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Q40237

- MPA5B_LOLPR

UniProt

Q40237 - MPA5B_LOLPR

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Protein

Major pollen allergen Lol p 5b

Gene
N/A
Organism
Lolium perenne (Perennial ryegrass)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Biological processi

  1. type I hypersensitivity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Major pollen allergen Lol p 5b
Alternative name(s):
Allergen Lol p Vb
Allergen: Lol p 5b
OrganismiLolium perenne (Perennial ryegrass)
Taxonomic identifieri4522 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaePoeaeLoliinaeLolium

Organism-specific databases

GrameneiQ40237.

Subcellular locationi


Note: Starch granule.By similarity

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Causes grass pollen allergy.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei460. Lol p 5.
461. Lol p 5.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence AnalysisAdd
BLAST
Chaini26 – 339314Major pollen allergen Lol p 5bPRO_0000021745Add
BLAST

Expressioni

Tissue specificityi

Pollen, starch granules.

Structurei

3D structure databases

ProteinModelPortaliQ40237.
SMRiQ40237. Positions 64-173, 185-283.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati32 – 3431-1
Repeati35 – 3731-2
Repeati38 – 4031-3
Repeati41 – 4331-4
Repeati44 – 4631-5
Repeati47 – 4931-6
Repeati50 – 5231-7
Repeati53 – 5531-8
Repeati56 – 5831-9
Repeati285 – 29062-1; truncated
Repeati292 – 30092-2
Repeati301 – 30992-3
Repeati310 – 31892-4
Repeati319 – 32792-5
Repeati328 – 33472-6; truncated

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni32 – 58279 X 3 AA tandem repeats of [PA]-A-[TA]Add
BLAST
Regioni285 – 334506 X 9 AA approximate tandem repeats of T-A-T-A-T-P-A-A-AAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi81 – 877Poly-Ala
Compositional biasi288 – 2936Poly-Ala

Sequence similaritiesi

Belongs to the Poa p IX/Phl p VI allergen family.Curated

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3Di1.20.120.320. 2 hits.
InterProiIPR001778. POA_allergen.
IPR002914. POA_allergen_N.
[Graphical view]
PfamiPF01620. Pollen_allerg_2. 2 hits.
[Graphical view]
PRINTSiPR00833. POAALLERGEN.
SUPFAMiSSF81736. SSF81736. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q40237-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVQKHTVAL FLAVALVAGP AASYAADAGY APATPATPAA PATAATPATP
60 70 80 90 100
ATPATPAAVP SGKATTEEQK LIEKINAGFK AAVAAAAVVP PADKYKTFVE
110 120 130 140 150
TFGTATNKAF VEGLASGYAD QSKNQLTSKL DAALKLAYEA AQGATPEAKY
160 170 180 190 200
DAYVATLTEA LRVIAGTLEV HAVKPAAEEV KVGAIPAAEV QLIDKVDAAY
210 220 230 240 250
RTAATAANAA PANDKFTVFE NTFNNAIKVS LGAAYDSYKF IPTLVAAVKQ
260 270 280 290 300
AYAAKQATAP EVKYTVSETA LKKAVTAMSE AEKEATPAAA ATATPTPAAA
310 320 330
TATATPAAAY ATATPAAATA TATPAAATAT PAAAGGYKV
Length:339
Mass (Da):33,750
Last modified:November 1, 1996 - v1
Checksum:i3CAA3115625E0610
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13083 mRNA. Translation: AAA33405.1.
PIRiJT0756.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13083 mRNA. Translation: AAA33405.1 .
PIRi JT0756.

3D structure databases

ProteinModelPortali Q40237.
SMRi Q40237. Positions 64-173, 185-283.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 460. Lol p 5.
461. Lol p 5.0101.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei Q40237.

Family and domain databases

Gene3Di 1.20.120.320. 2 hits.
InterProi IPR001778. POA_allergen.
IPR002914. POA_allergen_N.
[Graphical view ]
Pfami PF01620. Pollen_allerg_2. 2 hits.
[Graphical view ]
PRINTSi PR00833. POAALLERGEN.
SUPFAMi SSF81736. SSF81736. 2 hits.
ProtoNeti Search...

Publicationsi

  1. "Cloning of a cDNA encoding a group-V (group-IX) allergen isoform from rye-grass pollen that demonstrates specific antigenic immunoreactivity."
    Ong E.K., Griffith I.J., Knox R.B., Singh M.B.
    Gene 134:235-240(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Pollen.

Entry informationi

Entry nameiMPA5B_LOLPR
AccessioniPrimary (citable) accession number: Q40237
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 1, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3