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Q3ZCN5

- OTOGL_HUMAN

UniProt

Q3ZCN5 - OTOGL_HUMAN

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Protein

Otogelin-like protein

Gene

OTOGL

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. alpha-L-arabinofuranosidase activity Source: InterPro

GO - Biological processi

  1. L-arabinose metabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Otogelin-like protein
Gene namesi
Name:OTOGL
Synonyms:C12orf64
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 12

Organism-specific databases

HGNCiHGNC:26901. OTOGL.

Subcellular locationi

Secreted Curated

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Involvement in diseasei

Deafness, autosomal recessive, 84B (DFNB84B) [MIM:614944]: A form of non-syndromic deafness characterized by congenital, non-progressive, sensorineural, symmetric hearing loss. Vestibular hypofunction is rarely observed.1 Publication
Note: The disease is caused by mutations affecting the gene represented in this entry.

Keywords - Diseasei

Deafness, Non-syndromic deafness

Organism-specific databases

MIMi614944. phenotype.
Orphaneti90636. Autosomal recessive non-syndromic sensorineural deafness type DFNB.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 23322310Otogelin-like proteinPRO_0000316765Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi135 – 1351N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi136 ↔ 144By similarity
Glycosylationi425 – 4251N-linked (GlcNAc...)Sequence Analysis
Glycosylationi464 – 4641N-linked (GlcNAc...)Sequence Analysis
Glycosylationi817 – 8171N-linked (GlcNAc...)Sequence Analysis
Glycosylationi867 – 8671N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1280 – 12801N-linked (GlcNAc...)Sequence Analysis
Glycosylationi1583 – 15831N-linked (GlcNAc...)Sequence Analysis
Glycosylationi2177 – 21771N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi2240 ↔ 2296By similarity
Disulfide bondi2261 ↔ 2310By similarity
Disulfide bondi2272 ↔ 2327By similarity
Disulfide bondi2276 ↔ 2329By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ3ZCN5.
PRIDEiQ3ZCN5.

PTM databases

PhosphoSiteiQ3ZCN5.

Expressioni

Tissue specificityi

Expressed at high levels in fetal inner ear and heart. Low levels in fetal skeletal muscle, kidney, spleen and colon. Not detected in fetal liver, lung, brain, nor in fetal stomach. In adult tissues, highest levels in brain, kidney, heart and retina. Relatively low levels in lung, spleen and duodenum. Not detected in adult skeletal muscle, liver, nor testis.1 Publication

Gene expression databases

BgeeiQ3ZCN5.
CleanExiHS_C12orf64.
ExpressionAtlasiQ3ZCN5. baseline and differential.
GenevestigatoriQ3ZCN5.

Organism-specific databases

HPAiHPA040364.

Structurei

3D structure databases

ProteinModelPortaliQ3ZCN5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini113 – 326214VWFD 1PROSITE-ProRule annotationAdd
BLAST
Domaini381 – 43454TIL 1Add
BLAST
Domaini473 – 683211VWFD 2PROSITE-ProRule annotationAdd
BLAST
Domaini736 – 79156TIL 2Add
BLAST
Domaini938 – 1141204VWFD 3PROSITE-ProRule annotationAdd
BLAST
Domaini1514 – 1734221VWFD 4PROSITE-ProRule annotationAdd
BLAST
Domaini2240 – 233293CTCKPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1908 – 2095188Cys-richAdd
BLAST

Sequence similaritiesi

Belongs to the otogelin family.Curated
Contains 1 CTCK (C-terminal cystine knot-like) domain.PROSITE-ProRule annotation
Contains 4 VWFD domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiNOG325585.
GeneTreeiENSGT00760000118896.
HOGENOMiHOG000115301.
HOVERGENiHBG107710.
InParanoidiQ3ZCN5.
OrthoDBiEOG73V6J9.
TreeFamiTF330609.

