Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q3ZCN5

- OTOGL_HUMAN

UniProt

Q3ZCN5 - OTOGL_HUMAN

Protein

Otogelin-like protein

Gene

OTOGL

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 5 (06 Feb 2013)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. alpha-L-arabinofuranosidase activity Source: InterPro

    GO - Biological processi

    1. L-arabinose metabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Otogelin-like protein
    Gene namesi
    Name:OTOGL
    Synonyms:C12orf64
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:26901. OTOGL.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Involvement in diseasei

    Deafness, autosomal recessive, 84B (DFNB84B) [MIM:614944]: A form of non-syndromic deafness characterized by congenital, non-progressive, sensorineural, symmetric hearing loss. Vestibular hypofunction is rarely observed.1 Publication
    Note: The disease is caused by mutations affecting the gene represented in this entry.

    Keywords - Diseasei

    Deafness, Non-syndromic deafness

    Organism-specific databases

    MIMi614944. phenotype.
    Orphaneti90636. Autosomal recessive nonsyndromic sensorineural deafness type DFNB.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 23322310Otogelin-like proteinPRO_0000316765Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi135 – 1351N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi136 ↔ 144By similarity
    Glycosylationi425 – 4251N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi464 – 4641N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi817 – 8171N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi867 – 8671N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1280 – 12801N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1583 – 15831N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi2177 – 21771N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi2240 ↔ 2296By similarity
    Disulfide bondi2261 ↔ 2310By similarity
    Disulfide bondi2272 ↔ 2327By similarity
    Disulfide bondi2276 ↔ 2329By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PaxDbiQ3ZCN5.
    PRIDEiQ3ZCN5.

    PTM databases

    PhosphoSiteiQ3ZCN5.

    Expressioni

    Tissue specificityi

    Expressed at high levels in fetal inner ear and heart. Low levels in fetal skeletal muscle, kidney, spleen and colon. Not detected in fetal liver, lung, brain, nor in fetal stomach. In adult tissues, highest levels in brain, kidney, heart and retina. Relatively low levels in lung, spleen and duodenum. Not detected in adult skeletal muscle, liver, nor testis.1 Publication

    Gene expression databases

    ArrayExpressiQ3ZCN5.
    BgeeiQ3ZCN5.
    CleanExiHS_C12orf64.
    GenevestigatoriQ3ZCN5.

    Organism-specific databases

    HPAiHPA040364.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3ZCN5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini113 – 326214VWFD 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini381 – 43454TIL 1Add
    BLAST
    Domaini473 – 683211VWFD 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini736 – 79156TIL 2Add
    BLAST
    Domaini938 – 1141204VWFD 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini1514 – 1734221VWFD 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini2240 – 233293CTCKPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi1908 – 2095188Cys-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the otogelin family.Curated
    Contains 1 CTCK (C-terminal cystine knot-like) domain.PROSITE-ProRule annotation
    Contains 4 VWFD domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    eggNOGiNOG325585.
    HOGENOMiHOG000115301.
    HOVERGENiHBG107710.
    InParanoidiQ3ZCN5.
    OrthoDBiEOG73V6J9.
    TreeFamiTF330609.

