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Q3ZE13

- RPP30_DICDI

UniProt

Q3ZE13 - RPP30_DICDI

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Protein
Ribonuclease P protein subunit drpp30
Gene
drpp30, rpp1, rpp30, DDB_G0269980
Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. RNA binding Source: dictyBase
  2. ribonuclease P activity Source: UniProtKB-EC
  3. tRNA binding Source: dictyBase

GO - Biological processi

  1. RNA phosphodiester bond hydrolysis Source: GOC
  2. RNA phosphodiester bond hydrolysis, endonucleolytic Source: GOC
  3. rRNA processing Source: dictyBase
  4. tRNA processing Source: dictyBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit drpp30 (EC:3.1.26.5)
Alternative name(s):
RNaseP protein 1
Gene namesi
Name:drpp30
Synonyms:rpp1, rpp30
ORF Names:DDB_G0269980
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
ProteomesiUP000002195: Chromosome 1, UP000002195: Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0269980. drpp30.

Subcellular locationi

Nucleus Reviewed prediction

GO - Cellular componenti

  1. nucleolar ribonuclease P complex Source: dictyBase
  2. ribonuclease MRP complex Source: dictyBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 366366Ribonuclease P protein subunit drpp30
PRO_0000240431Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB_0232069.

Structurei

3D structure databases

ProteinModelPortaliQ3ZE13.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi285 – 34763Thr-rich
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG273171.
KOiK03539.
OMAiVICKTMA.
PhylomeDBiQ3ZE13.

Family and domain databases

InterProiIPR016195. Pol/histidinol_Pase-like.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERiPTHR13031. PTHR13031. 1 hit.
PfamiPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMiSSF89550. SSF89550. 2 hits.

Sequencei

Sequence statusi: Complete.

Q3ZE13-1 [UniParc]FASTAAdd to Basket

« Hide

MVYYDLNIDS SLPEPKIKSM LSLHTKYGYD SVAITHTVEG KIGYKDVCKI    50
KKIQIEDDSE KSTSSGWMKM GDSNKTIKQY TRLQVICKTM AEFQMITANN 100
PVVQSYDIIS VVPYDVSVFN AACNSNEIDI ITIDTFSKFI IKPERVRQCI 150
AKGIFIEILY GNLFGIDADR IAFFQIASSL VRSSFGKNII LSSSGKSSTT 200
LRSPYDLSNL GHLFGLTFDQ AKAAVSKHPH TAVLHAITRR TKGIATVTDP 250
NLLKDLELWK LERKEDTQPT NNNIPHEKHI NKESTGKETI PKPTTTTTTT 300
TTTTTTAKTK TPTPTPTTEK TPSIPTQPPQ KPTAKSNKKT TTNTTSTAQK 350
QGKMDIDIDN NKRKRE 366
Length:366
Mass (Da):40,745
Last modified:May 2, 2006 - v1
Checksum:i7E9B6A63EF8FB09C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY940192 mRNA. Translation: AAY18218.1.
AAFI02000005 Genomic DNA. Translation: EAL72340.1.
RefSeqiXP_646444.1. XM_641352.1.

Genome annotation databases

EnsemblProtistsiDDB0232069; DDB0232069; DDB_G0269980.
GeneIDi8617403.
KEGGiddi:DDB_G0269980.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY940192 mRNA. Translation: AAY18218.1 .
AAFI02000005 Genomic DNA. Translation: EAL72340.1 .
RefSeqi XP_646444.1. XM_641352.1.

3D structure databases

ProteinModelPortali Q3ZE13.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 44689.DDB_0232069.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi DDB0232069 ; DDB0232069 ; DDB_G0269980 .
GeneIDi 8617403.
KEGGi ddi:DDB_G0269980.

Organism-specific databases

dictyBasei DDB_G0269980. drpp30.

Phylogenomic databases

eggNOGi NOG273171.
KOi K03539.
OMAi VICKTMA.
PhylomeDBi Q3ZE13.

Miscellaneous databases

PROi Q3ZE13.

Family and domain databases

InterProi IPR016195. Pol/histidinol_Pase-like.
IPR002738. RNase_P_p30.
[Graphical view ]
PANTHERi PTHR13031. PTHR13031. 1 hit.
Pfami PF01876. RNase_P_p30. 1 hit.
[Graphical view ]
SUPFAMi SSF89550. SSF89550. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of drpp1."
    Vourekas A., Kalavrizioti D., Zarkadis I.K., Stathopoulos C., Drainas D.
    Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: AX4.
  2. "The genome of the social amoeba Dictyostelium discoideum."
    Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N.
    , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
    Nature 435:43-57(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AX4.

Entry informationi

Entry nameiRPP30_DICDI
AccessioniPrimary (citable) accession number: Q3ZE13
Secondary accession number(s): Q55CN7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: May 2, 2006
Last modified: September 3, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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