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Protein
Submitted name:

Chymotrypsin inhibitor 2

Gene

Ica-2

Organism
Hordeum vulgare (Barley)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Chymotrypsin inhibitor 2Imported
Gene namesi
Name:Ica-2Imported
OrganismiHordeum vulgare (Barley)Imported
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeHordeinaeHordeum

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
aprP007828EBI-1040468,EBI-1033955From a different organism.

Protein-protein interaction databases

IntActiQ40059. 1 interaction.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TM1X-ray1.70I22-84[»]
1TM3X-ray1.57I22-84[»]
1TM4X-ray1.70I22-84[»]
1TM5X-ray1.45I22-83[»]
1TM7X-ray1.59I22-84[»]
1TMGX-ray1.67I22-84[»]
1TO1X-ray1.68I22-84[»]
1TO2X-ray1.30I22-84[»]
1Y1KX-ray1.56I22-84[»]
1Y33X-ray1.80I22-84[»]
1Y34X-ray1.55I22-84[»]
1Y3BX-ray1.80I22-84[»]
1Y3CX-ray1.69I22-84[»]
1Y3DX-ray1.80I22-84[»]
1Y3FX-ray1.72I22-84[»]
1Y48X-ray1.84I22-84[»]
1Y4AX-ray1.60I22-84[»]
1Y4DX-ray2.00I22-84[»]
ProteinModelPortaliQ40059.
SMRiQ40059. Positions 22-84.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ40059.

Family & Domainsi

Family and domain databases

InterProiIPR000864. Prot_inh_pot1.
[Graphical view]
PfamiPF00280. potato_inhibit. 1 hit.
[Graphical view]
PRINTSiPR00292. POTATOINHBTR.
ProDomiPD002604. Prot_inh_pot1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54654. SSF54654. 1 hit.
PROSITEiPS00285. POTATO_INHIBITOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q40059-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSMEKKPEG VNIGAGDRQN QKTEWPELVG KSVEEAKKVI LQDKPAAQII
60 70 80
VLPVGTIVTM EYRIDRVRLF VDRLDNIAQV PRVG
Length:84
Mass (Da):9,401
Last modified:November 1, 1996 - v1
Checksum:i8EC2742E5B01D644
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57035 Genomic DNA. Translation: CAA40350.1.
PIRiS18818.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57035 Genomic DNA. Translation: CAA40350.1.
PIRiS18818.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TM1X-ray1.70I22-84[»]
1TM3X-ray1.57I22-84[»]
1TM4X-ray1.70I22-84[»]
1TM5X-ray1.45I22-83[»]
1TM7X-ray1.59I22-84[»]
1TMGX-ray1.67I22-84[»]
1TO1X-ray1.68I22-84[»]
1TO2X-ray1.30I22-84[»]
1Y1KX-ray1.56I22-84[»]
1Y33X-ray1.80I22-84[»]
1Y34X-ray1.55I22-84[»]
1Y3BX-ray1.80I22-84[»]
1Y3CX-ray1.69I22-84[»]
1Y3DX-ray1.80I22-84[»]
1Y3FX-ray1.72I22-84[»]
1Y48X-ray1.84I22-84[»]
1Y4AX-ray1.60I22-84[»]
1Y4DX-ray2.00I22-84[»]
ProteinModelPortaliQ40059.
SMRiQ40059. Positions 22-84.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ40059. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ40059.

Family and domain databases

InterProiIPR000864. Prot_inh_pot1.
[Graphical view]
PfamiPF00280. potato_inhibit. 1 hit.
[Graphical view]
PRINTSiPR00292. POTATOINHBTR.
ProDomiPD002604. Prot_inh_pot1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54654. SSF54654. 1 hit.
PROSITEiPS00285. POTATO_INHIBITOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide Sequence of a Chymotrypsin Inhibitor-2 Gene of Barley (Hordeum vulgare L.)."
    Peterson D.M., Forde J., Williamson M., Rohde W., Kreis M.
    Plant Physiol. 96:1389-1390(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Vogelsaenger GoldImported.
  2. "Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN'/chymotrypsin inhibitor 2 complex."
    Radisky E.S., Kwan G., Karen Lu C.J., Koshland D.E.
    Biochemistry 43:13648-13656(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.30 ANGSTROMS) OF 22-84.
  3. "Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2."
    Radisky E.S., Lu C.J., Kwan G., Koshland D.E.
    Biochemistry 44:6823-6830(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 22-84.

Entry informationi

Entry nameiQ40059_HORVU
AccessioniPrimary (citable) accession number: Q40059
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 13, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.