    Family and domain databases

    InterProiIPR007934. AbfB.
    IPR006207. Cys_knot_C.
    IPR002919. TIL_dom.
    IPR014853. Unchr_dom_Cys-rich.
    IPR001846. VWF_type-D.
    [Graphical view]
    PfamiPF05270. AbfB. 1 hit.
    PF08742. C8. 4 hits.
    PF01826. TIL. 2 hits.
    PF00094. VWD. 4 hits.
    [Graphical view]
    SMARTiSM00832. C8. 4 hits.
    SM00041. CT. 1 hit.
    SM00216. VWD. 4 hits.
    [Graphical view]
    SUPFAMiSSF110221. SSF110221. 1 hit.
    SSF57567. SSF57567. 4 hits.
    PROSITEiPS01225. CTCK_2. 1 hit.
    PS51233. VWFD. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q3ZCN5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIPWSIFLLH VLLFSLQEYI CASSILMGTS KNGFNENRQK RALLAAQFEA     50
    TSPRYFFHDA INWGESKIKG SCPYECLNGA FCSKTGTCDC QIFQALGTRC 100
    QIIPNMGNGR DGICKTWGQY HFETFDGIYY YFPGNCSYIF AKDCGDLEPR 150
    YTVWVHNSPK CLGSVYSCYR SISLFFSNQE EIRIYGHEIK KNGISLTLPQ 200
    TIGQIFIEKL ADYILVKTTF GFSLAWDGIS GIYLKLSEDH KGKSCGLCGN 250
    YNDIQSDDFI ILQEDYTEDI AMFANSWSVQ TPDDTKCVLT PSDFPNPCSS 300
    GMPAFEAIFF KCQILLQFPF LSCHEYIDPY LYIASCVNDL CKTDDDETYC 350
    RAATEYARAC SHAGYPIQDW RDDFPACTDK CDDSFVHRDC ISCCPPTCTF 400
    EKQCLGSNLH CLDGCYCPDG LVMDNGTCIS LENCPCGFHG LAYSVGSKIE 450
    QECTECVCVG GVWNCTEQDC PVQCSVVGDS HFTTFDGRHY SFIGMCQYIL 500
    VKGTGKDKFT ITLQKAPCEQ NLGLVCLQSI TLILEDDFNK QVTLGRGGQI 550
    LTSPNQGFNL NGIVEIQTLS SLFILLKTTF GLKILFAIDG ERIYIQLTSA 600
    WKRRTLGLCG TFNGNIRDDF LSPSGMIEGT PQLHANAWRV SSTCFAPVHV 650
    PVVDPCNINQ QNIGYAAHCD VIHQELFAPC HIYISPGLYY QLCRHDACKC 700
    GSSCLCNALA HYAYLCGQHG VPIDFRTQIS FCAVVCQKGM LYHHCSSFCL 750
    HSCISLSSPE QCSDDCAEGC NCPEGKFYED TLNFCVPIFH CRCHYRGSVY 800
    QPGELIPTPS GLCQCSNGTV KCDELATPSA VHICPEGKEY FDCRFPDPEL 850
    PAGGVNCETT CANLAMNFTC TPSSPCISGC VCAPGMAEHR GKCYVPESCP 900
    CIWKDWEYLS GEVIATPCYT CVCRRGMFNC TYYPCPAVCT IYGDRHYYSF 950
    DGLEYDYISD CQVFLIKSAD DSDISVIAQN KKCFDNDIVC SKSVLISVGD 1000
    TEIYLNDTPY KQKQSGFFLE NKSTYQLWKA GYYIVVYFPE KDITILWDRK 1050
    TTIHIKVGPQ WKNKLSGLCG NFDKCTSNDM TTSNNLEVRN ARVFGDSWAL 1100
    GQCESPDETI KPCEAHQNKF PYAKKECSIL YSDIFASCRN VIDVTSFAKN 1150
    CHEDTCNCNL GGDCECLCTS IAAYAYKCCQ EGISIHWRSS TVCSLDCEYY 1200
    NEGLGEGPYM LASYGQSGLV LGANMTSRSV FCLPRSSVHT SLFFYFMITP 1250
    GLFKEKVSSL ALVSLESAER PNYFLYVHDN DTLSLELWEA NSAFHRRATF 1300
    FHHQGLWIPG YSAFELYSKK GFFIIFTDSS VKASKYDDSE EFKHSSSFSI 1350
    EEIQAAVPYR KMCEWRYEPC ATPCFKTCSD PEALACKFLP PVEGCLPYCP 1400
    KNMILDEVTL KCVYPRDCIP VIPTEPTLMP PAKPTVPITV FDMLTPTTGL 1450
    ECEPQKFDPV YDCSQYICLN MEWQLYNWSL NCPKDVEMPD CGFRGRPVQV 1500
    NSDICCPEWE CPCRCSMLSE LSIITFDGNN AALYSMASYI LVRIPGEIIV 1550
    AHIEKCSMNQ NGNSLKKLAP SGRISGLCFK KLNVTTPIHK IIVNRLARKV 1600
    EVDSIVVPLP FSSQELSIED SGSMYVITTP AGLIIKWSHL TGIIDIHFGF 1650
    RFNLSSYTEG LCGICNEDPD DDLRMQNGTI ITNMEDIGLF IESWEIEKSF 1700
    EVTMRRPVRN CTEHDCSQCI DLLNRRIFIP CHDKVSPEDF CEKMWINYTY 1750
    FWNYECDALS AYVALCNKFD ICIQWRTPDY CSLSCPEGKE YQPCVRPCEA 1800
    RTCLNQWFYG HTSCLNLRED CVCKVGTILH RPHSAQCIPE KECACTDSED 1850
    QPRTAGEIWN GGIDECTLYK CLENGSIIPI EPDCDEEPTP VCEREAEVVM 1900
    GIIDKWTCCS KEVCGCDTTL CETSIPTCTN SQKLIVGHSP LSCCPQYKCE 1950
    CDPLKCPSIS TPECREDQFM IQVRQEEPCC FSPFCVCESC TKPVPLCHDG 2000
    EFLTVDLNST HFCCPQYYCV CEPNLCPMPL LNCAEDMNLV KENVSGQCCP 2050
    TWHCECNCEN LIMPTCEVGE FTAIDHNFQS DCGCIQYLCE KDDVCVFQEV 2100
    SVLNPGQSMI KYLEEDFCYA IECLEEKDNH TGFHTLNFTL VNCSKKCDVH 2150
    QVYTPSPSDY GCCGTCKNVS CKFHMENGTS VVYAVGSTWH YNCTTYECVK 2200
    TDEGAIILNY TMVCPPFNET ECKMNEGIVK LYNEGCCKIC KREERICQKV 2250
    IIKSVIRKQD CMSQSPINVA SCDGKCPSAT IYNINIESHL RFCKCCRENG 2300
    VRNLSVPLYC SGNGTEIMYT LQEPIDCTCQ WN 2332
    Length:2,332
    Mass (Da):262,091
    Last modified:February 6, 2013 - v5
    Checksum:iD43BCCDB7727CB80
    GO

