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Protein
Submitted name:

DLG4 protein

Gene

DLG4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
DLG4 proteinImported
Gene namesi
Name:DLG4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ3ZCU5.
PeptideAtlasiQ3ZCU5.

Expressioni

Gene expression databases

BgeeiENSG00000132535.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000293813.

Structurei

3D structure databases

ProteinModelPortaliQ3ZCU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 72PDZ (DHR)InterPro annotationAdd BLAST72
Domaini138 – 219PDZ (DHR)InterPro annotationAdd BLAST82
Domaini253 – 323SH3InterPro annotationAdd BLAST71
Domaini359 – 534Guanylate kinase-likeInterPro annotationAdd BLAST176

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation
Contains 2 PDZ (DHR) domains.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0708. Eukaryota.
COG0194. LUCA.
HOVERGENiHBG107814.

Family and domain databases

Gene3Di2.30.42.10. 2 hits.
3.40.50.300. 2 hits.
InterProiIPR016313. DLG1.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR019583. PDZ_assoc.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR23119:SF33. PTHR23119:SF33. 1 hit.
PfamiPF00625. Guanylate_kin. 1 hit.
PF00595. PDZ. 2 hits.
PF10600. PDZ_assoc. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
SM00228. PDZ. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF50156. SSF50156. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q3ZCU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GGVGNQHIPG DNSIYVTKII EGGAAHKDGR LQIGDKILAV NSVGLEDVMH
60 70 80 90 100
EDAVAALKNT YDVVYLKVAK PSNAYLSDSY APPDITTSYS QHLDNEISHS
110 120 130 140 150
SYLGTDYPTA MTPTSPRRYS PVAKDLLGEE DIPREPRRIV IHRGSTGLGF
160 170 180 190 200
NIVGGEDGEG IFISFILAGG PADLSGELRK GDQILSVNGV DLRNASHEQA
210 220 230 240 250
AIALKNAGQT VTIIAQYKPE EYSRFEAKIH DLREQLMNSS LGSGTASLRS
260 270 280 290 300
NPKRGFYIRA LFDYDKTKDC GFLSQALSFR FGDVLHVIDA SDEEWWQARR
310 320 330 340 350
VHSDSETDDI GFIPSKRRVE RREWSRLKAK DWGSSSGSQG REDSVLSYET
360 370 380 390 400
VTQMEVHYAR PIIILGPTKD RANDDLLSEF PDKFGSCVPH TTRPKREYEI
410 420 430 440 450
DGRDYHFVSS REKMEKDIQA HKFIEAGQYN SHLYGTSVQS VREVAEQGKH
460 470 480 490 500
CILDVSANAV RRLQAAHLHP IAIFIRPRSL ENVLEINKRI TEEQARKAFD
510 520 530 540
RATKLEQEFT ECFSAIVEGD SFEEIYHKVK RVIEDLSGPY IWVPARERL
Length:549
Mass (Da):61,528
Last modified:September 27, 2005 - v1
Checksum:i6575914B0B0BF0BE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC040533 mRNA. Translation: AAH40533.1.
UniGeneiHs.463928.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC040533 mRNA. Translation: AAH40533.1.
UniGeneiHs.463928.

3D structure databases

ProteinModelPortaliQ3ZCU5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000293813.

Proteomic databases

PaxDbiQ3ZCU5.
PeptideAtlasiQ3ZCU5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0708. Eukaryota.
COG0194. LUCA.
HOVERGENiHBG107814.

Miscellaneous databases

ChiTaRSiDLG4. human.

Gene expression databases

BgeeiENSG00000132535.

Family and domain databases

Gene3Di2.30.42.10. 2 hits.
3.40.50.300. 2 hits.
InterProiIPR016313. DLG1.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR019583. PDZ_assoc.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR23119:SF33. PTHR23119:SF33. 1 hit.
PfamiPF00625. Guanylate_kin. 1 hit.
PF00595. PDZ. 2 hits.
PF10600. PDZ_assoc. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
SM00228. PDZ. 2 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF50156. SSF50156. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 2 hits.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ3ZCU5_HUMAN
AccessioniPrimary (citable) accession number: Q3ZCU5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 27, 2005
Last sequence update: September 27, 2005
Last modified: September 7, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.