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Protein

Anthocyanidin 3-O-glucosyltransferase 6

Gene

GT6

Organism
Manihot esculenta (Cassava) (Jatropha manihot)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments (By similarity). May be involved in glycosylation of unstable cyanohydrins to produce stable cyanoglucosides.By similarity

Catalytic activityi

UDP-D-glucose + an anthocyanidin = UDP + an anthocyanidin-3-O-beta-D-glucoside.

Pathwayi: anthocyanin biosynthesis

This protein is involved in the pathway anthocyanin biosynthesis, which is part of Pigment biosynthesis.
View all proteins of this organism that are known to be involved in the pathway anthocyanin biosynthesis and in Pigment biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00009.

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Anthocyanidin 3-O-glucosyltransferase 6 (EC:2.4.1.115)
Alternative name(s):
Flavonol 3-O-glucosyltransferase 6
UDP-glucose flavonoid 3-O-glucosyltransferase 6
Gene namesi
Name:GT6
Synonyms:UGT73A6
OrganismiManihot esculenta (Cassava) (Jatropha manihot)
Taxonomic identifieri3983 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeCrotonoideaeManihoteaeManihot

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 394›394Anthocyanidin 3-O-glucosyltransferase 6PRO_0000074147Add
BLAST

Expressioni

Tissue specificityi

Expressed in cotyledons and leaves.

Developmental stagei

Expressed primarily in developing cotyledons (from emerging green cotyledons to approximately 10 days old); very low levels in hypocotyls and no measurable expression in roots.

Structurei

3D structure databases

ProteinModelPortaliQ40288.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q40288-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DDFKDLGFID KQKAHVKEAV SKLTARSDSS LAGFVLDMFC TSMIDVAKEL
60 70 80 90 100
GVPYYIFFTS GAAFLGFLFY VQLIHDEQDA DLTQFKDSDA ELSVPSLANS
110 120 130 140 150
LPARVLPASM LVKDRFYAFI RIIRGLREAK GIMVNTFMEL ESHALNSLKD
160 170 180 190 200
DQSKIPPIYP VGPILKLSNQ ENDVGPEGSE IIEWLDDQPP SSVVFLCFGS
210 220 230 240 250
MGGFDMDQAK EIACALEQSR HRFLWSLRRP PPKGKIETST DYENLQEILP
260 270 280 290 300
VGFSERTAGM GKVVGWAPQV AILEHPAIGG FVSHCGWNSI LESIWFSVPI
310 320 330 340 350
ATWPLYAEQQ FNAFTMVTEL GLAVEIKMDY KKESEIILSA DDIERGIKCV
360 370 380 390
MEHHSEIRKR VKEMSDKSRK ALMDDESSSF WLDRLIEDVI NNLS
Length:394
Mass (Da):44,265
Last modified:November 1, 1997 - v1
Checksum:iFD51CD974E5ADCD7
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77463 mRNA. Translation: CAA54613.1.
PIRiS41952.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77463 mRNA. Translation: CAA54613.1.
PIRiS41952.

3D structure databases

ProteinModelPortaliQ40288.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00009.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Multiple secondary plant product UDP-glucose glucosyltransferase genes expressed in cassava (Manihot esculenta Crantz) cotyledons."
    Hughes J., Hughes M.A.
    DNA Seq. 5:41-49(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Cotyledon.

Entry informationi

Entry nameiUFOG6_MANES
AccessioniPrimary (citable) accession number: Q40288
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 11, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.