Q40059 (Q40059_HORVU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Chymotrypsin inhibitor 2 EMBL CAA40350.1

Gene names

Name:

Ica-2 EMBL CAA40350.1

Organism

Hordeum vulgare (Barley) EMBL CAA40350.1

Taxonomic identifier

4513 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Hordeum

Protein attributes

Sequence length	84 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1TM4 PDB 1TM5 PDB 1TM3 PDB 1TO2 PDB 1TM7 PDB 1TO1 PDB 1TM1 PDB 1TMG PDB 1Y4A PDB 1Y3B PDB 1Y3F PDB 1Y3D PDB 1Y3C PDB 1Y4D PDB 1Y1K PDB 1Y48 PDB 1Y33 PDB 1Y34
Gene Ontology (GO)
Biological process	response to wounding Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction Ref.2. Source: IntAct serine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
apr	P00782	8	EBI-1040468,EBI-1033955	From a different organism.

Sequences

	Sequence		Length	Mass (Da)
	Q40059 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 8EC2742E5B01D644	FASTA	84	9,401
	10 20 30 40 50 60 MSSMEKKPEG VNIGAGDRQN QKTEWPELVG KSVEEAKKVI LQDKPAAQII VLPVGTIVTM 70 80 EYRIDRVRLF VDRLDNIAQV PRVG

References

[1]	"Nucleotide Sequence of a Chymotrypsin Inhibitor-2 Gene of Barley (Hordeum vulgare L.)." Peterson D.M., Forde J., Williamson M., Rohde W., Kreis M. Plant Physiol. 96:1389-1390(1991) [PubMed: 16668350] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Vogelsaenger Gold EMBL CAA40350.1.
[2]	"Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN'/chymotrypsin inhibitor 2 complex." Radisky E.S., Kwan G., Karen Lu C.J., Koshland D.E. Jr Biochemistry 43:13648-13656(2004) [PubMed: 15504027] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS) OF 22-84.
[3]	"Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2." Radisky E.S., Lu C.J., Kwan G., Koshland D.E. Biochemistry 44:6823-6830(2005) [PubMed: 15865427] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 22-84.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X57035 Genomic DNA. Translation: CAA40350.1.

PIR

S18818.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1TM1	X-ray	1.70	I	22-84	[»]
1TM3	X-ray	1.57	I	22-84	[»]
1TM4	X-ray	1.70	I	22-84	[»]
1TM5	X-ray	1.45	I	22-83	[»]
1TM7	X-ray	1.59	I	22-84	[»]
1TMG	X-ray	1.67	I	22-84	[»]
1TO1	X-ray	1.68	I	22-84	[»]
1TO2	X-ray	1.30	I	22-84	[»]
1Y1K	X-ray	1.56	I	22-84	[»]
1Y33	X-ray	1.80	I	22-84	[»]
1Y34	X-ray	1.55	I	22-84	[»]
1Y3B	X-ray	1.80	I	22-84	[»]
1Y3C	X-ray	1.69	I	22-84	[»]
1Y3D	X-ray	1.80	I	22-84	[»]
1Y3F	X-ray	1.72	I	22-84	[»]
1Y48	X-ray	1.84	I	22-84	[»]
1Y4A	X-ray	1.60	I	22-84	[»]
1Y4D	X-ray	2.00	I	22-84	[»]

ProteinModelPortal

Q40059.

SMR

Q40059. Positions 22-84.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q40059. 1 interaction.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Organism-specific databases

Gramene

Q40059.

Gene expression databases

Genevestigator

Q40059.

Family and domain databases

InterPro

IPR000864. Prot_inh_pot1.
[Graphical view]

Gene3D

G3DSA:3.30.10.10. Prot_inh_pot1. 1 hit.

Pfam

PF00280. potato_inhibit. 1 hit.
[Graphical view]

PRINTS

PR00292. POTATOINHBTR.

ProDom

PD002604. Prot_inh_pot1. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SUPFAM

SSF54654. Prot_inh_pot1. 1 hit.

PROSITE

PS00285. POTATO_INHIBITOR. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q40059_HORVU

Accession

Primary (citable) accession number: Q40059

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	October 19, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)