UniProtKB - Q40677 (ALFP_ORYSJ)
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Protein
Fructose-bisphosphate aldolase, chloroplastic
Gene
ALDP
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Plays a key role in glycolysis and gluconeogenesis.By similarity
Catalytic activityi
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.By similarity
: glycolysis Pathwayi
This protein is involved in step 4 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.CuratedProteins known to be involved in the 4 steps of the subpathway in this organism are:
- no protein annotated in this organism
- Glucose-6-phosphate isomerase (Os06g0256500), Glucose-6-phosphate isomerase, Glucose-6-phosphate isomerase, Glucose-6-phosphate isomerase (Os08g0478800), Glucose-6-phosphate isomerase (OsJ_27683), Glucose-6-phosphate isomerase (Os06g0256500), Glucose-6-phosphate isomerase, cytosolic A (Os03g0776000), Glucose-6-phosphate isomerase, cytosolic B (Os06g0256500), Glucose-6-phosphate isomerase, Glucose-6-phosphate isomerase (Os09g0465600)
- ATP-dependent 6-phosphofructokinase (PFK), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (PFP-ALPHA), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (PFK), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (Os02g0714200), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (Os09g0298100), ATP-dependent 6-phosphofructokinase (Os09g0415800), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (PFK), ATP-dependent 6-phosphofructokinase (Os05g0524400), ATP-dependent 6-phosphofructokinase (Os10g0405600), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta (PFP-BETA), ATP-dependent 6-phosphofructokinase (PFK), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (P0652D10.35), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (P0410E11.122), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (PFPA4), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha (Os06g0326400), ATP-dependent 6-phosphofructokinase (PFK)
- Fructose-bisphosphate aldolase, chloroplastic (ALDP), Fructose-bisphosphate aldolase (OsJ_21934), Fructose-bisphosphate aldolase (OsJ_00159), Fructose-bisphosphate aldolase (Os08g0120600), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase (Os06g0608700), Fructose-bisphosphate aldolase 1, cytoplasmic (FBA1), Fructose-bisphosphate aldolase (LOC_Os11g07020), Fructose-bisphosphate aldolase 2, cytoplasmic (FBA2), Fructose-bisphosphate aldolase (Os01g0118000), Fructose-bisphosphate aldolase (LOC_Os12g07210), Fructose-bisphosphate aldolase 3, cytoplasmic (FBA3)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 72 | SubstrateBy similarity | 1 | |
Active sitei | 215 | Proton acceptorBy similarity | 1 | |
Active sitei | 257 | Schiff-base intermediate with dihydroxyacetone-PBy similarity | 1 | |
Binding sitei | 329 | SubstrateBy similarity | 1 | |
Sitei | 388 | Necessary for preference for fructose 1,6-bisphosphate over fructose 1-phosphateBy similarity | 1 |
GO - Molecular functioni
- fructose-bisphosphate aldolase activity Source: Gramene
GO - Biological processi
- gluconeogenesis Source: UniProtKB
- glycolytic process Source: UniProtKB
Keywordsi
Molecular function | Lyase |
Biological process | Glycolysis |
Ligand | Schiff base |
Enzyme and pathway databases
UniPathwayi | UPA00109; UER00183. |
Names & Taxonomyi
Protein namesi | Recommended name: Fructose-bisphosphate aldolase, chloroplasticCurated (EC:4.1.2.13Curated)Alternative name(s): Chloroplastic aldolase1 Publication Short name: AldP1 Publication |
Gene namesi | Name:ALDPCurated Ordered Locus Names:Os11g0171300Imported, LOC_Os11g07020Imported ORF Names:OsJ_33121Imported |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 38 | Chloroplast1 PublicationAdd BLAST | 38 | |
