ID   COAE_DEHSC              Reviewed;         198 AA.
AC   Q3ZYN7;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 28.
DE   RecName: Full=Dephospho-CoA kinase;
DE            EC=2.7.1.24;
DE   AltName: Full=Dephosphocoenzyme A kinase;
GN   Name=coaE; OrderedLocusNames=cbdbA1268;
OS   Dehalococcoides sp. (strain CBDB1).
OC   Bacteria; Chloroflexi; Dehalococcoidetes; Dehalococcoides.
OX   NCBI_TaxID=255470;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16116419; DOI=10.1038/nbt1131;
RA   Kube M., Beck A., Zinder S.H., Kuhl H., Reinhardt R., Adrian L.;
RT   "Genome sequence of the chlorinated compound-respiring bacterium
RT   Dehalococcoides species strain CBDB1.";
RL   Nat. Biotechnol. 23:1269-1273(2005).
CC   -!- FUNCTION: Catalyzes the phosphorylation of the 3'-hydroxyl group
CC       of dephosphocoenzyme A to form coenzyme A (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = ADP + CoA.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 5/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the coaE family.
CC   -!- SIMILARITY: Contains 1 DPCK (dephospho-CoA kinase) domain.
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DR   EMBL; AJ965256; CAI83330.1; -; Genomic_DNA.
DR   RefSeq; YP_308246.1; -.
DR   GeneID; 3623657; -.
DR   GenomeReviews; AJ965256_GR; cbdbA1268.
DR   KEGG; deh:cbdb_A1268; -.
DR   NMPDR; fig|255470.3.peg.1102; -.
DR   HOGENOM; Q3ZYN7; -.
DR   OMA; Q3ZYN7; LHPMIRQ.
DR   BioCyc; DSP255470:CBDBA1268-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00376; -; 1.
DR   InterPro; IPR001977; Depp_CoAkinase.
DR   PANTHER; PTHR10695; Depp_CoAkinase; 1.
DR   Pfam; PF01121; CoaE; 1.
DR   ProDom; PD003329; Depp_CoAkinase; 1.
DR   TIGRFAMs; TIGR00152; Depp_CoAkinase; 1.
DR   PROSITE; PS51219; DPCK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    198       Dephospho-CoA kinase.
FT                                /FTId=PRO_0000243281.
FT   DOMAIN        3    198       DPCK.
FT   NP_BIND       8     15       ATP (Potential).
SQ   SEQUENCE   198 AA;  22234 MW;  AF328CC510B225FF CRC64;
     MKIVGITGGI GSGKTTVCRY LKELGVNIID ADEIGHRVLQ NKGIRTKITD VFGNEVMNPD
     GNINRKILGE LVFGYPERLE RLNKITHPLI EQAISSLLEE YRQKGIKSVA IEAPLLVEAG
     WLKLVNEVWL ITAPKESIFK RLHSRMGLSR EQAIARIQSQ ATDNERLKYA SVVVNNNCRF
     EDLKACVQLL AKERLELA
//