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Protein

Heat shock factor protein HSF8

Gene

HSF8

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi39 – 133By similarityAdd BLAST95

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Stress response, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock factor protein HSF8
Alternative name(s):
Heat shock transcription factor 8
Short name:
HSTF 8
Heat stress transcription factor
Gene namesi
Name:HSF8
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon
Proteomesi
  • UP000004994 Componenti: Chromosome 8

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001245911 – 527Heat shock factor protein HSF8Add BLAST527

Post-translational modificationi

Exhibits temperature-dependent phosphorylation.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ40152.

Interactioni

Subunit structurei

Homotrimer.By similarity

Protein-protein interaction databases

STRINGi4081.Solyc08g005170.2.1.

Structurei

3D structure databases

ProteinModelPortaliQ40152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi137 – 141Poly-Gln5
Compositional biasi193 – 196Poly-Gln4

Sequence similaritiesi

Belongs to the HSF family.Curated

Phylogenomic databases

eggNOGiKOG0627. Eukaryota.
COG5169. LUCA.
InParanoidiQ40152.
KOiK09419.
OMAiKPAHGHA.
OrthoDBiEOG09360BUI.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000232. HSF_DNA-bd.
IPR027725. HSF_fam.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10015. PTHR10015. 2 hits.
PfamiPF00447. HSF_DNA-bind. 1 hit.
[Graphical view]
PRINTSiPR00056. HSFDOMAIN.
SMARTiSM00415. HSF. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00434. HSF_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q40152-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPNSYGSGK AAVGDGVGAP MLQTAPAPAP IPSANAPPPF LVKTYDMVDD
60 70 80 90 100
PSTDKIVSWS PTNNSFVVWD PPEFAKDLLP KYFKHNNFSS FVRQLNTYGF
110 120 130 140 150
RKVDPDRWEF ANEGFLRGQK HLLKSISRRK PAHGHAQQQQ QPHGNAQQQM
160 170 180 190 200
QPPGHSASVG ACVEVGKFGL EEEVERLKRD KNVLMQELVR LRQQQQATDN
210 220 230 240 250
QLQGMVQRLQ GMELRQQQMM SFLAKAVNRP GFLAQFVQQQ NESNKRIAEG
260 270 280 290 300
SKKRRIKQDI ESQDPSVTPA DGQIVKYQPG INEAAKAMLR ELSKLDSSPR
310 320 330 340 350
LDNFSNSPES FLIGDGSPQS NASSGRVSGV TLQEVPPTSG KPLLNTASAI
360 370 380 390 400
AGQSLLPATS EMQSSHLGTC SEIINNQLSN IIPLVGGEDL HPGSLSASDM
410 420 430 440 450
IMPELSQLQG ILPENNTDVI GCDSFMDTSA VEGKVGLDII GSCLSPGADI
460 470 480 490 500
DWQSGLLDEI EEFPSVGDPF WEKFLQSPCS PDAAMDDDIS NTSETKPQIN
510 520
GWDKTQNMEH LTEQMGATNI KQQKHMI
Length:527
Mass (Da):57,701
Last modified:November 1, 1996 - v1
Checksum:i357EC1605C6C0C0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67599 Genomic DNA. Translation: CAA47868.1.
PIRiS25478.
RefSeqiNP_001296177.1. NM_001309248.1.

Genome annotation databases

EnsemblPlantsiSolyc08g005170.2.1; Solyc08g005170.2.1; Solyc08g005170.2.
GeneIDi101263626.
GrameneiSolyc08g005170.2.1; Solyc08g005170.2.1; Solyc08g005170.2.
KEGGisly:101263626.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X67599 Genomic DNA. Translation: CAA47868.1.
PIRiS25478.
RefSeqiNP_001296177.1. NM_001309248.1.

3D structure databases

ProteinModelPortaliQ40152.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4081.Solyc08g005170.2.1.

Proteomic databases

PaxDbiQ40152.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiSolyc08g005170.2.1; Solyc08g005170.2.1; Solyc08g005170.2.
GeneIDi101263626.
GrameneiSolyc08g005170.2.1; Solyc08g005170.2.1; Solyc08g005170.2.
KEGGisly:101263626.

Phylogenomic databases

eggNOGiKOG0627. Eukaryota.
COG5169. LUCA.
InParanoidiQ40152.
KOiK09419.
OMAiKPAHGHA.
OrthoDBiEOG09360BUI.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000232. HSF_DNA-bd.
IPR027725. HSF_fam.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10015. PTHR10015. 2 hits.
PfamiPF00447. HSF_DNA-bind. 1 hit.
[Graphical view]
PRINTSiPR00056. HSFDOMAIN.
SMARTiSM00415. HSF. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS00434. HSF_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSF8_SOLLC
AccessioniPrimary (citable) accession number: Q40152
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.