Family and domain databases

InterProiIPR007934. AbfB.
IPR006207. Cys_knot_C.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001846. VWF_type-D.
[Graphical view]
PfamiPF05270. AbfB. 1 hit.
PF08742. C8. 4 hits.
PF01826. TIL. 2 hits.
PF00094. VWD. 4 hits.
[Graphical view]
SMARTiSM00832. C8. 4 hits.
SM00041. CT. 1 hit.
SM00216. VWD. 4 hits.
[Graphical view]
SUPFAMiSSF110221. SSF110221. 1 hit.
SSF57567. SSF57567. 4 hits.
PROSITEiPS01225. CTCK_2. 1 hit.
PS51233. VWFD. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3ZCN5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIPWSIFLLH VLLFSLQEYI CASSILMGTS KNGFNENRQK RALLAAQFEA
60 70 80 90 100
TSPRYFFHDA INWGESKIKG SCPYECLNGA FCSKTGTCDC QIFQALGTRC
110 120 130 140 150
QIIPNMGNGR DGICKTWGQY HFETFDGIYY YFPGNCSYIF AKDCGDLEPR
160 170 180 190 200
YTVWVHNSPK CLGSVYSCYR SISLFFSNQE EIRIYGHEIK KNGISLTLPQ
210 220 230 240 250
TIGQIFIEKL ADYILVKTTF GFSLAWDGIS GIYLKLSEDH KGKSCGLCGN
260 270 280 290 300
YNDIQSDDFI ILQEDYTEDI AMFANSWSVQ TPDDTKCVLT PSDFPNPCSS
310 320 330 340 350
GMPAFEAIFF KCQILLQFPF LSCHEYIDPY LYIASCVNDL CKTDDDETYC
360 370 380 390 400
RAATEYARAC SHAGYPIQDW RDDFPACTDK CDDSFVHRDC ISCCPPTCTF
410 420 430 440 450
EKQCLGSNLH CLDGCYCPDG LVMDNGTCIS LENCPCGFHG LAYSVGSKIE
460 470 480 490 500
QECTECVCVG GVWNCTEQDC PVQCSVVGDS HFTTFDGRHY SFIGMCQYIL
510 520 530 540 550
VKGTGKDKFT ITLQKAPCEQ NLGLVCLQSI TLILEDDFNK QVTLGRGGQI
560 570 580 590 600
LTSPNQGFNL NGIVEIQTLS SLFILLKTTF GLKILFAIDG ERIYIQLTSA
610 620 630 640 650
WKRRTLGLCG TFNGNIRDDF LSPSGMIEGT PQLHANAWRV SSTCFAPVHV
660 670 680 690 700
PVVDPCNINQ QNIGYAAHCD VIHQELFAPC HIYISPGLYY QLCRHDACKC
710 720 730 740 750
GSSCLCNALA HYAYLCGQHG VPIDFRTQIS FCAVVCQKGM LYHHCSSFCL
760 770 780 790 800
HSCISLSSPE QCSDDCAEGC NCPEGKFYED TLNFCVPIFH CRCHYRGSVY
810 820 830 840 850
QPGELIPTPS GLCQCSNGTV KCDELATPSA VHICPEGKEY FDCRFPDPEL
860 870 880 890 900
PAGGVNCETT CANLAMNFTC TPSSPCISGC VCAPGMAEHR GKCYVPESCP
910 920 930 940 950
CIWKDWEYLS GEVIATPCYT CVCRRGMFNC TYYPCPAVCT IYGDRHYYSF
960 970 980 990 1000
DGLEYDYISD CQVFLIKSAD DSDISVIAQN KKCFDNDIVC SKSVLISVGD
1010 1020 1030 1040 1050
TEIYLNDTPY KQKQSGFFLE NKSTYQLWKA GYYIVVYFPE KDITILWDRK
1060 1070 1080 1090 1100
TTIHIKVGPQ WKNKLSGLCG NFDKCTSNDM TTSNNLEVRN ARVFGDSWAL
1110 1120 1130 1140 1150
GQCESPDETI KPCEAHQNKF PYAKKECSIL YSDIFASCRN VIDVTSFAKN
1160 1170 1180 1190 1200
CHEDTCNCNL GGDCECLCTS IAAYAYKCCQ EGISIHWRSS TVCSLDCEYY
1210 1220 1230 1240 1250
NEGLGEGPYM LASYGQSGLV LGANMTSRSV FCLPRSSVHT SLFFYFMITP
1260 1270 1280 1290 1300
GLFKEKVSSL ALVSLESAER PNYFLYVHDN DTLSLELWEA NSAFHRRATF
1310 1320 1330 1340 1350
FHHQGLWIPG YSAFELYSKK GFFIIFTDSS VKASKYDDSE EFKHSSSFSI
1360 1370 1380 1390 1400
EEIQAAVPYR KMCEWRYEPC ATPCFKTCSD PEALACKFLP PVEGCLPYCP
1410 1420 1430 1440 1450
KNMILDEVTL KCVYPRDCIP VIPTEPTLMP PAKPTVPITV FDMLTPTTGL
1460 1470 1480 1490 1500
ECEPQKFDPV YDCSQYICLN MEWQLYNWSL NCPKDVEMPD CGFRGRPVQV
1510 1520 1530 1540 1550
NSDICCPEWE CPCRCSMLSE LSIITFDGNN AALYSMASYI LVRIPGEIIV
1560 1570 1580 1590 1600
AHIEKCSMNQ NGNSLKKLAP SGRISGLCFK KLNVTTPIHK IIVNRLARKV
1610 1620 1630 1640 1650
EVDSIVVPLP FSSQELSIED SGSMYVITTP AGLIIKWSHL TGIIDIHFGF
1660 1670 1680 1690 1700
RFNLSSYTEG LCGICNEDPD DDLRMQNGTI ITNMEDIGLF IESWEIEKSF
1710 1720 1730 1740 1750
EVTMRRPVRN CTEHDCSQCI DLLNRRIFIP CHDKVSPEDF CEKMWINYTY
1760 1770 1780 1790 1800
FWNYECDALS AYVALCNKFD ICIQWRTPDY CSLSCPEGKE YQPCVRPCEA
1810 1820 1830 1840 1850
RTCLNQWFYG HTSCLNLRED CVCKVGTILH RPHSAQCIPE KECACTDSED
1860 1870 1880 1890 1900
QPRTAGEIWN GGIDECTLYK CLENGSIIPI EPDCDEEPTP VCEREAEVVM
1910 1920 1930 1940 1950
GIIDKWTCCS KEVCGCDTTL CETSIPTCTN SQKLIVGHSP LSCCPQYKCE
1960 1970 1980 1990 2000
CDPLKCPSIS TPECREDQFM IQVRQEEPCC FSPFCVCESC TKPVPLCHDG
2010 2020 2030 2040 2050
EFLTVDLNST HFCCPQYYCV CEPNLCPMPL LNCAEDMNLV KENVSGQCCP
2060 2070 2080 2090 2100
TWHCECNCEN LIMPTCEVGE FTAIDHNFQS DCGCIQYLCE KDDVCVFQEV
2110 2120 2130 2140 2150
SVLNPGQSMI KYLEEDFCYA IECLEEKDNH TGFHTLNFTL VNCSKKCDVH
2160 2170 2180 2190 2200
QVYTPSPSDY GCCGTCKNVS CKFHMENGTS VVYAVGSTWH YNCTTYECVK
2210 2220 2230 2240 2250
TDEGAIILNY TMVCPPFNET ECKMNEGIVK LYNEGCCKIC KREERICQKV
2260 2270 2280 2290 2300
IIKSVIRKQD CMSQSPINVA SCDGKCPSAT IYNINIESHL RFCKCCRENG
2310 2320 2330
VRNLSVPLYC SGNGTEIMYT LQEPIDCTCQ WN
Length:2,332
Mass (Da):262,091
Last modified:February 6, 2013 - v5
Checksum:iD43BCCDB7727CB80
GO