ChainiPRO_0000001112 | 39 – 388 | Fructose-bisphosphate aldolase, chloroplasticAdd BLAST | 350 |
Proteomic databases
PaxDbi | Q40677. |
PRIDEi | Q40677. |
Expressioni
Tissue specificityi
Expressed in leaf mesophyll cells.1 Publication
Inductioni
By exposure to light.1 Publication
Gene expression databases
ExpressionAtlasi | Q40677. baseline and differential. |
Genevisiblei | Q40677. OS. |
Interactioni
Subunit structurei
Homotetramer.By similarity
Protein-protein interaction databases
IntActi | Q40677. 1 interactor. |
STRINGi | 39947.LOC_Os11g07020.1. |
Structurei
3D structure databases
ProteinModelPortali | Q40677. |
SMRi | Q40677. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 299 – 301 | Substrate bindingBy similarity | 3 |
Sequence similaritiesi
Belongs to the class I fructose-bisphosphate aldolase family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG1557. Eukaryota. COG3588. LUCA. |
HOGENOMi | HOG000220876. |
InParanoidi | Q40677. |
KOi | K01623. |
OMAi | QGARFCK. |
OrthoDBi | EOG09360CPA. |
Family and domain databases
Gene3Di | 3.20.20.70. 1 hit. |
InterProi | View protein in InterPro IPR029768. Aldolase_I_AS. IPR013785. Aldolase_TIM. IPR000741. FBA_I. |
Pfami | View protein in Pfam PF00274. Glycolytic. 1 hit. |
PROSITEi | View protein in PROSITE PS00158. ALDOLASE_CLASS_I. 1 hit. |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q40677-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASATLLKSS FLPKKSEWGA TRQAAAPKPV TVSMVVRAGA YDDELVKTAK
60 70 80 90 100
TIASPGRGIL AMDESNATCG KRLASIGLEN TEANRQAYRT LLVTAPGLGQ
110 120 130 140 150
YISGAILFEE TLYQSTVDGK KIVDILTEQK IVPGIKVDKG LVPLAGSNNE
160 170 180 190 200
SWCQGLDGLA SREAAYYQQG ARFAKWRTVV SIPNGPSELA VKEAAWGLAR
210 220 230 240 250
YAAISQDNGL VPIVEPEILL DGEHGIDRTF EVAQKVWAET FFYMAENNVM
260 270 280 290 300
FEGILLKPSM VTPGAECKDR ATPEQVSDYT LKLLHRRIPP AVPGIMFLSG
310 320 330 340 350
GQSEVEATQN LNAMNQGPNP WHVSFSYARA LQNTCLKTWG GQPENVKAAQ
360 370 380
DALLLRAKAN SLAQLGKYTS DGEAAEAKEG MFVKNYVY
Sequence cautioni
The sequence AAX95073 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence ABA91631 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence ABA91632 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 156 | L → R in BAA02730 (PubMed:8163192).Curated | 1 | |
Sequence conflicti | 294 | G → A in BAA02730 (PubMed:8163192).Curated | 1 | |
Sequence conflicti | 352 | A → R in BAA02730 (PubMed:8163192).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D13513 Genomic DNA. Translation: BAA02730.1. JX972166 mRNA. Translation: AGT38460.1. AC128643 Genomic DNA. Translation: AAX95072.1. AC128643 Genomic DNA. Translation: AAX95073.1. Sequence problems. DP000010 Genomic DNA. Translation: ABA91630.2. DP000010 Genomic DNA. Translation: ABA91631.2. Sequence problems. DP000010 Genomic DNA. Translation: ABA91632.2. Sequence problems. AP008217 Genomic DNA. Translation: BAF27707.1. AP014967 Genomic DNA. Translation: BAT12868.1. CM000148 Genomic DNA. Translation: EAZ17583.1. AK104899 mRNA. Translation: BAG97016.1. |
PIRi | T03679. |
RefSeqi | XP_015616895.1. XM_015761409.1. |
UniGenei | Os.7988. |
Genome annotation databases
EnsemblPlantsi | Os11t0171300-01; Os11t0171300-01; Os11g0171300. |
GeneIDi | 4349897. |
Gramenei | Os11t0171300-01; Os11t0171300-01; Os11g0171300. |
KEGGi | osa:4349897. |
Similar proteinsi
Entry informationi
Entry namei | ALFP_ORYSJ | |
Accessioni | Q40677Primary (citable) accession number: Q40677 Secondary accession number(s): Q2R9Z9 U5KP25 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | October 25, 2005 | |
Last modified: | March 28, 2018 | |
This is version 116 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |