ID   MADS3_ORYSJ             Reviewed;         236 AA.
AC   Q40704; Q6Q7W1;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 50.
DE   RecName: Full=MADS-box transcription factor 3;
DE   AltName: Full=OsMADS3;
DE   AltName: Full=Protein AGAMOUS-like;
DE   AltName: Full=RMADS222;
GN   Name=MADS3; Synonyms=RAG;
GN   OrderedLocusNames=Os01g0201700, LOC_Os01g10504;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Ehrhartoideae; Oryzeae; Oryza.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC   TISSUE=Flower;
RX   MEDLINE=96017609; PubMed=7579155; DOI=10.1007/BF00019114;
RA   Kang H.-G., Noh Y.-S., Chung Y.-Y., Costa M.A., An K., An G.;
RT   "Phenotypic alterations of petal and sepal by ectopic expression of a
RT   rice MADS box gene in tobacco.";
RL   Plant Mol. Biol. 29:1-10(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RA   Yao Q., Peng R., Xiong A.;
RT   "Molecular and phylogenetic analyses of the complete MADS-box
RT   transcription factor family in rice.";
RL   Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   MEDLINE=22337376; PubMed=12447438; DOI=10.1038/nature01184;
RA   Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA   Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA   Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M.,
RA   Okamoto M., Ando T., Aoki H., Arita K., Hamada M., Harada C.,
RA   Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M.,
RA   Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K.,
RA   Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I.,
RA   Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y.,
RA   Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M.,
RA   Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M.,
RA   Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K.,
RA   Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K.,
RA   Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y.,
RA   Yano M., Jiang J., Gojobori T.;
RT   "The genome sequence and structure of rice chromosome 1.";
RL   Nature 420:312-316(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC   STRAIN=cv. Nipponbare;
RX   MEDLINE=22752273; PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [5]
RP   FUNCTION.
RX   PubMed=9869408; DOI=10.1023/A:1006051911291;
RA   Kang H.-G., Jeon J.-S., Lee S., An G.;
RT   "Identification of class B and class C floral organ identity genes
RT   from rice plants.";
RL   Plant Mol. Biol. 38:1021-1029(1998).
RN   [6]
RP   TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX   PubMed=10945340;
RA   Kyozuka J., Kobayashi T., Morita M., Shimamoto K.;
RT   "Spatially and temporally regulated expression of rice MADS box genes
RT   with similarity to Arabidopsis class A, B and C genes.";
RL   Plant Cell Physiol. 41:710-718(2000).
RN   [7]
RP   FUNCTION.
RX   PubMed=11828031; DOI=10.1093/pcp/pcf010;
RA   Kyozuka J., Shimamoto K.;
RT   "Ectopic expression of OsMADS3, a rice ortholog of AGAMOUS, caused a
RT   homeotic transformation of lodicules to stamens in transgenic rice
RT   plants.";
RL   Plant Cell Physiol. 43:130-135(2002).
RN   [8]
RP   FUNCTION, DISRUPTION PHENOTYPE, AND DEVELOPMENTAL STAGE.
RX   PubMed=16326928; DOI=10.1105/tpc.105.037200;
RA   Yamaguchi T., Lee D.-Y., Miyao A., Hirochika H., An G., Hirano H.;
RT   "Functional diversification of the two C-class MADS box genes OSMADS3
RT   and OSMADS58 in Oryza sativa.";
RL   Plant Cell 18:15-28(2006).
CC   -!- FUNCTION: Probable transcription factor involved in the
CC       development of floral organs. Acts as C-class protein in
CC       association with MADS58. Involved in the control of lodicule
CC       number (whorl 2), stamen specification (whorl 3) and floral
CC       meristem determinacy (whorl 4), but not in the regulation of
CC       carpel morphogenesis. Plays a more predominant role in controlling
CC       lodicule development and in specifying stamen identity than
CC       MADS58.
CC   -!- SUBCELLULAR LOCATION: Nucleus (Probable).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q40704-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q40704-2; Sequence=VSP_017779;
CC         Note=No experimental confirmation available;
CC       Name=3;
CC         IsoId=Q40704-3; Sequence=VSP_017777, VSP_017778;
CC         Note=No experimental confirmation available;
CC   -!- TISSUE SPECIFICITY: Expressed in lemmas, paleas and lodicules.
CC   -!- DEVELOPMENTAL STAGE: Expressed at early stage of flower
CC       development in stamen anlagen before stamen initiation, and at
CC       later stage in lodicule and ovule primordia initiation region.
CC   -!- DISRUPTION PHENOTYPE: Homeotic transformation of stamens into
CC       lodicules, and ectopic development of lodicules where they do not
CC       form in the wild-type.
CC   -!- MISCELLANEOUS: The transformation of lodicules into stamens is
CC       observed in overexpressing plants.
CC   -!- SIMILARITY: Contains 1 K-box domain.
CC   -!- SIMILARITY: Contains 1 MADS-box domain.
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DR   EMBL; L37528; AAA99964.1; -; mRNA.
DR   EMBL; AY553724; AAS60204.1; -; mRNA.
DR   EMBL; AP003105; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK108568; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; S59480; S59480.
DR   HSSP; Q02078; 1EGW.
DR   IntAct; Q40704; 3.
DR   Gramene; Q40704; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
DR   GO; GO:0006350; P:transcription; IEA:UniProtKB-KW.
DR   InterPro; IPR002487; TF_Kbox.
DR   InterPro; IPR002100; TF_MADSbox.
DR   Pfam; PF01486; K-box; 1.
DR   Pfam; PF00319; SRF-TF; 1.
DR   PRINTS; PR00404; MADSDOMAIN.
DR   SMART; SM00432; MADS; 1.
DR   PROSITE; PS51297; K_BOX; 1.
DR   PROSITE; PS00350; MADS_BOX_1; 1.
DR   PROSITE; PS50066; MADS_BOX_2; 1.
PE   2: Evidence at transcript level;
KW   Activator; Alternative splicing; Developmental protein;
KW   Differentiation; DNA-binding; Flowering; Nucleus; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    236       MADS-box transcription factor 3.
FT                                /FTId=PRO_0000229893.
FT   DOMAIN        1     61       MADS-box.
FT   DOMAIN       87    178       K-box.
FT   VAR_SEQ     110    114       RTIVG -> LTRLA (in isoform 3).
FT                                /FTId=VSP_017777.
FT   VAR_SEQ     115    236       Missing (in isoform 3).
FT                                /FTId=VSP_017778.
FT   VAR_SEQ     231    236       QQPAFN -> SRPSISFGVDTVRTHVR (in isoform
FT                                2).
FT                                /FTId=VSP_017779.
SQ   SEQUENCE   236 AA;  27141 MW;  241BD9BCE2DAD35F CRC64;
     MGRGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRLYEYANN
     SVKSTVERYK KANSDTSNSG TVAEVNAQHY QQESSKLRQQ ISSLQNANSR TIVGDSINTM
     SLRDLKQVEN RLEKGIAKIR ARKNELLYAE VEYMQKREVE LQNDNMYLRS KVVENERGQQ
     PLNMMGAAST SEYDHMVNNP YDSRNFLQVN IMQQPQHYAH QLQPTTLQLG QQPAFN
//