Q40962 (MPA5A_PHLPR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Pollen allergen Phl p 5a Alternative name(s): Allergen Phl p Va Allergen=Phl p 5a
Organism	Phleum pratense (Common timothy)
Taxonomic identifier	15957 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Pooideae › Poeae › Alopecurinae › Phleum

Protein attributes

Sequence length	286 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted Potential.
Allergenic properties	Causes an allergic reaction in human. Causes grass pollen allergy.
Sequence similarities	Belongs to the Poa p IX/Phl p VI allergen family.

Ontologies

Keywords
Cellular component	Secreted
Disease	Allergen
Gene Ontology (GO)
Biological_process	type I hypersensitivity Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 286	›286	Pollen allergen Phl p 5a		PRO_0000096551
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	Q40962 [UniParc]. Last modified July 15, 1998. Version 2. Checksum: C0E12BE83A3070F5	FASTA	286	28,530
	10 20 30 40 50 60 ADLGYGPATP AAPAAGYTPA TPAAPAGADA AGKATTEEQK LIEKINAGFK AALAGAGVQP 70 80 90 100 110 120 ADKYRTFVAT FGPASNKAFA EGLSGEPKGA AESSSKAALT SKLDAAYKLA YKTAEGATPE 130 140 150 160 170 180 AKYDAYVATL SEALRIIAGT LEVHAVKPAA EEVKVIPAGE LQVIEKVDAA FKVAATAANA 190 200 210 220 230 240 APANDKFTVF EAAFNDEIKA STGGAYESYK FIPALEAAVK QAYAATVATA PEVKYTVFET 250 260 270 280 ALKKAITAMS EAQKAAKPAA AATATATAAV GAATGAATAA TGGYKV

References

[1]	"Major allergen Phl p Va (timothy grass) bears at least two different IgE-reactive epitopes." Bufe A., Becker W.M., Schramm G., Petersen A., Mamat U., Schlaak M. J. Allergy Clin. Immunol. 94:173-181(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: Agrostideae.
[2]	Bufe A. Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X70942 mRNA. Translation: CAA50281.1.
3D structure databases
ProteinModelPortal	Q40962.
SMR	Q40962. Positions 34-146, 156-257.
ModBase	Search...
Protein family/group databases
Allergome	558. Phl p 5. 560. Phl p 5.0102.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	Q40962.
Family and domain databases
Gene3D	1.20.120.320. 2 hits.
InterPro	IPR001778. POA_allergen. IPR002914. POA_allergen_N. [Graphical view]
Pfam	PF01620. Pollen_allerg_2. 2 hits. [Graphical view]
PRINTS	PR00833. POAALLERGEN.
SUPFAM	SSF81736. POA_allergen_N. 2 hits.
ProtoNet	Search...

Entry information

Entry name

MPA5A_PHLPR

Accession

Primary (citable) accession number: Q40962

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	July 15, 1998
Last modified:	April 3, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program