Q40322 (Q40322_MENSP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: 4S-limonene synthase EMBL AAC37366.1
Organism	Mentha spicata (Spearmint) EMBL AAC37366.1
Taxonomic identifier	29719 [NCBI]
Taxonomic lineage	Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Lamiales › Lamiaceae › Nepetoideae › Mentheae › Mentha

Protein attributes

Sequence length	599 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Transit peptide EMBL AAC37366.1
Ligand	Magnesium SAAS SAAS008930 Metal-binding SAAS SAAS008930
Technical term	3D-structure PDB 2ONG PDB 2ONH
Gene Ontology (GO)
Molecular function	lyase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 99	99	Potential EMBL AAC37366.1
	Chain	100 – 599	500	4S-limonene synthase EMBL AAC37366.1		PRO_5000142170

Sequences

	Sequence		Length	Mass (Da)
	Q40322 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 8BF53D23329CAF65	FASTA	599	69,843
	10 20 30 40 50 60 MALKVLSVAT QMAIPSNLTT CLQPSHFKSS PKLLSSTNSS SRSRLRVYCS SSQLTTERRS 70 80 90 100 110 120 GNYNPSRWDV NFIQSLLSDY KEDKHVIRAS ELVTLVKMEL EKETDQIRQL ELIDDLQRMG 130 140 150 160 170 180 LSDHFQNEFK EILSSIYLDH HYYKNPFPKE ERDLYSTSLA FRLLREHGFQ VAQEVFDSFK 190 200 210 220 230 240 NEEGEFKESL SDDTRGLLQL YEASFLLTEG ETTLESAREF ATKFLEEKVN EGGVDGDLLT 250 260 270 280 290 300 RIAYSLDIPL HWRIKRPNAP VWIEWYRKRP DMNPVVLELA ILDLNIVQAQ FQEELKESFR 310 320 330 340 350 360 WWRNTGFVEK LPFARDRLVE CYFWNTGIIE PRQHASARIM MGKVNALITV IDDIYDVYGT 370 380 390 400 410 420 LEELEQFTDL IRRWDINSID QLPDYMQLCF LALNNFVDDT SYDVMKEKGV NVIPYLRQSW 430 440 450 460 470 480 VDLADKYMVE ARWFYGGHKP SLEEYLENSW QSISGPCMLT HIFFRVTDSF TKETVDSLYK 490 500 510 520 530 540 YHDLVRWSSF VLRLADDLGT SVEEVSRGDV PKSLQCYMSD YNASEAEARK HVKWLIAEVW 550 560 570 580 590 KKMNAERVSK DSPFGKDFIG CAVDLGRMAQ LMYHNGDGHG TQHPIIHQQM TRTLFEPFA

References

[1]	"4S-limonene synthase from the oil glands of spearmint (Mentha spicata). cDNA isolation, characterization, and bacterial expression of the catalytically active monoterpene cyclase." Colby S.M., Alonso W.R., Katahira E.J., McGarvey D.J., Croteau R. J. Biol. Chem. 268:23016-23024(1993) [PubMed: 8226816] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Leaf EMBL AAC37366.1.
[2]	"Structure of limonene synthase, a simple model for terpenoid cyclase catalysis." Hyatt D.C., Youn B., Zhao Y., Santhamma B., Coates R.M., Croteau R.B., Kang C. Proc. Natl. Acad. Sci. U.S.A. 104:5360-5365(2007) [PubMed: 17372193] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.70 ANGSTROMS) OF 58-599.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

L13459 mRNA. Translation: AAC37366.1.

PIR

A48863.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2ONG	X-ray	2.70	A/B	58-599	[»]
2ONH	X-ray	2.70	A/B	58-599	[»]

ProteinModelPortal

Q40322.

SMR

Q40322. Positions 58-598.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

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Family and domain databases

InterPro

IPR001906. Terpene_synth-like.
IPR005630. Terpene_synthase_metal-bd.
IPR008930. Terpenoid_cyclase/PrenylTrfase.
IPR008949. Terpenoid_synth.
[Graphical view]

Gene3D

G3DSA:1.50.30.10. Terpene_synth. 1 hit.
G3DSA:1.10.600.10. Terpenoid_synth. 1 hit.

Pfam

PF01397. Terpene_synth. 1 hit.
PF03936. Terpene_synth_C. 1 hit.
[Graphical view]

SUPFAM

SSF48239. Terp_cyc_toroid. 1 hit.
SSF48576. Terpenoid_synth. 1 hit.

ProtoNet

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Entry information

Entry name

Q40322_MENSP

Accession

Primary (citable) accession number: Q40322

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	July 27, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)