    Sequence cautioni

    The sequence BAC04877.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence BAC11376.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti2062 – 20621I → V in BAC04877. (PubMed:14702039)Curated
    Sequence conflicti2062 – 20621I → V in AAI01018. (PubMed:15489334)Curated
    Sequence conflicti2062 – 20621I → V in AAI01019. (PubMed:15489334)Curated
    Sequence conflicti2120 – 21201A → T in BAC04877. (PubMed:14702039)Curated
    Sequence conflicti2120 – 21201A → T in BAC11376. (PubMed:14702039)Curated
    Sequence conflicti2120 – 21201A → T in AAI01018. (PubMed:15489334)Curated
    Sequence conflicti2120 – 21201A → T in AAI01019. (PubMed:15489334)Curated
    Sequence conflicti2225 – 22251N → S in BAC11376. (PubMed:14702039)Curated
    Sequence conflicti2225 – 22251N → S in AAI01018. (PubMed:15489334)Curated
    Sequence conflicti2225 – 22251N → S in AAI01019. (PubMed:15489334)Curated
    Sequence conflicti2253 – 22531K → E in BAC04877. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti1378 – 13781C → R.1 Publication
    VAR_069040
    Natural varianti2276 – 22761C → F in a breast cancer sample; somatic mutation. 1 Publication
    VAR_038388

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC078817 Genomic DNA. No translation available.
    AC083812 Genomic DNA. No translation available.
    AC092945 Genomic DNA. No translation available.
    AK075060 mRNA. Translation: BAC11376.1. Different initiation.
    AK096852 mRNA. Translation: BAC04877.1. Different initiation.
    BC101017 mRNA. Translation: AAI01018.3.
    BC101018 mRNA. Translation: AAI01019.2.
    UniGeneiHs.723594.

