Q3ZCN2 (Q3ZCN2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
RGL4 protein EMBL AAI01111.2

Gene names

Name:

RGL4 EMBL AAI01111.2

Organism

Homo sapiens (Human) EMBL AAI01111.2

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	536 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 Ras-GEF domain. SAAS SAAS001895

Ontologies

Keywords
Molecular function	Guanine-nucleotide releasing factor SAAS SAAS001895
Gene Ontology (GO)
Biological process	small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	536	1	EMBL AAI01111.2

Sequences

	Sequence		Length	Mass (Da)
	Q3ZCN2 [UniParc]. Last modified April 17, 2007. Version 2. Checksum: 4EE40E607C23FBAB	FASTA	536	59,361
	10 20 30 40 50 60 MRKLLTNLPA AAVLSAQVYS AVLRGLWEEN VCGTPGRTRV CTALLYGQVC PFQDSTDGLR 70 80 90 100 110 120 TITSILFNWP PENTSVYYQP PQRSSFRIKL AFRNLSWPGL GLEDHQEIVL GQLVLPEPNE 130 140 150 160 170 180 AKPDDPAPRP GQHALTMPAL EPAPPLLADL GPALEPESPA ALGPPGYLHS APGPAPAPGE 190 200 210 220 230 240 GPPPGTVLEP QSAPESSCPC RGSVKNQPSE ELPDMTTFPP RLLAEQLTLM DAELFKKVVL 250 260 270 280 290 300 YECLGCIWGQ GHLKGNEHMA PTVRATIAHF NRLTNCITTS CLGDHSMRAR DRARVVEHWI 310 320 330 340 350 360 KVARECLSLN NFSSVHVIVS ALCSNPIGQL HKTWAGVSSK SMKELKELCK KDTAVKRDLL 370 380 390 400 410 420 IKAGSFKVAT QERNPQRAQM RLRRQKKGVV PFLGDFLTEL QRLDSAIPDD LDGNTNKRSK 430 440 450 460 470 480 EVRVLQEMQL LQVAAMNYRL RPLEKFVTYF TRMEQLSDKE RWGFTMMSRI VSNSWPQAIH 490 500 510 520 530 PPQPPKVLTL QLQAVLPAGA RKPVGWQHPA VAGNPPGCWP EHRLCTIPHP DRRHQG

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: PCR rescued clones EMBL AAI01111.2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC101110 mRNA. Translation: AAI01111.2.
IPI	IPI00647817.
UniGene	Hs.658997.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3ZCN2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc002zxo.1. human.
Phylogenomic databases
eggNOG	prNOG14881.
HOVERGEN	HBG005864.
OrthoDB	EOG4DBTDN.
Gene expression databases
ArrayExpress	Q3ZCN2.
Family and domain databases
InterPro	IPR008937. Ras_GEF. IPR023578. Ras_GEF_dom. IPR001895. RasGRF_CDC25. [Graphical view]
Gene3D	G3DSA:1.10.840.10. RasGRF_CDC25. 1 hit.
PANTHER	PTHR23113. Ras_GEF. 1 hit.
Pfam	PF00617. RasGEF. 1 hit. [Graphical view]
SMART	SM00147. RasGEF. 1 hit. [Graphical view]
SUPFAM	SSF48366. Ras_GEF. 1 hit.
PROSITE	PS50009. RASGEF_CAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q3ZCN2_HUMAN

Accession

Primary (citable) accession number: Q3ZCN2

Entry history

Integrated into UniProtKB/TrEMBL:	September 27, 2005
Last sequence update:	April 17, 2007
Last modified:	November 16, 2011
This is version 42 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.