Q3ZYX0 (GCP_DEHSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	cbdbA1390

Organism

Dehalococcoides sp. (strain CBDB1) [Complete proteome] [HAMAP]

Taxonomic identifier

255470 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Dehalococcoidetes › Dehalococcoides

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 326	326	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303344

Sequences

	Sequence		Length	Mass (Da)
	Q3ZYX0 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: 670DE1DF54C39A1B	FASTA	326	34,264
	10 20 30 40 50 60 MKILGIESSC DETAASVVED GVNILSNRIS SQIDIHSRYG GVVPEVASRQ HLLSILPVIK 70 80 90 100 110 120 DALEEARTGL DEISAIAITN GPGLAGSLIV GVNAAKAIAA ARRIPLVAVN HLHGHIYANW 130 140 150 160 170 180 LFGKIPEFPC LCLTVSGGHT DLVLMSGHGQ YQLLGRTRDD AAGEAFDKAA RILGLSYPGG 190 200 210 220 230 240 PAIDRASQDG QAVLDLPRSW IPGSHDFSFS GLKTALLRLV ESGEVCSVND AAASFQKAVV 250 260 270 280 290 300 DVLVTKTINC AQEYNVKQIL LAGGVAANNL LRKQLSEKSS LPVSIPPMGL CTDNAAVIAS 310 320 CGYFRFISGK QDGLDMDVLP ALSVTS

References

[1]

"Genome sequence of the chlorinated compound-respiring bacterium Dehalococcoides species strain CBDB1." Kube M., Beck A., Zinder S.H., Kuhl H., Reinhardt R., Adrian L. Nat. Biotechnol. 23:1269-1273(2005) [PubMed: 16116419] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CBDB1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ965256 Genomic DNA. Translation: CAI83434.1.
RefSeq	YP_308350.1. NC_007356.1.
3D structure databases
ProteinModelPortal	Q3ZYX0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ZYX0.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3623597.
GenomeReviews	Gene locus cbdbA1390 in contig AJ965256_GR.
KEGG	deh:cbdb_A1390.
NMPDR	fig|255470.3.peg.1393.
PATRIC	21612703. VBIDehSp125902_1167.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PAVGVHH.
PhylomeDB	Q3ZYX0.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	DSP255470:CBDBA1390-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_DEHSC

Accession

Primary (citable) accession number: Q3ZYX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 27, 2005
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program