Q3ZYC8 (Q3ZYC8_DEHSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401 EMBL CAI83251.1
Ordered Locus Names:	cbdbA1161

Organism

Dehalococcoides sp. (strain CBDB1) [Complete proteome] [HAMAP]

Taxonomic identifier

255470 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Dehalococcoidetes › Dehalococcoides

Protein attributes

Sequence length	174 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL CAI83251.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	11	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q3ZYC8 [UniParc]. Last modified September 27, 2005. Version 1. Checksum: FAB83390816F0437	FASTA	174	19,487
	10 20 30 40 50 60 MNEIAVFGGG CFWCMEAVFS SLSGVTKVEP GYAGGNLPNP TYQQVCAGDT GHAEVIRLEF 70 80 90 100 110 120 DAALISYTAL LDIFFQMHDP STLNRQGEDL GSQYRSVIFY TTPSQKAQAE KTIKTLDENG 130 140 150 160 170 AFAKRIVTEV LPLTEFYPAE DYHHNYYAFN SSQPYCRFVI QPKLAKLKEH LPKL

References

[1]	"Genome sequence of the chlorinated compound-respiring bacterium Dehalococcoides species strain CBDB1." Kube M., Beck A., Zinder S.H., Kuhl H., Reinhardt R., Adrian L. Nat. Biotechnol. 23:1269-1273(2005) [PubMed: 16116419] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ965256 Genomic DNA. Translation: CAI83251.1.
RefSeq	YP_308167.1. NC_007356.1.
3D structure databases
ProteinModelPortal	Q3ZYC8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ZYC8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3623758.
GenomeReviews	Gene locus cbdbA1161 in contig AJ965256_GR.
KEGG	deh:cbdb_A1161.
NMPDR	fig|255470.3.peg.897.
PATRIC	21612327. VBIDehSp125902_0981.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HBG748152.
OMA	PYCRFVI.
PhylomeDB	Q3ZYC8.
ProtClustDB	CLSK837054.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q3ZYC8_DEHSC

Accession

Primary (citable) accession number: Q3ZYC8

Entry history

Integrated into UniProtKB/TrEMBL:	September 27, 2005
Last sequence update:	September 27, 2005
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)