Sequence cautioni

The sequence BAC04877.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
The sequence BAC11376.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti2062 – 20621I → V in BAC04877. (PubMed:14702039)Curated
Sequence conflicti2062 – 20621I → V in AAI01018. (PubMed:15489334)Curated
Sequence conflicti2062 – 20621I → V in AAI01019. (PubMed:15489334)Curated
Sequence conflicti2120 – 21201A → T in BAC04877. (PubMed:14702039)Curated
Sequence conflicti2120 – 21201A → T in BAC11376. (PubMed:14702039)Curated
Sequence conflicti2120 – 21201A → T in AAI01018. (PubMed:15489334)Curated
Sequence conflicti2120 – 21201A → T in AAI01019. (PubMed:15489334)Curated
Sequence conflicti2225 – 22251N → S in BAC11376. (PubMed:14702039)Curated
Sequence conflicti2225 – 22251N → S in AAI01018. (PubMed:15489334)Curated
Sequence conflicti2225 – 22251N → S in AAI01019. (PubMed:15489334)Curated
Sequence conflicti2253 – 22531K → E in BAC04877. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti1378 – 13781C → R.1 Publication
VAR_069040
Natural varianti2276 – 22761C → F in a breast cancer sample; somatic mutation. 1 Publication
VAR_038388

