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Protein

Major pollen allergen Lol p 5a

Gene

LOLPIB

Organism
Lolium perenne (Perennial ryegrass)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Lol p 5a
Alternative name(s):
Allergen Lol p Ib
Allergen Lol p Va
Allergen: Lol p 5a
Gene namesi
Name:LOLPIB
OrganismiLolium perenne (Perennial ryegrass)
Taxonomic identifieri4522 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaePoodaePoeaePoeae Chloroplast Group 2 (Poeae type)LoliinaeLolium

Subcellular locationi


    Note: Starch granule.

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei460. Lol p 5.
462. Lol p 5.0102.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000002174326 – 307Major pollen allergen Lol p 5aAdd BLAST282

Expressioni

Tissue specificityi

Pollen, starch granules.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi31 – 48Ala/Pro/Thr-richAdd BLAST18
Compositional biasi269 – 288Ala/Thr-richAdd BLAST20
Compositional biasi269 – 277Poly-Ala9

Sequence similaritiesi

Belongs to the Poa p IX/Phl p VI allergen family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di1.20.120.320. 2 hits.
InterProiIPR002914. Poa_pIX/Phl_pVI.
[Graphical view]
PfamiPF01620. Pollen_allerg_2. 2 hits.
[Graphical view]
SUPFAMiSSF81736. SSF81736. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q40240-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVQKYTVAL FLAVALVAGP AASYAADAGY TPAAAATPAT PAATPAAAGG
60 70 80 90 100
KATTDEQKLL EDVNAGFKAA VAAAANAPPA DKFKIFEAAF SESSKGLLAT
110 120 130 140 150
SAAKAPGLIP KLDTAYDVAY KAAEATPEAK YDAFVTALTE ALRVIAGALE
160 170 180 190 200
VHAVKPATEE VLAAKIPTGE LQIVDKIDAA FKIAATAANA APTNDKFTVF
210 220 230 240 250
ESAFNKALNE CTGGAYETYK FIPSLEAAVK QAYAATVAAA PEVKYAVFEA
260 270 280 290 300
ALTKAITAMT QAQKAGKPAA AAATAAATVA TAAATAAAVL PPPLLVVQSL

ISLLIYY
Length:307
Mass (Da):30,887
Last modified:May 3, 2011 - v2
Checksum:i926645E57F1B6952
GO

Sequence cautioni

The sequence AAA33406 differs from that shown. Reason: Frameshift at several positions.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M59163 mRNA. Translation: AAA33406.1. Frameshift.
PIRiA38582.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M59163 mRNA. Translation: AAA33406.1. Frameshift.
PIRiA38582.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei460. Lol p 5.
462. Lol p 5.0102.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.120.320. 2 hits.
InterProiIPR002914. Poa_pIX/Phl_pVI.
[Graphical view]
PfamiPF01620. Pollen_allerg_2. 2 hits.
[Graphical view]
SUPFAMiSSF81736. SSF81736. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiMPA5A_LOLPR
AccessioniPrimary (citable) accession number: Q40240
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 3, 2011
Last modified: February 17, 2016
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.