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Protein

MADS-box transcription factor 4

Gene

MADS4

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transcription factor involved in the development of floral organs. B-class protein required for normal development of lodicules and stamens (whorls 2 and 3). May function as a heterodimer with MADS16.1 Publication

Miscellaneous

Antisense inhibition of MADS4 expression transforms lodicules and stamens into palea/lemma-like and carpel-like organs, respectively.

GO - Molecular functioni

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • positive regulation of transcription by RNA polymerase II Source: InterPro
  • specification of floral organ identity Source: UniProtKB
  • specification of stamen identity Source: AgBase
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processDifferentiation, Flowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
MADS-box transcription factor 4
Alternative name(s):
OsMADS4
Gene namesi
Name:MADS4
Ordered Locus Names:Os05g0423400, LOC_Os05g34940
ORF Names:OJ1212_B02.5
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001995001 – 215MADS-box transcription factor 4Add BLAST215

Proteomic databases

PaxDbiQ40703

Expressioni

Tissue specificityi

Highly expressed in lodicules, at intermediate levels in stamens, and weakly in carpels. Expressed in pollen.3 Publications

Gene expression databases

ExpressionAtlasiQ40703 differential
GenevisibleiQ40703 OS

Interactioni

Subunit structurei

May interact with the K-box of MADS16.

GO - Molecular functioni

Protein-protein interaction databases

STRINGi39947.LOC_Os05g34940.1

Structurei

3D structure databases

ProteinModelPortaliQ40703
SMRiQ40703
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61MADS-boxPROSITE-ProRule annotationAdd BLAST61
Domaini89 – 175K-boxPROSITE-ProRule annotationAdd BLAST87

Phylogenomic databases

eggNOGiKOG0014 Eukaryota
COG5068 LUCA
HOGENOMiHOG000155301
InParanoidiQ40703
OMAiLAFRVHQ
OrthoDBiEOG09360M2K

Family and domain databases

CDDicd00265 MADS_MEF2_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033896 MADS_MEF2-like
IPR002487 TF_Kbox
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF01486 K-box, 1 hit
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS51297 K_BOX, 1 hit
PS50066 MADS_BOX_2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 2 (identifier: Q40703-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGRGKIEIKR IENSTNRQVT FSKRRAGILK KAREIGVLCD AEVGVVIFSS
60 70 80 90 100
AGKLSDYCTP KTTSVFPPLS RILEKYQTNS GKILWDEKHK SLSAEIDRVK
110 120 130 140 150
KENDNMQIEL RHMKGEDLNS LQPKELIAIE EALNNGQANL RDKMMDHWRM
160 170 180 190 200
HKRNEKMLED EHKMLAFRVH QQEVELSGGI RELELGYHHD DRDFAASMPF
210
TFRVQPSHPN LQQEK
Note: May be due to intron retention. No experimental confirmation available.
Length:215
Mass (Da):24,908
Last modified:August 30, 2005 - v3
Checksum:iFD24ED8F4ED1F213
GO
Isoform 1 (identifier: Q40703-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     64-68: Missing.

Show »
Length:210
Mass (Da):24,381
Checksum:iC3F940A6CC9ECCF4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti26A → S in AAC05723 (Ref. 1) Curated1
Sequence conflicti41A → R in AAC05723 (Ref. 1) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01539464 – 68Missing in isoform 1. 1 Publication5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L37527 mRNA Translation: AAC05723.1
AC109595 Genomic DNA Translation: AAV24770.1
AP008211 Genomic DNA Translation: BAF17504.1
AP014961 Genomic DNA Translation: BAS94096.1
AK100233 mRNA Translation: BAG94502.1
PIRiT03902
UniGeneiOs.2214

Genome annotation databases

EnsemblPlantsiOs05t0423400-01; Os05t0423400-01; Os05g0423400 [Q40703-1]
GrameneiOs05t0423400-01; Os05t0423400-01; Os05g0423400 [Q40703-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiMADS4_ORYSJ
AccessioniPrimary (citable) accession number: Q40703
Secondary accession number(s): Q0DI19, Q60EP4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: August 30, 2005
Last modified: May 23, 2018
This is version 115 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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