Q40687 (GBB_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Guanine nucleotide-binding protein subunit beta

Gene names

Ordered Locus Names:	Os03g0669200, LOC_Os03g46650
ORF Names:	OSJNBa0039O18.9

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subunit structure	G proteins are composed of 3 units, alpha, beta and gamma.
Sequence similarities	Belongs to the WD repeat G protein beta family. Contains 7 WD repeats.

Ontologies

Keywords
Domain	Repeat WD repeat
Molecular function	Transducer
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	G-protein coupled receptor signaling pathway Inferred from expression pattern Ref.1. Source: Gramene defense response to fungus, incompatible interaction Inferred from electronic annotation. Source: EnsemblPlants/Gramene endoplasmic reticulum unfolded protein response Inferred from electronic annotation. Source: EnsemblPlants/Gramene fruit development Inferred from electronic annotation. Source: EnsemblPlants/Gramene jasmonic acid mediated signaling pathway Inferred from electronic annotation. Source: EnsemblPlants/Gramene lateral root development Inferred from electronic annotation. Source: EnsemblPlants/Gramene organ morphogenesis Inferred from electronic annotation. Source: EnsemblPlants/Gramene response to ethylene stimulus Inferred from electronic annotation. Source: EnsemblPlants/Gramene seed germination Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Cellular_component	Cul4-RING ubiquitin ligase complex Inferred from electronic annotation. Source: EnsemblPlants/Gramene endoplasmic reticulum Inferred from electronic annotation. Source: EnsemblPlants/Gramene plasma membrane Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	signal transducer activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
GPA1	Q0DJ33	2	EBI-1100119,EBI-1100098
OSJNBa0026E05.11-1	Q6YXX9	4	EBI-1100119,EBI-1100089
RGG1	Q75WU1	4	EBI-1100119,EBI-1100093

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 380	380	Guanine nucleotide-binding protein subunit beta		PRO_0000127725
Regions
	Repeat	64 – 94	31	WD 1
	Repeat	106 – 136	31	WD 2
	Repeat	155 – 186	32	WD 3
	Repeat	203 – 234	32	WD 4
	Repeat	247 – 277	31	WD 5
	Repeat	296 – 326	31	WD 6
	Repeat	342 – 372	31	WD 7

Sequences

	Sequence		Length	Mass (Da)
	Q40687 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 36CE374E2A3E8EB0	FASTA	380	41,752
	10 20 30 40 50 60 MASVAELKEK HAAATASVNS LRERLRQRRQ MLLDTDVERY SRTQGRTPVS FNPTDLVCCR 70 80 90 100 110 120 TLQGHSGKVY SLDWTPEKNW IVSASQDGRL IVWNALTSQK THAIKLHCPW VMTCAFAPNG 130 140 150 160 170 180 QSVACGGLDS ACSIFNLNSQ ADRDGNIPVS RILTGHKGYV SSCQYVPDQE TRLITSSGDQ 190 200 210 220 230 240 TCVLWDVTTG QRISIFGGEF PSGHTADVLS LSINSSNSNM FVSGSCDATV RLWDIRIASR 250 260 270 280 290 300 AVRTYHGHEG DINSVKFFPD GQRFGTGSDD GTCRLFDVRT GHQLQVYSRE PDRNDNELPT 310 320 330 340 350 360 VTSIAFSISG RLLFAGYSNG DCYVWDTLLA EVVLNLGNLQ NSHEGRISCL GLSSDGSALC 370 380 TGSWDKNLKI WAFSGHRKIV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning and characterization of a cDNA for the beta subunit of a G protein from rice." Ishikawa A., Iwasaki Y., Asahi T. Plant Cell Physiol. 37:223-228(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X89737 Genomic DNA. Translation: CAA61889.1. AC133930 Genomic DNA. Translation: AAP44640.1.
PIR	T03765.
3D structure databases
ProteinModelPortal	Q40687.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q40687. 3 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g46650.1; LOC_Os03g46650.1; LOC_Os03g46650.
Organism-specific databases
Gramene	Q40687.
Phylogenomic databases
eggNOG	COG2319.
HOGENOM	HOG000176356.
OMA	CMLWDIE.
Gene expression databases
ArrayExpress	Q40687.
Family and domain databases
Gene3D	2.130.10.10. 1 hit.
InterPro	IPR020472. G-protein_beta_WD-40_rep. IPR001632. Gprotein_B. IPR016346. Guanine_nucleotide-bd_bsu. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. [Graphical view]
Pfam	PF00400. WD40. 7 hits. [Graphical view]
PIRSF	PIRSF002394. GN-bd_beta. 1 hit.
PRINTS	PR00319. GPROTEINB. PR00320. GPROTEINBRPT.
SMART	SM00320. WD40. 7 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. 3 hits. PS50082. WD_REPEATS_2. 5 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GBB_ORYSJ

Accession

Primary (citable) accession number: Q40687
Secondary accession number(s): Q7G5X0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program