    Genome annotation databases

    EnsembliENST00000547103; ENSP00000447211; ENSG00000165899.
    UCSCiuc021rba.1. human.

    Polymorphism databases

    DMDMi449081296.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC078817 Genomic DNA. No translation available.
    AC083812 Genomic DNA. No translation available.
    AC092945 Genomic DNA. No translation available.
    AK075060 mRNA. Translation: BAC11376.1 . Different initiation.
    AK096852 mRNA. Translation: BAC04877.1 . Different initiation.
    BC101017 mRNA. Translation: AAI01018.3 .
    BC101018 mRNA. Translation: AAI01019.2 .
    UniGenei Hs.723594.

    3D structure databases

    ProteinModelPortali Q3ZCN5.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q3ZCN5.

    Polymorphism databases

    DMDMi 449081296.

    Proteomic databases

    PaxDbi Q3ZCN5.
    PRIDEi Q3ZCN5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000547103 ; ENSP00000447211 ; ENSG00000165899 .
    UCSCi uc021rba.1. human.

    Organism-specific databases

    GeneCardsi GC12P080603.
    H-InvDB HIX0018423.
    HGNCi HGNC:26901. OTOGL.
    HPAi HPA040364.
    MIMi 614925. gene.
    614944. phenotype.
    neXtProti NX_Q3ZCN5.
    Orphaneti 90636. Autosomal recessive nonsyndromic sensorineural deafness type DFNB.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG325585.
    HOGENOMi HOG000115301.
    HOVERGENi HBG107710.
    InParanoidi Q3ZCN5.
    OrthoDBi EOG73V6J9.
    TreeFami TF330609.

    Miscellaneous databases

    NextBioi 35512394.
    PROi Q3ZCN5.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q3ZCN5.
    Bgeei Q3ZCN5.
    CleanExi HS_C12orf64.
    Genevestigatori Q3ZCN5.

    Family and domain databases

    InterProi IPR007934. AbfB.
    IPR006207. Cys_knot_C.
    IPR002919. TIL_dom.
    IPR014853. Unchr_dom_Cys-rich.
    IPR001846. VWF_type-D.
    [Graphical view ]
    Pfami PF05270. AbfB. 1 hit.
    PF08742. C8. 4 hits.
    PF01826. TIL. 2 hits.
    PF00094. VWD. 4 hits.
    [Graphical view ]
    SMARTi SM00832. C8. 4 hits.
    SM00041. CT. 1 hit.
    SM00216. VWD. 4 hits.
    [Graphical view ]
    SUPFAMi SSF110221. SSF110221. 1 hit.
    SSF57567. SSF57567. 4 hits.
    PROSITEi PS01225. CTCK_2. 1 hit.
    PS51233. VWFD. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The finished DNA sequence of human chromosome 12."
      Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
      , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
      Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1915-2332.
      Tissue: Placenta and Vascular endothelial cell.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1938-2332.
    4. Cited for: INVOLVEMENT IN DFNB84B, VARIANT ARG-1378, TISSUE SPECIFICITY.
    5. Cited for: VARIANT [LARGE SCALE ANALYSIS] PHE-2276.

    Entry informationi

    Entry nameiOTOGL_HUMAN
    AccessioniPrimary (citable) accession number: Q3ZCN5
    Secondary accession number(s): F8W0C3
    , Q495U8, Q8N8G5, Q8NC28
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: February 6, 2013
    Last modified: October 1, 2014
    This is version 72 of the entry and version 5 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3