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Protein
Submitted name:

Chalcone reductase

Gene

CHR

Organism
Medicago sativa (Alfalfa)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei53NADPCombined sources1
Active sitei58Proton donorUniRule annotation1
Binding sitei58NADPCombined sources1
Binding sitei87NADPCombined sources1
Sitei87Lowers pKa of active site TyrUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei188NADPCombined sources1
Binding sitei263NADP; via amide nitrogenCombined sources1
Binding sitei269NADPCombined sources1
Binding sitei273NADPCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi27 – 30NADPCombined sources4
Nucleotide bindingi166 – 167NADPCombined sources2
Nucleotide bindingi214 – 219NADPCombined sources6

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Chalcone reductaseImported
Gene namesi
Name:CHRImported
OrganismiMedicago sativa (Alfalfa)Imported
Taxonomic identifieri3879 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago

PTM / Processingi

Proteomic databases

PRIDEiQ40309.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ZGDX-ray1.70A/B1-312[»]
ProteinModelPortaliQ40309.
SMRiQ40309.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ40309.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 292Aldo_ket_redInterPro annotationAdd BLAST262

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q40309-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSVEIPTKV LTNTSSQLKM PVVGMGSAPD FTCKKDTKDA IIEAIKQGYR
60 70 80 90 100
HFDTAAAYGS EQALGEALKE AIELGLVTRD DLFVTSKLWV TENHPHLVIP
110 120 130 140 150
ALQKSLKTLQ LDYLDLYLIH WPLSSQPGKF SFPIDVADLL PFDVKGVWES
160 170 180 190 200
MEESLKLGLT KAIGVSNFSV KKLENLLSVA TVLPAVNQVE MNLAWQQKKL
210 220 230 240 250
REFCNAHGIV LTAFSPVRKG ASRGPNEVME NDMLKEIADA HGKSVAQISL
260 270 280 290 300
RWLYEQGVTF VPKSYDKERM NQNLRIFDWS LTKEDHEKIA QIKQNRLIPG
310
PTKPGLNDLY DD
Length:312
Mass (Da):34,893
Last modified:November 1, 1996 - v1
Checksum:iBA68E76644FF60D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U13924 mRNA. Translation: AAB41555.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U13924 mRNA. Translation: AAB41555.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ZGDX-ray1.70A/B1-312[»]
ProteinModelPortaliQ40309.
SMRiQ40309.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ40309.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ40309.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 2 hits.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ40309_MEDSA
AccessioniPrimary (citable) accession number: Q40309
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.