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Protein

Probable non-specific lipid-transfer protein 1

Gene
N/A
Organism
Parietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandLipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable non-specific lipid-transfer protein 1
Short name:
LTP
Alternative name(s):
Allergen Par j I
Major pollen allergen Par j 1.0201
Protein P1
Allergen: Par j 1.0201
OrganismiParietaria judaica (Pellitory-of-the-wall) (Parietaria diffusa)
Taxonomic identifieri33127 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesUrticaceaeParietaria

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Binds to IgE and induces histamine release from basophils of Pj-pollen-allergic subjects.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei503. Par j 1.
506. Par j 1.0201.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 36Sequence analysisAdd BLAST36
ChainiPRO_000001839737 – 138Probable non-specific lipid-transfer protein 1Add BLAST102

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi40 ↔ 88By similarity
Disulfide bondi50 ↔ 65By similarity
Disulfide bondi66 ↔ 111By similarity
Disulfide bondi86 ↔ 127By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliQ40905.
SMRiQ40905.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the plant LTP family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
PfamiView protein in Pfam
PF00234. Tryp_alpha_amyl. 1 hit.
PRINTSiPR00382. LIPIDTRNSFER.
SMARTiView protein in SMART
SM00499. AAI. 1 hit.
SUPFAMiSSF47699. SSF47699. 1 hit.
PROSITEiView protein in PROSITE
PS00597. PLANT_LTP. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q40905-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTVSARSSV ALVVIVAAVL VWTSSASVAP APAPGSEETC GTVVGALMPC
60 70 80 90 100
LPFVQGKEKE PSKGCCSGAK RLDGETKTGP QRVHACECIQ TAMKTYSDID
110 120 130
GKLVSEVPKH CGIVDSKLPP IDVNMDCKTL GVLHYKGN
Length:138
Mass (Da):14,414
Last modified:November 1, 1996 - v1
Checksum:iA4E66230FEC0B6EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X85012 mRNA. Translation: CAA59370.1.
PIRiS52933.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiNLT13_PARJU
AccessioniPrimary (citable) accession number: Q40905
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 15, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families