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Q40237

- MPA5B_LOLPR

UniProt

Q40237 - MPA5B_LOLPR

Protein

Major pollen allergen Lol p 5b

Gene
N/A
Organism
Lolium perenne (Perennial ryegrass)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. type I hypersensitivity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Major pollen allergen Lol p 5b
    Alternative name(s):
    Allergen Lol p Vb
    Allergen: Lol p 5b
    OrganismiLolium perenne (Perennial ryegrass)
    Taxonomic identifieri4522 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaePoeaeLoliinaeLolium

    Organism-specific databases

    GrameneiQ40237.

    Subcellular locationi


    Note: Starch granule.By similarity

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human. Causes grass pollen allergy.

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei460. Lol p 5.
    461. Lol p 5.0101.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 339314Major pollen allergen Lol p 5bPRO_0000021745Add
    BLAST

    Expressioni

    Tissue specificityi

    Pollen, starch granules.

    Structurei

    3D structure databases

    ProteinModelPortaliQ40237.
    SMRiQ40237. Positions 64-173, 185-283.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati32 – 3431-1
    Repeati35 – 3731-2
    Repeati38 – 4031-3
    Repeati41 – 4331-4
    Repeati44 – 4631-5
    Repeati47 – 4931-6
    Repeati50 – 5231-7
    Repeati53 – 5531-8
    Repeati56 – 5831-9
    Repeati285 – 29062-1; truncated
    Repeati292 – 30092-2
    Repeati301 – 30992-3
    Repeati310 – 31892-4
    Repeati319 – 32792-5
    Repeati328 – 33472-6; truncated

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni32 – 58279 X 3 AA tandem repeats of [PA]-A-[TA]Add
    BLAST
    Regioni285 – 334506 X 9 AA approximate tandem repeats of T-A-T-A-T-P-A-A-AAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi81 – 877Poly-Ala
    Compositional biasi288 – 2936Poly-Ala

    Sequence similaritiesi

    Belongs to the Poa p IX/Phl p VI allergen family.Curated

    Keywords - Domaini

    Repeat, Signal

    Family and domain databases

    Gene3Di1.20.120.320. 2 hits.
    InterProiIPR001778. POA_allergen.
    IPR002914. POA_allergen_N.
    [Graphical view]
    PfamiPF01620. Pollen_allerg_2. 2 hits.
    [Graphical view]
    PRINTSiPR00833. POAALLERGEN.
    SUPFAMiSSF81736. SSF81736. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q40237-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVQKHTVAL FLAVALVAGP AASYAADAGY APATPATPAA PATAATPATP    50
    ATPATPAAVP SGKATTEEQK LIEKINAGFK AAVAAAAVVP PADKYKTFVE 100
    TFGTATNKAF VEGLASGYAD QSKNQLTSKL DAALKLAYEA AQGATPEAKY 150
    DAYVATLTEA LRVIAGTLEV HAVKPAAEEV KVGAIPAAEV QLIDKVDAAY 200
    RTAATAANAA PANDKFTVFE NTFNNAIKVS LGAAYDSYKF IPTLVAAVKQ 250
    AYAAKQATAP EVKYTVSETA LKKAVTAMSE AEKEATPAAA ATATPTPAAA 300
    TATATPAAAY ATATPAAATA TATPAAATAT PAAAGGYKV 339
    Length:339
    Mass (Da):33,750
    Last modified:November 1, 1996 - v1
    Checksum:i3CAA3115625E0610
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L13083 mRNA. Translation: AAA33405.1.
    PIRiJT0756.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L13083 mRNA. Translation: AAA33405.1 .
    PIRi JT0756.

    3D structure databases

    ProteinModelPortali Q40237.
    SMRi Q40237. Positions 64-173, 185-283.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 460. Lol p 5.
    461. Lol p 5.0101.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei Q40237.

    Family and domain databases

    Gene3Di 1.20.120.320. 2 hits.
    InterProi IPR001778. POA_allergen.
    IPR002914. POA_allergen_N.
    [Graphical view ]
    Pfami PF01620. Pollen_allerg_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00833. POAALLERGEN.
    SUPFAMi SSF81736. SSF81736. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of a cDNA encoding a group-V (group-IX) allergen isoform from rye-grass pollen that demonstrates specific antigenic immunoreactivity."
      Ong E.K., Griffith I.J., Knox R.B., Singh M.B.
      Gene 134:235-240(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Pollen.

    Entry informationi

    Entry nameiMPA5B_LOLPR
    AccessioniPrimary (citable) accession number: Q40237
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3