=PRO_0000195196.
SQ   SEQUENCE   511 AA;  56527 MW;  76A9558088CA58EF CRC64;
     MFIESFKVES PNVKYTENEI HSVYDYETTE VVHEKTVNGT YQWIVKPKTV KYDFKTDIRV
     PKLGVMLVGL GGNNGSTLTA GVIANKEGIS WATKDKVQQA NYFGSLTQAS SIRVGSFNGE
     EIYAPFKSLL PMVNPDDVVF GGWDISDMNL ADAMARARVL DIDLQKQLRP YMENIVPLPG
     IFDPDFIAAN QGSRANHVIK GTKKEQVDHI IKDMREFKEK NKVDKVVVLW TANTERYSNE
     VVGMNDTMED LMESVDRDEA EISPSTLYAI ACVLEGIPFI NGSPQHTFVP GLIDMAIRNN
     VLIGGDDFKS GQTKMKSVLG DFLVGAGIKP TSIVSYNHLG NNDGMNLSAP QTFRSKEISK
     SNVVDDMVAS NGILFEPGEH PDHVVVIKYV PYVADSKRAM DEYTSEIFMG GKNTIVMHNT
     CEDSLLAAPI ILDLVLLAEL STRIQFKSEG EGKFHSFHPV ATILSYLTKA PLVPPGTPVI
     NALSKQRAML ENIMRACVGL APENNMIMEF K
//