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Protein

Major allergen Mal d 1

Gene
N/A
Organism
Malus domestica (Apple) (Pyrus malus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionPathogenesis-related protein
Biological processPlant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Major allergen Mal d 1
Alternative name(s):
AP15
Allergen Mal d I
Allergen: Mal d 1
OrganismiMalus domestica (Apple) (Pyrus malus)
Taxonomic identifieri3750 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeAmygdaloideaeMaleaeMalus

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei1456 Mal d 1.0201
1461 Mal d 1.0206
464 Mal d 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001541912 – 159Major allergen Mal d 1Add BLAST158

Structurei

3D structure databases

ProteinModelPortaliQ40280
SMRiQ40280
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the BetVI family.Curated

Family and domain databases

Gene3Di3.30.530.20, 1 hit
InterProiView protein in InterPro
IPR000916 Bet_v_I/MLP
IPR024949 Bet_v_I_allergen
IPR023393 START-like_dom_sf
PfamiView protein in Pfam
PF00407 Bet_v_1, 1 hit
PRINTSiPR00634 BETALLERGEN
PROSITEiView protein in PROSITE
PS00451 PATHOGENESIS_BETVI, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q40280-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVYTFENEY TSEIPPPRLF KAFVLDADNL IPKIAPQAIK HAEILEGDGG
60 70 80 90 100
PGTIKKITFG EGSQYGYVKH KIDSVDEANY SYAYTLIEGD ALTDTIEKVS
110 120 130 140 150
YETKLVASGS GSIIKSISHY HTKGDVEIKE EHVKAGKEKA HGLFKLIESY

LKGHPDAYN
Length:159
Mass (Da):17,539
Last modified:January 23, 2007 - v3
Checksum:i7332100D2C614446
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti22A → G. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42952 mRNA Translation: AAB01362.1
AF074721 mRNA Translation: AAC26136.1
AF020542 Genomic DNA Translation: AAD13683.1
RefSeqiNP_001281292.1, NM_001294363.1
UniGeneiMdo.3014

Genome annotation databases

GeneIDi103425638
KEGGimdm:103425638

Similar proteinsi

Entry informationi

Entry nameiMAL12_MALDO
AccessioniPrimary (citable) accession number: Q40280
Secondary accession number(s): O22517
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 68 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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