Q3ZZ13 (TRPF_DEHSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	cbdbA1447

Organism

Dehalococcoides sp. (strain CBDB1) [Complete proteome] [HAMAP]

Taxonomic identifier

255470 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chloroflexi › Dehalococcoidetes › Dehalococcoidales › Dehalococcoidaceae › Dehalococcoides › Dehalococcoides mccartyi

Protein attributes

Sequence length	219 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 219	219	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000018592

Sequences

	Sequence		Length	Mass (Da)
	Q3ZZ13 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: A07066BA5B10D916	FASTA	219	23,829
	10 20 30 40 50 60 MIKTKICGLT EVGQALATAR TGADFAGVVF AESKRRITTE KALEIAEALK PLNPRPMLVG 70 80 90 100 110 120 VFANQTAEEV NRIASVCRLD RVQLSGNESW EYCNQVNLPV IKVIHVAEST TAELVIQEIQ 130 140 150 160 170 180 AGLKALKKTP VFLLDTHTKA LFGGSGQSFD WQIVKQVSLK YPVMVAGGLN PENIQGFIKI 190 200 210 AKPWGIDVAS GVETDGIKDT AKIHLFIERV KDADGNRIC

References

[1]

"Genome sequence of the chlorinated compound-respiring bacterium Dehalococcoides species strain CBDB1." Kube M., Beck A., Zinder S.H., Kuhl H., Reinhardt R., Adrian L. Nat. Biotechnol. 23:1269-1273(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CBDB1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ965256 Genomic DNA. Translation: CAI83475.1.
RefSeq	YP_308391.1. NC_007356.1.
3D structure databases
ProteinModelPortal	Q3ZZ13.
ModBase	Search...
Protein-protein interaction databases
STRING	255470.cbdb_A1447.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI83475; CAI83475; cbdbA1447.
GeneID	3623812.
KEGG	deh:cbdb_A1447.
PATRIC	21612805. VBIDehSp125902_1210.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
KO	K01817.
OMA	PVIRAIQ.
ProtClustDB	CLSK836911.
Enzyme and pathway databases
BioCyc	DSP255470:GJXW-1242-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_DEHSC

Accession

Primary (citable) accession number: Q3ZZ13

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 27, 2005
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program