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC078817 Genomic DNA. No translation available.
AC083812 Genomic DNA. No translation available.
AC092945 Genomic DNA. No translation available.
AK075060 mRNA. Translation: BAC11376.1. Different initiation.
AK096852 mRNA. Translation: BAC04877.1. Different initiation.
BC101017 mRNA. Translation: AAI01018.3.
BC101018 mRNA. Translation: AAI01019.2.
UniGeneiHs.723594.

Genome annotation databases

EnsembliENST00000547103; ENSP00000447211; ENSG00000165899.
UCSCiuc021rba.1. human.

Polymorphism databases

DMDMi449081296.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC078817 Genomic DNA. No translation available.
AC083812 Genomic DNA. No translation available.
AC092945 Genomic DNA. No translation available.
AK075060 mRNA. Translation: BAC11376.1 . Different initiation.
AK096852 mRNA. Translation: BAC04877.1 . Different initiation.
BC101017 mRNA. Translation: AAI01018.3 .
BC101018 mRNA. Translation: AAI01019.2 .
UniGenei Hs.723594.

3D structure databases

ProteinModelPortali Q3ZCN5.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q3ZCN5.

Polymorphism databases

DMDMi 449081296.

Proteomic databases

PaxDbi Q3ZCN5.
PRIDEi Q3ZCN5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000547103 ; ENSP00000447211 ; ENSG00000165899 .
UCSCi uc021rba.1. human.

Organism-specific databases

GeneCardsi GC12P080603.
H-InvDB HIX0018423.
HGNCi HGNC:26901. OTOGL.
HPAi HPA040364.
MIMi 614925. gene.
614944. phenotype.
neXtProti NX_Q3ZCN5.
Orphaneti 90636. Autosomal recessive non-syndromic sensorineural deafness type DFNB.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG325585.
GeneTreei ENSGT00760000118896.
HOGENOMi HOG000115301.
HOVERGENi HBG107710.
InParanoidi Q3ZCN5.
OrthoDBi EOG73V6J9.
TreeFami TF330609.

Miscellaneous databases

NextBioi 35512394.
PROi Q3ZCN5.
SOURCEi Search...

Gene expression databases

Bgeei Q3ZCN5.
CleanExi HS_C12orf64.
ExpressionAtlasi Q3ZCN5. baseline and differential.
Genevestigatori Q3ZCN5.

Family and domain databases

InterProi IPR007934. AbfB.
IPR006207. Cys_knot_C.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR001846. VWF_type-D.
[Graphical view ]
Pfami PF05270. AbfB. 1 hit.
PF08742. C8. 4 hits.
PF01826. TIL. 2 hits.
PF00094. VWD. 4 hits.
[Graphical view ]
SMARTi SM00832. C8. 4 hits.
SM00041. CT. 1 hit.
SM00216. VWD. 4 hits.
[Graphical view ]
SUPFAMi SSF110221. SSF110221. 1 hit.
SSF57567. SSF57567. 4 hits.
PROSITEi PS01225. CTCK_2. 1 hit.
PS51233. VWFD. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1915-2332.
    Tissue: Placenta and Vascular endothelial cell.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1938-2332.
  4. Cited for: INVOLVEMENT IN DFNB84B, VARIANT ARG-1378, TISSUE SPECIFICITY.
  5. Cited for: VARIANT [LARGE SCALE ANALYSIS] PHE-2276.

Entry informationi

Entry nameiOTOGL_HUMAN
AccessioniPrimary (citable) accession number: Q3ZCN5
Secondary accession number(s): F8W0C3
, Q495U8, Q8N8G5, Q8NC28
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2013
Last modified: October 29, 2014
This is version 73 of the entry and version 5 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3