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Protein
Submitted name:

Polyphenol oxidase

Gene
N/A
Organism
Phytolacca americana (American pokeweed) (Phytolacca decandra)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Cu2+UniRule annotationNote: Binds 2 copper ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi180 – 1801Copper AUniRule annotation
Metal bindingi201 – 2011Copper AUniRule annotation
Metal bindingi210 – 2101Copper AUniRule annotation
Metal bindingi334 – 3341Copper BUniRule annotation
Metal bindingi338 – 3381Copper BUniRule annotation
Metal bindingi368 – 3681Copper BUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Polyphenol oxidaseImported
OrganismiPhytolacca americana (American pokeweed) (Phytolacca decandra)Imported
Taxonomic identifieri3527 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesPhytolaccaceaePhytolacca

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi118 ↔ 181UniRule annotation
Cross-linki184 ↔ 2012'-(S-cysteinyl)-histidine (Cys-His)UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ40774.
SMRiQ40774. Positions 97-431.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini201 – 21818Tyrosinase_Cu-bdInterPro annotationAdd
BLAST

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR016213. Polyphenol_oxidase.
IPR022740. Polyphenol_oxidase_C.
IPR022739. Polyphenol_oxidase_cen.
IPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF12142. PPO1_DWL. 1 hit.
PF12143. PPO1_KFDV. 1 hit.
PF00264. Tyrosinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000290. PPO_plant. 1 hit.
PRINTSiPR00092. TYROSINASE.
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS00497. TYROSINASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q40774-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLSSPPTS TTTSATTLAT NISNPLFPKT SQFSLPGCRN RRHVMPKISC
60 70 80 90 100
KVDKDELYPK TTNDDGNTNK LDRRNMLIGL GSIYGAGTTL GGGPATLAAP
110 120 130 140 150
LITPNPTEFG ASDVGLNCCP PTARNIVDFQ LPPQPTTLRV RPPAHLVDDQ
160 170 180 190 200
YLQKFSRAIS LMKALPANDP RNFSQQANVH CAYCDGGYTQ TGFPNLELQV
210 220 230 240 250
HFSWLFFPFH RFYLYFFERI LGKLINDPSF AIPFWNWDTP AGMQIPGIYT
260 270 280 290 300
SPNSPLYDPR RDRAHQPPRV IDLNYDGQDD PNDLTGQDLI SANLTLMYRQ
310 320 330 340 350
MVSNSTTTRL FLGQPFRVGN RPSPGAGSIE NVPHGPVHVW TGDPNQPNGE
360 370 380 390 400
DMGTFYSAAR VPIFYAHHAI VDRMWAIWNA LGNDRQDFTD SDWLNASCIV
410 420 430 440 450
YGGNGQAVRV PSRDSLDKAR LGYTYQGVDL PEWPSSPTPQ RSKLNTTSRI
460 470 480 490 500
PMSPTLSTVK FPRALDSVIR TDVKRSKKSR GRREKEVEEE ILVIEIELEK
510 520 530 540 550
DIYVKFDVHV NDEDEVPFKK TRVLTEFAGS FVNVPHKHHK EGQHGMKTAL
560 570 580
RLGLTALIEE LGADDDETVT ITLVPRAGND VVVTRM
Length:586
Mass (Da):65,311
Last modified:November 1, 1996 - v1
Checksum:i6FB1ADDE7231F894
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45385 mRNA. Translation: BAA08234.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D45385 mRNA. Translation: BAA08234.1.

3D structure databases

ProteinModelPortaliQ40774.
SMRiQ40774. Positions 97-431.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR016213. Polyphenol_oxidase.
IPR022740. Polyphenol_oxidase_C.
IPR022739. Polyphenol_oxidase_cen.
IPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF12142. PPO1_DWL. 1 hit.
PF12143. PPO1_KFDV. 1 hit.
PF00264. Tyrosinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000290. PPO_plant. 1 hit.
PRINTSiPR00092. TYROSINASE.
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS00497. TYROSINASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ40774_PHYAM
AccessioniPrimary (citable) accession number: Q40774
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 13, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.